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Wen-xi Sun State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China

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Wei-qiang Huang State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China

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Hua-yang Li State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China

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Hong-shen Wang State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China

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Sheng-li Guo State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China

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Jie Dong Huizhou Hospital of Guangzhou University of Chinese Medicine, Huizhou, China

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Bo-lai Chen State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China

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Yong-peng Lin State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China

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.76%)  Cerebrospinal fluid leak 1 (0.13%) 3 (0.38%)  Decreased muscle strength 1 (0.13%) 1 (0.13%)  Dural injury 0 1 (0.13%) Total 38 (4.83%) 119 (14.97%) FH, freehand; RA, robot assisted. Clinical efficacy

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Guo-xu Zhang Guangzhou University of Chinese Medicine, Guangzhou, China

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Ji Li Guangzhou University of Chinese Medicine, Guangzhou, China

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Qi-jun Xie Guangzhou University of Chinese Medicine, Guangzhou, China

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Mei-ren Zhang Guangdong Hospital of Traditional Chinese Medicine, Guangzhou, China

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Kui Zhao Guangdong Hospital of Traditional Chinese Medicine, Guangzhou, China

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Hai-yun Chen Guangdong Hospital of Traditional Chinese Medicine, Guangzhou, China

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primarily employs meta-analysis to compare the clinical efficacy and postoperative complications of two surgical methods for treating comminuted fractures of the distal femur. Materials and methods This meta-analysis was performed according to the

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Wen-xi Sun Guangzhou University of Chinese Medicine, Guangzhou, China

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Hao-nan Liu Guangzhou University of Chinese Medicine, Guangzhou, China

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Meng-tong Chen Guangzhou University of Chinese Medicine, Guangzhou, China

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Yong-peng Lin Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China

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Hong-shen Wang Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China

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Bo-lai Chen Guangzhou University of Chinese Medicine, Guangzhou, China
Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China

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increasingly recognized by orthopaedic surgeons. They have gradually become widely used clinical procedures. However, there is still debate as to which of these two techniques is more advantageous ( 6 ). A meta-analysis of the clinical efficacy and safety of

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Önder İ. Kılıçoğlu Department of Orthopaedics and Traumatology, İstanbul University, Istanbul Faculty of Medicine, Turkey

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Mehmet Demirel Department of Orthopaedics and Traumatology, İstanbul University, Istanbul Faculty of Medicine, Turkey

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Şamil Aktaş Department of Underwater and Hyperbaric Medicine, İstanbul University, Istanbul Faculty of Medicine, Turkey

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that produces GFs and different extracellular matrix elements. 2 , 15 , 41 Although these products are the benchmarks of biological therapies, 41 further RCTs are needed to evaluate the clinical efficacy and safety of such therapies. 15

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Xun Wang Department of Orthopedics, Center for Plastic & Reconstructive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China
Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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Aiqi Zhang Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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Wenchao Yao Department of Orthopaedics, the First People's Hospital of Chun'an County, Hangzhou, Zhejiang, China

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Haiyan Qiu Department of Endocrinology, Afliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

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Fabo Feng Department of Orthopedics, Center for Plastic & Reconstructive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China

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fusion (MIS-TLIF), percutaneous endoscopic transforaminal lumbar interbody fusion (PETLIF), and robot-assisted minimally invasive TLIF have emerged. These techniques have achieved good clinical efficacy in reducing iatrogenic injury, shortening hospital

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Mustafa S. Rashid Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK

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Yves Tourné Institut Grenoblois de Chirurgie du Pied, Echirolles, France

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Kar H. Teoh Princess Alexandra Hospital, Harlow, UK

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clinical efficacy and clinical effectiveness of LIPUS therapy in the foot and ankle exist. A clinical efficacy study investigating the use of LIPUS therapy in a particular area, such as delayed unions in 5th metatarsal fractures, may utilize a double

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Miguel Relvas-Silva Department of Orthopaedics and Traumatology, São João Universitary Hospital Centre, Porto, Portugal
NeuroGen Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, Porto, Portugal

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Bernardo Sousa Pinto MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine, University of Porto, Porto, Portugal
CINTESIS@RISE - Health Research Network, MEDCIDS, Faculty of Medicine, University of Porto, Porto, Portugal

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António Sousa Department of Orthopaedics and Traumatology, São João Universitary Hospital Centre, Porto, Portugal

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Miguel Loureiro Department of Orthopaedics and Traumatology, São João Universitary Hospital Centre, Porto, Portugal
Hospital das Forças Armadas, Porto, Portugal

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André Rodrigues Pinho Department of Orthopaedics and Traumatology, São João Universitary Hospital Centre, Porto, Portugal
Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, Porto, Portugal

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Pedro Pereira NeuroGen Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, Porto, Portugal
CINTESIS@RISE - Health Research Network, MEDCIDS, Faculty of Medicine, University of Porto, Porto, Portugal
Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, Porto, Portugal

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. Research Square 2020 . ( https://doi.org/10.21203/rs.3.rs-89182/v1 ) 16 Ge M Zhang Y Ying H Feng C Li Y Tian J Zhao T Shao H & Huang Y . Comparison of hidden blood loss and clinical efficacy of percutaneous endoscopic transforaminal

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Mahmut Nedim Doral Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Department of Sports Medicine, Ankara, Turkey

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Onur Bilge Konya N.E. University, Meram Faculty of Medicine, Department of Orthopaedics and Traumatology, Department of Sports Medicine, Konya, Turkey

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Gazi Huri Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey

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Egemen Turhan Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey

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René Verdonk Ghent University, Faculty of Medicine, Department of Orthopaedics and Traumatology, De Pintelaan, Ghent, Belgium

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implants. These procedures can be performed arthroscopically, as described previously. 78 Regarding clinical efficacy, good mid-term and long-term clinical outcomes of polyurethane-based scaffolds and CMI were recently reported. 82 - 85 Currently

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Maria Anna Smolle Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Joanna Szkandera Division of Clinical Oncology, Internal Medicine, Medical University of Graz, Graz, Austria

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Dimosthenis Andreou Division of Orthopaedic Oncology and Sarcoma Surgery, Helios Klinikum Bad Saarow, Sarcoma Center Berlin-Brandenburg, Berlin, Germany

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Emanuela Palmerini Chemotherapy Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna University, Bologna, Italy

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Marko Bergovec Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Andreas Leithner Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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respective studies. Furthermore, study limitations, levels of evidence according to the Oxford Centre for Evidence Based Medicine Levels of Evidence Scale, 10 and clinical efficacy in distinct histological subtypes were documented. Fig. 1 PRISMA

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James Plant Royal National Orthopaedic Hospital, Stanmore, UK

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Stephen Cannon Royal National Orthopaedic Hospital, Stanmore, UK

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-S , et al. . The clinical efficacy of (18)F-FDG-PET/CT in benign and malignant musculoskeletal tumors . Ann Nucl Med 2008 ; 22 : 603 - 9 . 9 Dimitrakopoulou-Strauss A , Strauss LG , Heichel T , et al. . The role

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