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, (3)aspirin prophylaxis was compared to other prophylactic agents, no prophylaxis or if different dosages of aspirin were compared. Both observational studies and randomized controlled trials (RCTs) were included. Only articles published in the last 30
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For this type of study, we included prospective and retrospective observational studies, randomized controlled trials, case-controlled studies and cohort studies. We excluded the following: review articles and case report studies; articles with only
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; functional status (using the Enneking/Musculo Skeletal Tumor Society (MSTS) score). We included all prospective and retrospective observational studies, randomized controlled trials, case-controlled studies, and cohort studies. We excluded review
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No randomized controlled trials were found, the seven articles that were included all were retrospective case-cohort studies, providing an OCEBM score of 3. The MINORS scores ranged from 7 to 13 ( Table 3 ). Primary outcome measures The
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controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma . Cancer 2008 ; 113 : 573 – 581 . 92. Demetri GD von Mehren M Jones RL et al. Efficacy and safety of trabectedin or dacarbazine
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osteosarcomas: results from the PEMBROSARC study . Eur J Cancer 2019 ; 119 : 151 – 157 . 50. Womer RB West DC Krailo MD et al. Randomized controlled trial of interval-compressed chemotherapy for the treatment of