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Önder İ. Kılıçoğlu Department of Orthopaedics and Traumatology, İstanbul University, Istanbul Faculty of Medicine, Turkey

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Mehmet Demirel Department of Orthopaedics and Traumatology, İstanbul University, Istanbul Faculty of Medicine, Turkey

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Şamil Aktaş Department of Underwater and Hyperbaric Medicine, İstanbul University, Istanbul Faculty of Medicine, Turkey

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bisphosphonate in the treatment of acute CN; 96 , 97 however, there is currently no compelling evidence to support the use of bisphosphonate in the medical management of CN. 96 Additionally, it has recently been discovered that the osteoclastogenic

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Sohail Yousaf Kingston Hospital NHS Foundation Trust, UK
University of Brighton, UK

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Edward J.C. Dawe Western Sussex Hospitals NHS Foundation Trust, UK
Brighton and Sussex Medical Schools, UK

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Alan Saleh Kingston Hospital NHS Foundation Trust, UK

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Ian R. Gill Kingston Hospital NHS Foundation Trust, UK

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Alex Wee Frimley Health NHS Foundation Trust, UK

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progression whilst maintaining bony architecture and preventing deformity. Antiresorptive drugs, in the form of oral bisphosphonates or intravenous pharmacological agents such as Pamidronate, have been used for the management of acute Charcot foot. However

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Michael J. Raschke Department of Trauma, Hand and Reconstructive Surgery, Westphaelian Wilhelms University Muenster, Waldeyer Strasse 1, 48149 Muenster, Germany

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Christoph Kittl Department of Trauma, Hand and Reconstructive Surgery, Westphaelian Wilhelms University Muenster, Waldeyer Strasse 1, 48149 Muenster, Germany

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Christoph Domnick Department of Trauma, Hand and Reconstructive Surgery, Westphaelian Wilhelms University Muenster, Waldeyer Strasse 1, 48149 Muenster, Germany

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, in some cases, with calcium) in these cases. Further post-operative osteological investigation of bone mineral density by DXA or qCT and of endocrine status is suggested to evaluate whether the addition of bisphosphonates or other medications may be

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Stefan Rammelt University Center of Orthopaedics & Traumatology, University Hospital Carl Gustav Carus, Dresden, Germany

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fractures. Treatment for manifest osteoporosis includes life style modifications (smoking and alcohol cessation, physical activity), vitamin D and calcium supplementation, and anti-resorptive drugs (bisphosphonates, raloxifene, denosumab). Promising new

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Hagen Fritzsche University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Anne Weidlich University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Klaus-Dieter Schaser University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Elisabeth Mehnert University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Doreen Winkler University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Stefan Rammelt University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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pattern is seen with often marked distension of the bone and thinning of the cortical bone. Conventional radiography and CT typically describe a milky glass-like change. Therapy for fibrous dysplasia is usually conservative. Bisphosphonates may be used if

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