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over the past decade has found that tissue concentrations for systemic antibiotic administration do not always meet the minimum inhibitory concentration (MIC) for effective prevention ( 1 ). Intraosseous (IO) techniques were originally used for fluid
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‘mesentery’ ( 2 ) and the early anatomists such as Cooper (1840) dissected out the osseous blood supply ( 3 ). Murray Brookes (1963) defined the intraosseous blood supply ( 4 ). Intraosseous pressure (IOP) has been investigated by several authors including
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intraosseous injection of methylprednisolone acetate into bone cysts and suggested repeating the treatment until the cyst healed. However, this treatment is nowadays reduced due to the morbidity associated with multiple injections and the risk of multiple
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incidence among these patients of 1.14%. 16 Pseudotumours may originate in soft tissues or subperiosteal or intraosseous areas caused by recurrent bleeding. They are classified into three types according to the anatomic sites where bleeding occurs. In
IRCCS Humanitas Research Hospital, Milan, Italy
These authors contributed equally to the article and should both be considered first authors
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IRCCS Humanitas Research Hospital, Milan, Italy
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First Moscow State Medical University – Sechenov University, Moscow, Russia
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IRCCS Humanitas Research Hospital, Milan, Italy
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therapy should be proposed with caution, especially when adopting biologic products, and further data should be collected before endorsing its routine application. Subchondral injections Subchondral injections refer to minimally invasive intra-osseous
Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland
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Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Bellinzona, Switzerland
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Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland
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Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland
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screw 2.7 mm 5-hole locking plate (Synthes) no compression screw Intraosseous fixation IO FIX® (Extr. Medical) + plantar dorsal Intraosseous fixation IO FIX® (Extr. Medical) + dorsal plantar
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that can compromise intra-osseous vascular flow. Many other aetiological factors can occur such as abnormal bone development in Kohler disease. Also, osteoarthritis, and systemic metabolic and autoimmune diseases that increase the risk of osteonecrosis
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bone growth and full return to physical activity (E, F). Intraosseous lipoma Cysts with a central calcification are likely to represent a less frequent intraosseous lipoma ( 43 , 44 ), but the distinction between SBC and lipoma can be
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construct failure of one of the devices. Other double fixation constructs Other variations of double fixation constructs have been used in a few case series. Bergin et al. ( 8 ) used an intraosseous plate in additional to a lateral extraosseous
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bone destruction is often more marked than the periosteal reaction, and can be appreciated on CT. MRI helps more than CT in biopsy to determine the intra-osseous and extra-osseous extent of the tumour. 15 Fig. 4 This ten-year-old female had a
