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Olga D. Savvidou, Panagiotis Koutsouradis, George D. Chloros, Ioannis Papanastasiou, Thomas Sarlikiotis, Aggelos Kaspiris, and Panayiotis J. Papagelopoulos

respectively. 2 , 3 During recent decades advances in the diagnosis, management and prognosis of patients with bone tumours around the elbow have been made. Early diagnosis and preoperative planning is essential and can dramatically change the treatment

Olga Savvidou, Olympia Papakonstantinou, Eleftheria Lakiotaki, Ioannis Zafeiris, Dimitra Melissaridou, Pinelopi Korkolopoulou, and Panayiotis J. Papagelopoulos

features, the current treatment and the prognosis of juxtacortical bone tumours. Surface osteosarcomas Surface osteosarcomas are distinct clinicopathological entities of osteogenic tumours rather than a subtype of intramedullary conventional

Ajay Puri

) Classification of Tumors of Soft Tissue and Bone now separates chondrosarcoma into two International Classification of Diseases codes. This is reflective of the different prognosis of chondrosarcoma based on grade, with Grade I distinguished from Grade II and

Robert Grimer, Michael Parry, and Steven James

reported no difference in outcomes between patients undergoing early re-excision (before 32 days, the median in his series) and after 32 days. 17 Funovics et al found that undergoing re-excision within 12 weeks of initial IE led to a better prognosis

Olga Savvidou, Olympia Papakonstantinou, Eleftheria Lakiotaki, Dimitra Melissaridou, Pinelopi Korkolopoulou, and Panayiotis J. Papagelopoulos

resection or as a palliative treatment. 33 The prognosis of EO is poor, compared to conventional osteosarcoma, with a five-year survival rate of 28%. Tumour size is the best predictor of outcome. 35 More than 80–90% of patients develop local

Catalin Cirstoiu, Bogdan Cretu, Sergiu Iordache, Mihnea Popa, Bogdan Serban, and Adrian Cursaru

metastases is to restore an optimal functional status. Palliative treatment is appropriate when we have a generalized metastatic disease, surgically unapproachable metastases, metastases with extensive locoregional extension, or patients with a poor prognosis

Maria Anna Smolle, Dimosthenis Andreou, Per-Ulf Tunn, Joanna Szkandera, Bernadette Liegl-Atzwanger, and Andreas Leithner

prognosis. 56 Consequently, the most important step to take is urgent referral of these patients to a sarcoma centre, where further treatment will be planned and adequate re-resection or even amputation implemented. Treatment Treatment

Maria Anna Smolle, Joanna Szkandera, Dimosthenis Andreou, Emanuela Palmerini, Marko Bergovec, and Andreas Leithner

clinical phase. Bone sarcomas With five-year post-relapse survival rates of less than 30%, prognosis in advanced bone sarcomas is generally poor. 11 Yet, throughout the past years, several studies investigating novel treatment options have

Olga D. Savvidou, Panagiotis Koutsouradis, Ioanna K. Bolia, Angelos Kaspiris, George D. Chloros, and Panayiotis J. Papagelopoulos

, location, patient age, and presence of poorly differentiated areas determine the prognosis in patients with these lesions. Tumours located in the upper extremity have more favourable prognosis compared with those in the head and neck, axial or lower

Catalin Cirstoiu, Bogdan Cretu, Bogdan Serban, Zsombor Panti, and Mihai Nica

recurrence, associated with the worst prognosis, is mainly determined by tumour biology. This comes from the hypothesis that the patients with local recurrence are a subset of patients with extremely aggressive and chemoresistant tumours which would have a