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histiocytoma (MFH) – average follow-up of 3.4 years, with no infection, dislocation, pressure ulcer, wound healing problems or mechanical failures – three deaths due to lung metastases, no local recurrence – average range of motion (ROM): shoulder abduction 45
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tibia”)) AND (“outcomes” OR “surgical revision” OR “pain” OR “range of motion” OR “recurrence” OR “metastases” OR “infection”))). Our initial search included GCT of bone from all the most affected locations in the appendicular skeleton, from which we
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: Recurrence of disease Osteoarthrosis The need for knee arthroplasty Secondary outcomes: Articular effusion Pain Limited range of motion Complications due to surgery: infection or wound dehiscence
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infection risk augmented by the immunosuppression (chemotherapy and/or radiation therapy); possible tumour cell activation; regenerate fracture; muscle contractures; nerve overstretching; implant failure; nonunion; delayed or premature union; axial or joint
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realized to favor strict adherence of vascularized soft tissues (p.e. muscles) obtaining stability, coverage of the implant, reduction of dead space, and the consequent risk of infection ( 20 , 24 , 25 , 30 ). Other relevant aspects are the need for a
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, and resection of the distal portion of the fibula due to tumor pathology. Exclusion criteria included studies not including resection of the distal portion of the fibula due to tumor pathology (i.e. resection after trauma or infection, cadaveric
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are common, and are far more likely to be the cause of a bone lesion seen in an elderly skeleton. Gout can mimic tumour, and this should be considered and queried in the adult history. Infection is also a great mimic. This should always be in the
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result in instability with high rates of complications such as implant loosening and failure and postoperative infection. Endoprosthetic replacement using a constrained hinged megaprosthesis ( Fig. 3a – h ) cannot allow good function compared to that
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. Infections and wound complications occur more frequently due to the immunocompromised status of patients. Treatment of complete and/or impending fractures and postoperative radiation A fracture that occurs in a modified bone is defined as a
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increased risk of developing postoperative infections. 10 Postoperative infection rates of 0–15% are reported for surgically treated femoral bone metastases, and are more frequently seen after placement of tumour prostheses. 11 Preoperative