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Metagenomic next-generation sequencing in osteoarticular infections with a focus on pediatrics: current concepts and clinical applications

Marco Gupton

Marco Gupton MountainView Regional Medical Center, Orthopaedic Surgery Residency, Las Cruces, New Mexico, USA

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Jessica Burns

Jessica Burns Department of Orthopaedic Surgery, Phoenix Children’s Hospital, Phoenix, Arizona, USA

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). Due to the vast amount of data, some mNGS platforms have the disadvantage of barcode index switching, and this could lead to cross-contamination of samples and inaccurate results ( 32 , 93 ). Another difficulty is the storage and transfer of massive