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Olga D. Savvidou First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Panagiotis Koutsouradis Department of Orthopaedic Surgery, 417 Veterans Hospital (NIMTS), Athens, Greece

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George D. Chloros First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Ioannis Papanastasiou First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Thomas Sarlikiotis First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Aggelos Kaspiris Laboratory of Molecular Pharmacology/ Sector for Bone Research, School of Health Sciences, University of Patras, Patras, Greece

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Panayiotis J. Papagelopoulos First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Introduction Bone tumours around the elbow are rare and their incidence is approximately 1%. 1 The literature regarding primary bone tumours of the elbow is sparse, with only two case series consisting of 75 patients and 25 patients

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James Plant Royal National Orthopaedic Hospital, Stanmore, UK

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Stephen Cannon Royal National Orthopaedic Hospital, Stanmore, UK

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Introduction Primary bone tumours are rare, with an incidence in the United Kingdom of around six cases per million of the population. The general orthopaedic surgeon may only encounter one or two in their life’s practice. It is therefore

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Ajay Puri Department of Surgery, Tata Memorial Hospital, HBNI, Mumbai

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tumours can be quite challenging to diagnose, it is best for these lesions to be discussed in a multidisciplinary meeting which includes a radiologist and a pathologist specializing in bone tumours. Mesenchymal chondrosarcoma, an aggressive histological

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Antal Imre Department of Orthopaedics, Semmelweis University, Budapest, Hungary

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Sápi Zoltán Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest

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Szendrői Miklós Department of Orthopaedics, Semmelweis University, Budapest, Hungary

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European Medical Agency (EMA) for GCTB under certain indications (tumours requiring morbid surgery, unresectable or metastatic GCTB). GCTB is defined by the WHO as a locally aggressive, rarely metastasising bone tumour of intermediate dignity ( 4 ). GCTB

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Olga Savvidou First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece
These authors contributed equally to this manuscript

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Olympia Papakonstantinou Second Department of Radiology, National and Kapodistrian University of Athens, Medical School, Attikon University General Hospital, Athens, Greece
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Eleftheria Lakiotaki First Department of Pathology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece
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Ioannis Zafeiris First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece

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Dimitra Melissaridou First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece

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Pinelopi Korkolopoulou First Department of Pathology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece
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Panayiotis J. Papagelopoulos First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece
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Introduction Surface bone tumours are neoplasms situated near the bone cortex. They are classified into five different types: osseous, cartilaginous, fibrous, lipomatous and metastatic tumours. The most common types are those producing bone

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Olga Savvidou First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
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Olympia Papakonstantinou Second Department of Radiology, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Athens, Greece
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Eleftheria Lakiotaki First Department of Pathology, National and Kapodistrian University of Athens, LAIKON General Hospital, Athens, Greece
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Dimitra Melissaridou First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece

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Pinelopi Korkolopoulou First Department of Pathology, National and Kapodistrian University of Athens, LAIKON General Hospital, Athens, Greece
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Panayiotis J. Papagelopoulos First Department of Orthopedics, National and Kapodistrian University of Athens, Medical School, ATTIKON University General Hospital, Greece
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painless bone tumour Slowly growing bone tumour, occasionally painful Swelling and/or pain, bone tumour Slowly growing soft tissue tumour +/– painful, swelling, decreased ROM Painless, enlarging palpable soft tissue tumour, decreased ROM

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Maria A. Smolle Department of Orthopaedics and Trauma, Medical University of Graz, Austria

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Dimosthenis Andreou Department of General Orthopaedics and Tumour Orthopaedics, University Hospital Muenster, Germany

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Per-Ulf Tunn Tumour Orthopaedics, HELIOS Klinikum Berlin-Buch, Germany

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Andreas Leithner Department of Orthopaedics and Trauma, Medical University of Graz, Austria

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(LDK, Co., Ltd, Haidian, Beijing, China) polypropylene mesh composite (PROLENE® light mesh, Ethicon) after bone tumour resection of the proximal humerus. 5 In that study, a mean MSTS score of 66.7% at last follow-up was reported. 5 In a

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Stijn E. W. Geraets Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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P. Koen Bos Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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Johan van der Stok Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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Preoperative embolization of bone tumours was introduced by Feldman et al in 1975. 36 Following this report, the hypothesis that preoperative embolization of metastases reduces intraoperative blood loss was postulated by some authors during the 80s and 90s

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Julie J. Willeumier Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Yvette M. van der Linden Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Michiel A.J. van de Sande Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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P.D. Sander Dijkstra Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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a primary bone tumour until proven otherwise. Denying this possibility might deprive patients of correct and curative treatments. If the patient has no history of malignancy, a (PET-)CT scan of the chest and abdomen should be performed. In case no

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Zsombor Panti Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Mihai Nica Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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-sparing surgery dominates the modern management of primary malignant bone tumours. For the reconstruction of massive bone defects resulted after the resection of bone sarcoma standard nowadays is the use of modular endoprosthetic systems, performed usually in

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