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oestrogen in maintaining skeletal integrity is evidenced by the fact that osteoporosis is more common in women than in men and that fragility fractures markedly increase after menopause. Albright et al reported in the 1940s that oestrogen administration
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-demand prophylaxis). Since hypervascularity and a fragile state of the synovium last about six weeks after a bleed, a similar duration of secondary prophylaxis is recommended after each episode of haemarthrosis. About 15% to 20% of patients with haemophilia develop
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periprosthetic fractures that can occur either side of all TJAs and dislocation in THA. In this context it is desirable that the revision could be as uninvasive as possible, as well as tissue/implant sparing, especially in the older and more fragile patients