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been used. This review discusses current treatment options with a focus on chronic osteochondral defects of the knee. Bone marrow stimulation techniques Bone marrow stimulation procedures are commonly used to treat osteochondral lesions and are
Clínica Alemana-Universidad del Desarrollo, Santiago, Chile
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Hospital Padre Hurtado, Santiago, Chile
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3Bs Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Portugal; ICVS/3Bs–PT Government Associate Laboratory, Portugal
Orthopaedics Department of Minho University, Portugal
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defects, instability or malalignment should be amenable to surgical correction. On the other hand, classical contraindications are: advanced osteoarthritis, obesity, skeletal immaturity, inflammatory arthritis, previous septic arthritis, and synovial
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. 52 Ochi M , Uchio Y , Kawasaki K , Wakitani S , Iwasa J . Transplantation of cartilage-like tissue made by tissue engineering in the treatment of cartilage defects of the knee . J Bone Joint Surg [Br
Ripoll y De Prado Sports Clinic, Murcia-Madrid, FIFA Medical Centre of Excellence, Madrid, Spain
International Centre of Sports Traumatology of the Ave, Vila do Conde, Portugal
3Bs Research Group, I3Bs, Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Barco, Guimarães, Portugal
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ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal
Clínica do Dragão, Espregueira-Mendes Sports Centre, FIFA Medical Centre of Excellence, Porto, Portugal
Orthopedic Department, University of Minho, Braga, Portugal
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ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal
The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Avepark, Barco, Guimarães, Portugal
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ICVS/3Bs, PT Government Associate Laboratory, Braga/Guimarães, Portugal
Orthopaedic Department, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, Spain
The Discoveries Centre for Regenerative and Precision Medicine, Headquarters at University of Minho, Avepark, Barco, Guimarães, Portugal
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treated by an osteochondral allograft resurfacing procedure combining bone, cartilage, and meniscus in a single step. 46 , 47 The first free MAT was performed in 1984. 48 Since then the technique has been intensely developed and proposed for the
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weakness can also result from autograft harvesting for ACL reconstruction. A trend towards extensor and flexor muscle strength deficit was shown in ACL reconstructions when bone-patella-tendon-bone (BPTB) and hamstring (HST) autograft was used, respectively
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enhance healing after meniscal repair, a variety of augmentation techniques and biological products have been introduced: needling, trephination, platelet-rich plasma, bone marrow aspirate, hyaluronan-collagen scaffold, fibrin clot, fibrin glue
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potential of MSC while impeding their differentiation into adipocytes, thus contributing to the repair of cartilage matrix defects ( 76 ). In addition, experimental results have shown that long-term moderate-intensity exercise has favorable effects on bone
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain
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. Possible autografts to be used are the hamstring (gracilis and semitendinosus) tendon, bone-patella tendon-bone (BPTB), and quadriceps tendon (with or without a distal bone block). These grafts can be obtained from the injured knee or from the contralateral
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. The hallux sesamoid bones are paired ossicles of the foot. They function as a fulcrum to increase the leverage of both flexor hallucis brevis and longus. The medial sesamoid is typically larger than the lateral sesamoid and sits more distal. The medial
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degenerative joint changes that can result in a varus deformity and articular defects in the posteromedial tibial plateau due to abnormal kinematics and cartilage wear ( 26 , 27 ). These joint deformities represent a specific pattern that significantly differs