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Christof Berberich Department of Medical Training and Education, Heraeus Medical GmbH, Wehrheim, Germany

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Pablo Sanz-Ruiz Department of Traumatology and Orthopaedic Surgery, General University Hospital Gregorio Marañón, Madrid, Spain

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-morbidities together with the increasing spread of resistant pathogens, prevention is gaining increasing importance. Peri-operative antibiotic prophylaxis during implant surgery is a recognized necessity. Further addition of local antibiotics eluting from bone cement

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.4.180104
Volume/Issue:
Volume 4: Issue 10
Open access
Claus Varnum The Danish Hip Arthroplasty Register
Department of Orthopaedic Surgery, Vejle Hospital, Vejle, Denmark

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Alma Bečić Pedersen Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark

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Ola Rolfson The Swedish Hip Arthroplasty Register
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Cecilia Rogmark The Swedish Hip Arthroplasty Register
Lund University, Skåne University Hospital, Department of Orthopedics, Malmö, Sweden

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Ove Furnes The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
Department of Clinical Medicine, University of Bergen, Bergen, Norway

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Geir Hallan The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
Department of Clinical Medicine, University of Bergen, Bergen, Norway

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Keijo Mäkelä The Finnish Arthroplasty Register
Department of Orthopaedics and Traumatology, Turku University Hospital, Turku, Finland

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Richard de Steiger Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), Adelaide, Australia
Department of Surgery, Epworth HealthCare, University of Melbourne, Melbourne, Australia

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Martyn Porter The National Joint Registry of England, Wales, Northern Ireland and Isle of Man
Centre for Hip Surgery, Wrightington Hospital, Wrightington, Wigan and Leigh NHS Trust, Lancashire, United Kingdom

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Søren Overgaard The Danish Hip Arthroplasty Register
Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark

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polyethylene liner. 25 , 26 Several bone cements were also identified as poorly performing after only three years of follow-up, especially the Boneloc cement and a low viscosity cement. 27 , 28 With a longer follow-up, three cemented implants

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.4.180091
Volume/Issue:
Volume 4: Issue 6
Open access
Geke A. W. Denissen Landelijke Registratie Orthopedische Implantaten (Dutch Arthroplasty Register), ’s Hertogenbosch, The Netherlands

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Liza N. van Steenbergen Landelijke Registratie Orthopedische Implantaten (Dutch Arthroplasty Register), ’s Hertogenbosch, The Netherlands

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Wouter T. Lollinga Landelijke Registratie Orthopedische Implantaten (Dutch Arthroplasty Register), ’s Hertogenbosch, The Netherlands

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Nico J. J. Verdonschot Dept. of Biomechanics, Radboud University Medical Center, Nijmegen, The Netherlands
Department of Biomechanical Engineering, University of Twente, Enschede, The Netherlands

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Berend W. Schreurs Landelijke Registratie Orthopedische Implantaten (Dutch Arthroplasty Register), ’s Hertogenbosch, The Netherlands
Dept. of Orthopaedics, Radboud University Medical Center, Nijmegen, The Netherlands

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Rob G. H. H. Nelissen Landelijke Registratie Orthopedische Implantaten (Dutch Arthroplasty Register), ’s Hertogenbosch, The Netherlands
Dept. of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands

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components) ( Table 1 ). For bone cement, the name of bone cement, the manufacturer, type of cement, viscosity, whether the cement contains any antibiotics and use of a vacuum cement mixing system are collected ( Table 2 ). In 2014, the process described

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.4.180063
Volume/Issue:
Volume 4: Issue 6
Open access
T. Fintan Moriarty AO Research Institute Davos, Switzerland

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Richard Kuehl University Hospital of Basel, Switzerland

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Tom Coenye Ghent University, Belgium

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Willem-Jan Metsemakers University Hospitals Leuven, Belgium

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Mario Morgenstern Trauma Centre, Murnau, Germany

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Edward M. Schwarz University of Rochester Medical Center, New York, USA

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Martijn Riool AMC, University of Amsterdam, The Netherlands

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Sebastian A.J. Zaat AMC, University of Amsterdam, The Netherlands

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Nina Khana University Hospital of Basel, Switzerland

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Stephen L. Kates Virginia Commonwealth University, Virginia, USA

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R. Geoff Richards AO Research Institute Davos, Switzerland

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the 1970s, when gentamicin-loaded bone cement was first tested in humans. 57 Bone cement was a convenient vehicle for antibiotic delivery, as it was routinely applied in cemented arthroplasties. Gentamicin was identified as a suitable antibiotic

Article Type:
Research Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.1.000037
Volume/Issue:
Volume 1: Issue 4
Open access
Heinz Winkler Osteitis Centre, Privatklinik Döbling Wien, Heiligenstaedter Strasse 57-63, A-1190 Wien, Austria

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delivering antibiotics by a local drug-delivery system was first followed by Buchholz et al, who mixed antibiotics and PMMA to create a local carrier. 25 From these findings, Klemm et al have developed techniques using antibiotic-loaded bone cement in

Article Type:
Research Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.2.160063
Volume/Issue:
Volume 2: Issue 5
Open access
M M Morlock Institute of Biomechanics, TUHH Hamburg University of Technology, Hamburg, Germany

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E Gomez-Barrena Department of Orthopaedic Surgery and Traumatology, Universidad Autónoma de Madrid, Madrid, Spain

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D C Wirtz Department of Orthopaedics and Traumatology, University Hospital Bonn, Bonn, Germany

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A Hart London Implant Retrieval Centre, Royal National Orthopaedic Hospital, Stanmore, UK

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J P Kretzer Department of Orthopaedic Surgery, Heidelberg University Hospital, Heidelberg, Germany

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failed systemically during their clinical use. These failures included corrosion-induced loosening of cemented titanium stems ( 4 ), mechanical breakdown of a polymethylmethacrylat (PMMA) bone cement due to problems with the glass transition temperature

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1530/EOR-22-0033
Volume/Issue:
Volume 7: Issue 6
Open access
Maria-Pau Ginebra Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgical Engineering, Universitat Politècnica de Catalunya (UPC), Spain

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Montserrat Espanol Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgical Engineering, Universitat Politècnica de Catalunya (UPC), Spain

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Yassine Maazouz Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgical Engineering, Universitat Politècnica de Catalunya (UPC), Spain
Mimetis Biomaterials, Spain

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Victor Bergez Mimetis Biomaterials, Spain

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David Pastorino Mimetis Biomaterials, Spain

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porous network of micrometric/nanometric CaP crystals ( Fig. 2 ). 27 Unlike in acrylic bone cements, widely used in orthopaedic surgery for arthroplasty fixation and vertebroplasty, the setting reaction in CPC is not exothermic, 28 and therefore

Article Type:
Research Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.3.170056
Volume/Issue:
Volume 3: Issue 5
Open access
Petra Izakovicova HELIOS Klinik Zerbst/Anhalt, Germany

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Olivier Borens Service of Orthopaedics and Traumatology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland

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Andrej Trampuz Charité – Universitätsmedizin Berlin, Corporate Member of Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Center for Musculoskeletal Surgery (CMSC), Berlin, Germany

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relates to high rates of contamination. In acute post-operative infections, sonicating parts of the implants that are covered with antibiotic-loaded bone cement may inhibit bacterial growth and lead to false negative results caused by increased antibiotic

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.4.180092
Volume/Issue:
Volume 4: Issue 7
Open access
Christoph H. Lohmann Department of Orthopeadic Surgery, Otto-von-Guericke University, Leipziger Str. 44,39120 Magdeburg, Germany

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Sanjiv Rampal Department of Orthopeadic Surgery, Otto-von-Guericke University, Leipziger Str. 44,39120 Magdeburg, Germany

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Martin Lohrengel Department of Orthopeadic Surgery, Otto-von-Guericke University, Leipziger Str. 44,39120 Magdeburg, Germany

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Gurpal Singh Division of Musculoskeletal Oncology, University Orthopaedics Hand and Reconstructive Microsurgery Cluster, National University Health System, 1E Kent Ridge Road, 119228 Singapore

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functionally equivalent to glenoid retroversion. Clinically, this is of relevance as significantly increased stress within the cement mantle and the glenoid bone as well as increased micromotion at the bone-cement interface has been associated with glenoid

Article Type:
Research Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.2.160058
Volume/Issue:
Volume 2: Issue 5
Open access
Sylvain Steinmetz Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Diane Wernly Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Kevin Moerenhout Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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Andrej Trampuz Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery (CMSC), Berlin, Germany

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Olivier Borens Service of Orthopaedics and Traumatology, Lausanne University Hospital, Lausanne, Switzerland

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polymethylmethacrylate bone cements and Staphylococcus aureus biofilm formation . Acta Orthop Scand 2000 ; 71 : 625 – 629 . 23. Zimmerli W Widmer AF Blatter M Frei R Ochsner PE ; Foreign-Body Infection (FBI) Study

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.4.180093
Volume/Issue:
Volume 4: Issue 7
Open access