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Andreas F. Mavrogenis
Andreas F. Mavrogenis
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece
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Vasilios G. Igoumenou
Vasilios G. Igoumenou
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece
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Thekla Antoniadou
Thekla Antoniadou
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece
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Panayiotis D. Megaloikonomos
Panayiotis D. Megaloikonomos
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, Greece
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George Agrogiannis
George Agrogiannis
Second Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Greece
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Periklis Foukas
Periklis Foukas
Second Department of Pathology, National and Kapodistrian University of Athens, School of Medicine, Greece
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Sotirios G. Papageorgiou
Sotirios G. Papageorgiou
Second Department of Internal Medicine, Hematology Unit, National and Kapodistrian University of Athens, School of Medicine, Greece
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including polymorphic granulomae, fibrosis, xanthogranulomatosis, proliferating fibroblasts, lymphocytic aggregates and Touton giant cells. 12 Fig. 1 Histopathological findings of ECD. Bone tissue sections show intense fibrohistiocytic infiltrate
Xinhui Wu
Xinhui Wu
Department of Orthopedics, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
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Xiaoxin Fang
Xiaoxin Fang
Department of Endocrinology and Metabolism, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China
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Feng Lu
Feng Lu
Nanjing Medical University, Jiangning, Nanjing, China
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Qiong Chen
Qiong Chen
Jinhua TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
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Junjian Liu
Junjian Liu
Department of Orthopedics, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
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Longpo Zheng
Longpo Zheng
Department of Orthopedics, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
Orthopedic Intelligent Minimally Invasive Diagnosis and Treatment Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
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Orthopedic Intelligent Minimally Invasive Diagnosis and Treatment Center, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, China
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). Osteoclast in the setting of ferroptosis Mature osteoclasts are multinucleated giant cells originating from the monocyte/macrophage lineage. Osteoclasts break down and absorb bone matrix by secreting H + and proteolytic enzymes like cathepsin K ( 69
