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) In 2019, Aldemir and Duygun reviewed 28 aseptic tibial nonunions without bone defects (15 hypertrophic and 13 atrophic), with an average time from fracture to treatment of 1.6 years. 4 The previous treatments for these fractures had comprised
University of Lille, INSERM, CHU Lille, U1008 – Advanced Drug Delivery Systems and Biomaterials, Lille, France
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Introduction The management of critical bone loss in orthopedic and trauma surgery can be managed by the induced membrane technique (IMT), developed by A-C Masquelet ( 1 ). It consists of placing a PMMA spacer into the bone defect. A foreign
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relatively high mortality and comorbidity comparable to those of proximal femoral fractures ( 5 , 6 , 7 ). High-energy injuries frequently result in severe metaphyseal comminution, fractures extended into the articular surface, critical bone defects, or a
Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Justus Maximilian University Wuerzburg, König-Ludwig-Haus, Brettreichstraße, Würzburg, Germany
Paracelsus Medizinische Privatuniversität, Strubergasse, Salzburg, Austria
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany
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Ludwig Maximilian University Munich, Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Zentrum München (MUM), Marchionostraße, Munich, Germany
Working Group Clinical Tissue Regeneration of the German Society of Orthopaedics and Traumatology (DGOU), Berlin, Germany
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Martin-Luther-University Halle-Wittenberg, Universitätsklinikum Halle (Saale), DOUW - Abteilung für Unfall- und Wiederherstellungschirurgie, Ernst-Grube-Straße, Halle, Germany
BG-Klinikum Bergmannstrost Halle, Halle, Saale, Germany
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defect is perforated with a drill bit or a K-wire to stimulate bony healing. Additional bone grafting can be considered for bony defects and chronic lesions ( 19 ). Importantly, any sclerotic wall should be perforated several times. This treatment
Department of Orthopaedics and Traumatology, Freiburg University Hospital, Freiburg, Germany.
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shows poor callus formation on X-ray, has viable fracture fragments and a disturbed local biology or mechanics. An atrophic nonunion is mobile, has no callus, non-viable bone or a bone defect which is caused by impaired biology, often combined with
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subsequent failure. The aim of this manuscript is twofold: first, to describe the current techniques in reducing impacted osteochondral defects and the available bone filling materials; and second, to present our current understanding of impacted or
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. ( https://doi.org/10.1007/s00590-008-0343-4 ) 17. Streitbürger A Hardes J Nottrott M Guder WK . Reconstruction survival of segmental megaendoprostheses: a retrospective analysis of 28 patients treated for intercalary bone defects after
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Epidemiology Open fractures of the tibia are the most common open long bone fractures, with an annual incidence of 3.4 per 100 000. 1 , 2 The mean age of those who sustain open tibial fractures is 43.3 years, most frequently occurring in
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Department of Orthopaedic Surgery, University Hospital Antwerp, Antwerp, Belgium
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Department of Orthopaedic Surgery, University Hospital Antwerp, Antwerp, Belgium
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Department of Orthopaedic Surgery, University Hospital Antwerp, Antwerp, Belgium
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to the planned reduction. Autologous bone grafts are used to fill the defect at the osteotomy site. A patient-specific instrument can also be designed and printed to reproduce the pre-determined size of the graft accurately. Arthroscopy can be
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Department of Orthopaedic Surgery, International Knee and Joint Centre, Abu Dhabi, UAE
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. Arthroplasty for complex knee fractures requires thorough knowledge of the basic rules of revision surgery. Choice of constraint, joint-line restoration and component rotation, bone defect filling and implant fixation follow the same principles as in TKA