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Shankar Aissvarya Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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King-Hwa Ling Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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Manohar Arumugam Department of Orthopaedics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
School of Medicine, Faculty of Medicine and Health Sciences, Taylor's University, Selangor, Malaysia

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Karuppiah Thilakavathy Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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this review, we addressed the genetic aspects and prior genetic investigations related to DC. Subsequently, we delve into a discussion of the molecular pathways that have been proposed to be associated with DC. Lastly, we provide a summary of the

Article Type:
Review Article
Category:
Hand & Wrist
DOI:
https://doi.org/10.1530/EOR-23-0056
Volume/Issue:
Volume 9: Issue 8
Open access
Elena Bravo Plastic Surgery Department, Hospital Universitario La Paz, Madrid, Spain

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Raul Barco Upper Limb Unit, Orthopedic Surgery Department, Hospital Universitario La Paz, Madrid, Spain

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E. Carlos Rodríguez-Merchán Haemophilia Orthopedic Unit, Orthopedic Surgery Department, Hospital Universitario La Paz, Madrid, Spain

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and molecular pathways, potential targets for arthropathy therapy are iron chelators, anti-inflammatory treatment, anti-fibrinolytic, and bone-remodelling agents. These options have demonstrated beneficial effects, predominantly in a preclinical

Article Type:
Review Article
Category:
Hand & Wrist
DOI:
https://doi.org/10.1302/2058-5241.5.190078
Volume/Issue:
Volume 5: Issue 6
Open access
Lars B. Dahlin Department of Translational Medicine - Hand Surgery, Lund University, and Skåne University Hospital, Malmö, Sweden

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Mikael Wiberg Department of Surgical and Perioperative Science, University Hospital, and Department of Integrative Medical Biology, Umeå University, Sweden

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purpose to create an optimal milieu for the axonal outgrowth after the injury. The proliferation of Schwann cells, forming an optimal pathway for the outgrowing axons, is accompanied by upregulation of a large number of different trophic factors in the

Article Type:
Research Article
Category:
Hand & Wrist
DOI:
https://doi.org/10.1302/2058-5241.2.160071
Volume/Issue:
Volume 2: Issue 5
Open access