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’ condition TXA administration Outcomes He et al. ( 11 ) Low Degenerative conditions 10 mg/kg i.v. before skin incision + 6–8 mg/kg/h i.v. during the surgery IBL, total postoperative drainage, time for drainage removal, hospital stay
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Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China
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ultimately achieves the purpose of reducing the TBL. The study by Arun-Kumar et al. ( 27 ) included four groups: preoperative intravenous TXA, preoperative local infiltration of TXA in the paravertebral muscles at the incision, tTXA before closing the
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only be used in the subcutaneous and muscle around the incision. What happens if TXA enters the spinal canal or the cerebrospinal fluid? Recently, we used TXA local combined with intravenous administration in a patient with lumbar spine surgery for
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curve of Cobb > 25 degrees and progressive Cobb angle, or an RVAD (rib-vertebral angle difference) of more than 20 degrees 8 rib phase 2, or a double curve, cast correction is recommended. With curves less than 60 degrees a full recovery of the
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compression can be aggravated by neurological deficits caused by coexisting lesions, and the neurological response to single regional decompression is also lower in patients with TSS ( 57 ). Some studies used ‘double crush syndrome’ to explain the severity of
NeuroGen Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, Porto, Portugal
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Hospital das Forças Armadas, Porto, Portugal
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Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, Porto, Portugal
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Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, Porto, Portugal
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specified) and Kang, 2021 ( 25 ) (double-level surgery); *Values are mean ± s.d. ; † Some concerns. –, missing data; Bi, biportal; Endo, endoscopic; IL, interlaminar; LIF, lumbar interbody fusion; MIS, minimally invasive surgery; NOS, cohort study