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Jennette Higgs Food to Fit Ltd., PO Box 6057, Greens Norton, Northamptonshire, NN12 8GG, United Kingdom

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Emma Derbyshire Nutritional Insight Ltd., Surrey, KT17 2AA, United Kingdom

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Kathryn Styles Food to Fit Ltd., PO Box 6057, Greens Norton, Northamptonshire, NN12 8GG, United Kingdom

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. Previously, there has been a general tendency to focus on individual nutrients, or supplements, rather than a ‘whole diet’ approach. It is now well accepted that a healthy diet can help to prevent non-communicable diseases, such as osteoporosis, with

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G. Ulrich Exner Orthopaedie Zentrum Zuerich (ozz), Seestrasse 259, CH 8038 Zurich, Switzerland

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Michael O. Kurrer Gemeinschaftspraxis fuer Pathologie, Caecilienstrasse 3, CH 8032 Zurich, Switzerland

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Nadja Mamisch-Saupe Klinik Hirslanden, Department of Musculoskeletal Radiology, Witellikerstrasse 40, 8032 Zurich, Switzerland

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Stephen R. Cannon BMI The Clementine Churchill Hospital, Sudbury Hill, Harrow, Middlesex HA1 3RX, Great Britain

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literature review by Traina et al 1 outlines the general approach to performing biopsies of bone and soft tissue, respectively. As there is no single standard approach for biopsy for very different conditions, personal opinions and judgement influence

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T Gosens Department of Orthopedic and Trauma Surgery, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands
Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands

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B L den Oudsten Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands
Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands

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aspects and on the achieved function of a joint or the survival of a prosthesis, while a biopsychosocial approach addresses the needs of patients better and approaches them more holistically. The purpose of this instructional review is to alert

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Tristan Ferry Service de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)

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Jolien Onsea Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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Tiphaine Roussel-Gaillard Institut des Agents Infectieux, Centre de Biologie et de Pathologie du Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Cécile Batailler Service de Chirurgie Orthopédique et de Médecine du Sport, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Thomas Fintan Moriarty AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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, limited mobility, and a higher mortality rate compared to patients who do not develop this complication ( 3 , 6 ). Management concepts consist of a combined surgical and antibiotic treatment approach. Because these infections are biofilm

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Andrea Angelini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Nicolò Mosele Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Elisa Pagliarini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Diagnostic and treatment algorithm for Gorham–Stout disease. Radiotherapy and medical treatments play a very important role in the management of the disease, and many pharmacological approaches have been tried during the past years. Moderate doses

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Michael de Buys Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa

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Krisantha Moodley Emergency Department, ER Consulting, Johannesburg, South Africa

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Josip Nenad Cakic Department Orthopaedic Surgery, Life Fourways Hospital, Johannesburg, South Africa

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Jurek R T Pietrzak Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa

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rate approaching 40% ( 25 , 26 ). Colonization by S. aureus is a modifiable risk factor for SSI and carriers of S. aureus have a 9–10 times greater risk of developing SSI than non-carriers ( 27 , 28 ). MRSA colonization leads to four times greater

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Thomas M Grupp Aesculap AG, Research & Development & Medical Scientific Affairs, Tuttlingen, Germany
Ludwig Maximilians University Munich, Department of Orthopaedic and Trauma Surgery, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Munich, Germany

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Sabine Rusch Aesculap AG, Research & Development & Medical Scientific Affairs, Tuttlingen, Germany

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Philippe Massin CMC Ambroise-Paré-Hartmann, Neuilly-sur-Seine, France

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Ashley Blom National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, UK
Translational Health Sciences, Bristol Medical School, Musculoskeletal Research Unit, University of Bristol, Southmead Hospital, Bristol, UK

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Eduardo Garcia-Rey Hôpital Universitario La Paz-Idi Paz, Madrid, Spain
Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, Madrid, Spain

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Luca Cristofolini Department of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum - Università di Bologna, Bologna, Italy

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Dennis Janssen Radboud University Medical Center, Radboud Research Institute, Orthopaedic Research Lab, Nijmegen, the Netherlands

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Bernd Grimm Luxembourg Institute of Health, Human Motion, Orthopaedics, Sports Medicine & Digital Methods Group, Transversal Activities, Luxembourg

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Alexander Giurea Department of Orthopaedic Surgery, Medical University of Vienna, Vienna, Austria

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Marcus Jäger Department of Orthopaedics, Trauma & Reconstructive Surgery St. Marien Hospital Mülheim an der Ruhr & Chair of Orthopaedics and Trauma Surgery University of Duisburg–Essen, Essen, Germany

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Francesco Siccardi Medacta International SA, Research & Development & Medical Affairs, Castel San Pietro, Switzerland

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Søren Overgaard Copenhagen University Hospital, Department of Orthopaedic Surgery and Traumatology, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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patient associations, medical societies and regulatory agencies need to commit to working together in a collaborative approach to ensure the safety and efficacy of devices to improve patient health and quality of life ( 1 ). Objectives The objectives

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SaTia T. Sinclair Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Ahmed K. Emara Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Melissa N. Orr Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Kara M. McConaghy Case Western Reserve University School of Medicine, Cleveland, Ohio, United States

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Alison K. Klika Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Nicolas S. Piuzzi Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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and knee arthroplasty. Therefore, the purpose of this study was to review the comorbidity indices currently used in arthroplasty research to better understand their properties and potentially highlight the need for a consistent, data-driven approach

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Laura Stiegel Cleveland Clinic Department of Orthopaedic Surgery, Cleveland, Ohio, USA

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Alison K. Klika Cleveland Clinic Department of Orthopaedic Surgery, Cleveland, Ohio, USA

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Carlos A. Higuera Cleveland Clinic Department of Orthopaedic Surgery, Weston, Florida, USA

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Wael K.Barsoum Cleveland Clinic Department of Orthopaedic Surgery, Weston, Florida, USA

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Nicolas S. Piuzzi Cleveland Clinic Department of Orthopaedic Surgery, Cleveland, Ohio, USA

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undertaking of building a research team on their own. Each clinician’s needs will vary depending on the infrastructure already available in their practice or institution and how much time can be devoted to research. Nonetheless, a shared first approach is to

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Claus Varnum The Danish Hip Arthroplasty Register
Department of Orthopaedic Surgery, Vejle Hospital, Vejle, Denmark

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Alma Bečić Pedersen Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark

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Ola Rolfson The Swedish Hip Arthroplasty Register
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Cecilia Rogmark The Swedish Hip Arthroplasty Register
Lund University, Skåne University Hospital, Department of Orthopedics, Malmö, Sweden

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Ove Furnes The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
Department of Clinical Medicine, University of Bergen, Bergen, Norway

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Geir Hallan The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
Department of Clinical Medicine, University of Bergen, Bergen, Norway

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Keijo Mäkelä The Finnish Arthroplasty Register
Department of Orthopaedics and Traumatology, Turku University Hospital, Turku, Finland

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Richard de Steiger Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), Adelaide, Australia
Department of Surgery, Epworth HealthCare, University of Melbourne, Melbourne, Australia

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Martyn Porter The National Joint Registry of England, Wales, Northern Ireland and Isle of Man
Centre for Hip Surgery, Wrightington Hospital, Wrightington, Wigan and Leigh NHS Trust, Lancashire, United Kingdom

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Søren Overgaard The Danish Hip Arthroplasty Register
Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark

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routines, all hospital units immediately joined with a completeness at case level of 95%. 12 Early findings on surgical approaches and the risk of dislocation dramatically influenced the choice of surgical technique in favour of the direct lateral

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