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Marcel Niemann Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany

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Ellen Otto Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany

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Christian Eder Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Yasmin Youssef Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany

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Lutz Kaufner Charité – Universitätsmedizin Berlin, Department of Anesthesiology and Intensive Care Medicine, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Sven Märdian Charité – Universitätsmedizin Berlin, Center for Musculoskeletal Surgery, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany

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Introduction The European guideline on the management of major bleeding and coagulopathy following trauma is one of the most relevant sources for diagnostic and treatment algorithms in multiple injured patients ( 1 ). As trauma

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Julia Riemenschneider Department of Trauma-, Hand- and Reconstructive Surgery, Goethe University, Frankfurt, Germany

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Jan Tilmann Vollrath Department of Trauma-, Hand- and Reconstructive Surgery, Goethe University, Frankfurt, Germany

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Nils Mühlenfeld Department of Trauma-, Hand- and Reconstructive Surgery, Goethe University, Frankfurt, Germany

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Johannes Frank Department of Trauma-, Hand- and Reconstructive Surgery, Goethe University, Frankfurt, Germany

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Ingo Marzi Department of Trauma-, Hand- and Reconstructive Surgery, Goethe University, Frankfurt, Germany

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Maren Janko Department of Trauma-, Hand- and Reconstructive Surgery, Goethe University, Frankfurt, Germany

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non-operative treatment of acetabular fractures are not completely clear, since, to date, there is no evidence-based guideline for acetabular fractures and the surgical treatment in the literature. Based on retrospective and follow-up studies

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Ioannis V. Papachristos Academic Department of Trauma & Orthopaedics, School of Medicine, University of Leeds, UK

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Peter V. Giannoudis Academic Department of Trauma & Orthopaedics, School of Medicine, University of Leeds, UK
NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK

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advised that only 24 hrs delay should be adequate. 47 All these recommendations were established for elective planned surgery and not in an acute fractured hip setting where early surgery is one of the top priorities. In its general guideline for AF

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Duy Nguyen Anh Tran The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Bao Tu Thai Nguyen The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Tan Thanh Nguyen Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Yu-Pin Chen Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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Yi-Jie Kuo Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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TC Mulrow CD Shamseer L Tetzlaff JM Akl EA Brennan SE , et al . The PRISMA 2020 statement: an updated guideline for reporting systematic reviews . BMJ 2021 372 n71 . ( https://doi.org/10.1136/bmj.n71 ) 32 Wells GA Shea B O

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Cora Rebecca Schindler Department of Trauma-, Hand and Reconstructive Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany

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Ramona Sturm Department of Trauma-, Hand and Reconstructive Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany

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Jason Alexander Hörauf Department of Trauma-, Hand and Reconstructive Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany

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Ingo Marzi Department of Trauma-, Hand and Reconstructive Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany

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Philipp Störmann Department of Trauma-, Hand and Reconstructive Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany

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classification of fractures. To date, modern fracture treatment and guideline development are based, among other things, on the 2018 version of the AO Fracture and Dislocation Compendium. Imaging diagnostics are required for the classification. The bone involved

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Allan Roy Sekeitto Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Nkhodiseni Sikhauli Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Dick Ronald van der Jagt Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Lipalo Mokete Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Jurek R.T. Pietrzak Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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. National Institute for Health and Care Excellence . Osteoporosis . Clinical guideline QS149 . London : NICE , 2017 . http://www.nice.org.uk/guidance/qs149 ( 2017 , date last accessed 11 March 2020 ). 18. Pandey A Galvani AP

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Juan Ramón Cano Department of Orthopaedic Surgery and Traumatology, Hospital Universitario Costa del Sol, University of Málaga, Malaga, Spain

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José Manuel Bogallo Department of Orthopaedic Surgery and Traumatology, Hospital Universitario Costa del Sol, University of Málaga, Malaga, Spain

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Alicia Ramirez Department of Orthopaedic Surgery and Traumatology, Hospital Universitario Costa del Sol, University of Málaga, Malaga, Spain

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Enrique Guerado Department of Orthopaedic Surgery and Traumatology, Hospital Universitario Costa del Sol, University of Málaga, Malaga, Spain

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, is reinforced by the fact that the value of clinical assessment to identify major bleeding is very limited ( 13 ). The Société Française d’Anesthésie et de Réanimation (SFAR) Guideline panel provided 22 statements on pre-hospital and hospital

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Andreas Frodl Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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Benjamin Erdle Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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Hagen Schmal Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany
University Hospital Odense, Dep. Of Orthopedic Surgery, Sdr. Boulevard 29, 5000 Odense C, Denmark

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or evidence-based guideline to date concerning the treatment of distal lower-leg fractures. Summarizing the outcomes of this meta-analysis, our study’s key finding is that malunion, as manifested by a postoperative valgus/varus deviation, is

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Benedikt Johannes Braun Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Jörg Holstein Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Tobias Fritz Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Nils Thomas Veith Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Steven Herath Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Philipp Mörsdorf Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Tim Pohlemann Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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clopidogrel and aspirin on blood loss in hip fracture surgery . Injury 2011 ; 42 : 1277 - 82 . 20 Tazarourte K , Riou B , Tremey B , et al. ; EPAHK study group . Guideline-concordant administration of prothrombin complex

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Andreas Frodl Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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Johannes Hauss Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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Andreas Fuchs Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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Markus Siegel Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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Hagen Schmal Department of Orthopedic Surgery, University Hospital Odense, Odense, Denmark

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Jan Kühle Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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plot: time of surgery. Discussion There is no consensus or evidence-based guideline to date concerning the treatment of distal, extraarticular femur fractures. Summarizing the outcomes of this meta-analysis, our study’s key finding is

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