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Juan Manuel Henríquez-Jurado Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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María Catalina Osuna-Pérez Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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Héctor García-López Department of Nursing, Physiotherapy and Medicine. University of Almería. Ctra Sacrament s/n, Almería, Spain

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Rafael Lomas-Vega Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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María del Carmen López-Ruiz Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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Esteban Obrero-Gaitán Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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Irene Cortés-Pérez Department of Health Sciences. University of Jaén. Campus Las Lagunillas s/n, Jaén, Spain

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therapeutic option to add to physiotherapy programs. There has been an increase in the creation and use of virtual reality hardware and software in physical rehabilitation, which has shown to be effective in pathologies such as total knee arthroplasty ( 25

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xuelei Zhang Department of Ultrasound, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Chengxin Xie Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Department of Endocrinology, Ministry of Education, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China
Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Luxia Wu Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Guoping Cai Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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thrombogenic biomarkers in total knee arthroplasty: study protocol . BMJ Open 2021 11 e038399 . ( https://doi.org/10.1136/bmjopen-2020-038399 ) 13 Emrah K Ali AH Utku O Murat K Kenan S & Deniz B . Efficacy of tranexamic acid on blood loss in

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