Search for other papers by Alessandro Bensa in
Google Scholar
PubMed
Search for other papers by Alessandro Sangiorgio in
Google Scholar
PubMed
Search for other papers by Angelo Boffa in
Google Scholar
PubMed
Search for other papers by Manuela Salerno in
Google Scholar
PubMed
Search for other papers by Giacomo Moraca in
Google Scholar
PubMed
Applied and Translational Research (ATR) Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Università della Svizzera Italiana, Faculty of Biomedical Sciences, Lugano, Switzerland
Search for other papers by Giuseppe Filardo in
Google Scholar
PubMed
effective approach among the intra-articular treatment options for knee OA remains debated ( 26 , 27 ). In this scenario, an updated and comprehensive meta-analysis of randomized controlled trials (RCTs) comparing CS injections with HA and PRP approaches
Search for other papers by Silvia Valisena in
Google Scholar
PubMed
Search for other papers by Benjamin Azogui in
Google Scholar
PubMed
Search for other papers by Rémy S Nizard in
Google Scholar
PubMed
Search for other papers by Philippe M Tscholl in
Google Scholar
PubMed
Search for other papers by Etienne Cavaignac in
Google Scholar
PubMed
Search for other papers by Pierre-Alban Bouché in
Google Scholar
PubMed
Search for other papers by Didier Hannouche in
Google Scholar
PubMed
, since their divulgation, new randomized controlled trials have been published, prompting the need to provide an updated summary of available evidence. We conducted a systematic review and NMA on randomized controlled trials (RCT) on patients with knee
Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China
Search for other papers by Qiuyuan Wang in
Google Scholar
PubMed
Search for other papers by Feng Li in
Google Scholar
PubMed
Search for other papers by Yidan Yang in
Google Scholar
PubMed
Search for other papers by Chen Yue in
Google Scholar
PubMed
Department of Bone And Joint Diseases, Luoyang Orthopedic Hospital of Henan Province. Orthopedic Hospital of Henan Province, Luoyang, China
Search for other papers by Jiayi Guo in
Google Scholar
PubMed
entails drawing conclusions from meticulously conducted randomized controlled trials (RCTs) and meta-analyses that meet the highest contemporary scientific standards. Thus, we performed a systematic review and meta-analysis of RCTs to evaluate the impact
Search for other papers by Xinhuan Lei in
Google Scholar
PubMed
Search for other papers by Jie Xiang in
Google Scholar
PubMed
Search for other papers by Hailan Yang in
Google Scholar
PubMed
Search for other papers by Hongya Bao in
Google Scholar
PubMed
Search for other papers by Zhong Zhu in
Google Scholar
PubMed
Search for other papers by Hua Luo in
Google Scholar
PubMed
-analysis was registered on PROSPERO (registration no.: CRD42022362584). Inclusion criteria This study included randomized controlled trials (RCTs), cohort studies, or case–control studies. The study population comprised patients undergoing TKA. The
Search for other papers by Daniel J. McCormack in
Google Scholar
PubMed
Search for other papers by Darren Puttock in
Google Scholar
PubMed
Search for other papers by Steven P. Godsiff in
Google Scholar
PubMed
arthritis both in terms of clinical and cost effectiveness after comparing UKR to TKR. 15 The inclusion criteria for this multi-centre randomized controlled trial (RCT) were isolated full-thickness cartilage loss of the medial compartment tibia and
Department of Orthopaedic Surgery, University of Cape Town, South Africa
Search for other papers by Mark Anthony Roussot in
Google Scholar
PubMed
Search for other papers by Georges Frederic Vles in
Google Scholar
PubMed
Search for other papers by Sam Oussedik in
Google Scholar
PubMed
that reported clinical and/or radiological outcomes comparing KA and MA TKA. Case reports, letters, unpublished data, cadaver studies and studies of revision arthroplasty were excluded ( Fig. 3 ). Fig. 3 PRISMA Flow Diagram Note . RCT
Academic Department of Trauma and Orthopaedics, LGI, University of Leeds, Leeds, UK
Leeds Teaching Hospitals Trust, UK
Search for other papers by Sohail Nisar in
Google Scholar
PubMed
Search for other papers by Jeya Palan in
Google Scholar
PubMed
The Lister Hospital, Chelsea Bridge, London, UK
Centre de l’Arthrose - Clinique du Sport, Bordeaux-Mérignac, France
Search for other papers by Charles Rivière in
Google Scholar
PubMed
Search for other papers by Mark Emerton in
Google Scholar
PubMed
Leeds Teaching Hospitals Trust, UK
Search for other papers by Hemant Pandit in
Google Scholar
PubMed
implant with a femoral component that more closely restores the native trochlea anatomy may help improve patient outcomes. 44 , 45 A recent randomized-controlled trial (RCT), however, which also used the Vanguard implant, found no difference in any
Search for other papers by David Constantinescu in
Google Scholar
PubMed
Search for other papers by William Pavlis in
Google Scholar
PubMed
Search for other papers by Michael Rizzo in
Google Scholar
PubMed
Search for other papers by Dennis Vanden Berge in
Google Scholar
PubMed
Search for other papers by Spencer Barnhill in
Google Scholar
PubMed
Search for other papers by Victor Hugo Hernandez in
Google Scholar
PubMed
during hospitalization. The Cochrane Risk of Bias in Randomized Trials (RoB 2.0) and Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) tools were used to assess for risk of bias in randomized control trials (RCTs) and
Newcastle University, Newcastle upon Tyne, UK
Search for other papers by R J M Morrison in
Google Scholar
PubMed
University of York, York, UK
Search for other papers by W G Fishley in
Google Scholar
PubMed
The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
Search for other papers by K S Rankin in
Google Scholar
PubMed
University of York, York, UK
Search for other papers by M R Reed in
Google Scholar
PubMed
controlled trial (RCT) comparing a multivitamin tablet to placebo ( 13 ), one was an RCT comparing two different strengths of vitamin D supplementation on two primary endpoints ( 14 ), and the last was a non-randomised prospective cohort study ( 15 ). All
School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Search for other papers by Hsiao-Yi Cheng in
Google Scholar
PubMed
Department of Primary Care Medicine, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
Search for other papers by Chun-Wei Liang in
Google Scholar
PubMed
Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Search for other papers by Yu-Hao Lee in
Google Scholar
PubMed
Search for other papers by Timporn Vitoonpong in
Google Scholar
PubMed
Master’s Program in Long-Term Care, College of Nursing, Taipei Medical University, Taipei, Taiwan
Search for other papers by Chun-De Liao in
Google Scholar
PubMed
Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Search for other papers by Shih-Wei Huang in
Google Scholar
PubMed
, International Clinical Trials Registry Platform (ICTRP), and International Standard Randomised Controlled Trial Number registry (ISRCTN)) were searched for relevant clinical trials up to February 2024. Randomized controlled trials (RCTs) that examined ( 1 ) the