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Vikki Wylde Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, UK.

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Andrew Beswick Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.

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Julie Bruce Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, UK.

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Ashley Blom Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, UK.
North Bristol NHS Trust, Southmead Hospital, Bristol, UK.

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Nicholas Howells North Bristol NHS Trust, Southmead Hospital, Bristol, UK.

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Rachael Gooberman-Hill Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, UK.
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, UK.

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Introduction The International Association for the Study of Pain (IASP) defines chronic pain as pain persisting for three months or longer. 1 Chronic post-surgical pain is widely accepted to be pain of at least three to six months

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Qiuyuan Wang Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China
Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Feng Li Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Yidan Yang Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Chen Yue Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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Jiayi Guo Department of Evidence-based Medicine, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China
Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China

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thrombosis, chronic pain, pruritus, and sedation). Data were independently extracted and inputted into an Excel spreadsheet, and the risk of bias for each eligible article was assessed by two authors. Disagreements were resolved during meetings with all

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Cheuk Yin Li School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Kenneth Jordan Ng Cheong Chung School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Omar M. E. Ali School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Nicholas D. H. Chung School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Cheuk Heng Li School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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contributes to chronic pain, which also highlights the importance of early diagnosis and appropriate management following TKR. 113 , 114 In addition, with reduced revision frequency, the risks patients are exposed to from invasive surgical procedures are

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Fabio A. Rodriguez-Patarroyo Outcomes Research Department, Anesthesiology Institute, Cleveland Clinic Ohio, USA

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Nadin Cuello Department of Orthopaedic and Trauma Surgery, Hospital Interzonal General de Agudos Eva Perón, San Martín, Buenos Aires, Argentina

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Robert Molloy Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio, USA

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Viktor Krebs Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio, USA

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Alparslan Turan Outcomes Research Department, Anesthesiology Institute, Cleveland Clinic Ohio, USA
Department of Anesthesiology, Cleveland Clinic, Cleveland, Ohio, USA

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Nicolas S. Piuzzi Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio, USA

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knee. 103 Most recent applications include postoperative chronic pain management after TKA. 104 With fluoroscopic guidance, pain physicians use needles to target the periosteal areas at the superior lateral, superior medial, inferior medial borders of

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Theofilos Karachalios School of Health Sciences, Faculty of Medicine, University of Thessalia, Greece
Orthopaedic Department, University General Hospital of Larissa, Greece

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George A. Komnos Orthopaedic Department, University General Hospital of Larissa, Greece

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Bruce J Blom A Howells N Gooberman-Hill R . Chronic pain after total knee arthroplasty . EFORT Open Rev 2018 ; 3 : 461 – 470 . 13. Walker LC Clement ND Ghosh KM Deehan DJ

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Vikki Wylde Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, UK
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, UK

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Neil Artz Department of Allied Health Professions, University of the West of England, Bristol, UK

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Nick Howells North Bristol NHS Trust, Southmead Hospital, Bristol, UK

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Ashley W. Blom Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, UK
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, UK
North Bristol NHS Trust, Southmead Hospital, Bristol, UK

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’s perceptions of remaining physically active and living with chronic pain . Qual Health Res 2014 ; 24 : 761 – 772 . 32. Davis AM Perruccio AV Ibrahim S et al. The trajectory of recovery and the inter-relationships of

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Joost van Tilburg Department of Orthopedics, Herlev Gentofte Hospital, Hellerup, Copenhagen, Denmark

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Mikkel Rathsach Andersen Department of Orthopedics, Herlev Gentofte Hospital, Hellerup, Copenhagen, Denmark

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.5% Thromboembolic events: 1.9% Superficial wound infection: 9.2% Superficial wound infection: 4.6% 90 days readmission: 8.7% 90 days readmission: 6.2% Spicer et al. (23) 2001 NR NR *4% had chronic pain prior to TKA

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Kara McConaghy Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

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Tabitha Derr Implant Research Core, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA

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Robert M. Molloy Cleveland Clinic, Department of Orthopedic Surgery, Cleveland, Ohio, USA

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Alison K. Klika Cleveland Clinic, Department of Orthopedic Surgery, Cleveland, Ohio, USA

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Steven Kurtz Implant Research Core, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA
Exponent, Philadelphia, Pennsylvania, USA

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Nicolas S. Piuzzi Cleveland Clinic, Department of Orthopedic Surgery, Cleveland, Ohio, USA

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patients are more likely to have complications such as subluxation, dislocation, and chronic pain. 55 Traditionally, medialization of the patellar prosthesis has been recommended. 56 , 57 Using this technique, the patellar component is placed medial to

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Alessandro Bensa Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Alessandro Sangiorgio Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Angelo Boffa Applied and Translational Research (ATR) Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Manuela Salerno Applied and Translational Research (ATR) Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Giacomo Moraca Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Giuseppe Filardo Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland
Applied and Translational Research (ATR) Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Università della Svizzera Italiana, Faculty of Biomedical Sciences, Lugano, Switzerland

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Rheumatology 2022 74 223 – 226 . ( https://doi.org/10.1002/art.42031 ) 53 Olsen MF Bjerre E Hansen MD Tendal B Hilden J & Hróbjartsson A . Minimum clinically important differences in chronic pain vary considerably by baseline pain and

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