Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania
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fail due to advanced local destruction, resection and reconstruction may avoid subjecting the patient to secondary intervention. In the case of a bone metastasis associated with a pathological bone fracture, osteosynthesis or reconstruction should be
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revision surgery for failed distal femoral prosthesis using the Compress Compliant Pre-stress (CPS; Zimmer Biomet, Warsaw, IN, USA) implant – cumulative incidence for mechanical failure was 11%, occurring after a median of five months – incidence of
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reporting a range of 9% to 22% for the humerus 36 , 46 , 47 and 10% to 30% for the femur. 1 , 4 , 22 , 24 , 39 These are mostly related to the poor quality of bone, failed implant selection, progression of the disease, the condition of the patient
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. ( 17 ) reported 96% complete resolution of pain, 70% complete ossification, and 26% partial ossification without an increase in cyst size after polidocanol injection. They reported no recurrences, and only one case failed to heal and needed curettage
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resection and posterolateral fixation, local recurrence occurred; therefore, denosumab therapy was initiated. It failed, however, to stabilise the recurrent lesion and the formation of pulmonary metastases, and a rapid progression occurred. Reevaluation of
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meaningful tumour response after failed response to first-line anthracycline-based CTX, with a median PFS of 19 months (95% confidence interval (95% CI): 11 months to 27 months). 31 Pazopanib was also shown to be active in metastatic or unresectable
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following failed total elbow arthroplasty. 45 In light of current molecular biological understanding regarding the implication of the RANKL molecular pathway in the pathogenesis of GCT of bone, systemic targeted therapy has been advocated. In cases of
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. Curr Surg Rep 2014 ; 2 : 49 . 26 Miller BJ , Soni EE , Gibbs CP , Scarborough MT . Intramedullary nails for long bone metastases: why do they fail? Orthopedics 2011 ; 11 : 34 . 27 Harvey N
University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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University Emergency Hospital Bucharest, Romania
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surgical control or delayed (secondary) amputations after a failed limb-sparing procedure. Another instance when amputation can be performed is when it serves as a palliative measure for non-resectable tumours complicated with pathological fractures, soft
These authors contributed equally to this manuscript
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These authors contributed equally to this manuscript
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any spindle cell tumour invading muscle, such as myxoid liposarcoma or desmoid-type fibromatosis ( Fig. 7 ). 27 Moreover, fine needle biopsy samples often fail to depict the actual architecture of the lesion, as it is very difficult to identify