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Jacobien H.F. Oosterhoff Department of Orthopaedic Surgery, Amsterdam UMC, University of Amsterdam, the Netherlands
Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Job N. Doornberg Department of Orthopaedic Surgery, Amsterdam UMC, University of Amsterdam, the Netherlands
Department of Orthopaedic & Trauma Surgery, Flinders Medical Centre, Flinders University, Adelaide, SA, Australia

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Machine Learning Consortium Members of the Machine Learning Consortium: Paul Algra, Michel van den Bekerom, Mohit Bhandari, Michiel Bongers, Charles Court-Brown, Anne-Eva Bulstra, Geert Buijze, Sofia Bzovsky, Neil Chen, Job Doornberg, Andrew Duckworth, J. Carel Goslings, Benjamin Gravesteijn, Olivier Groot, Gordon Guyatt, Laurent Hendrickx, Dirk-Jan Hofstee, Frank IJpma, Ruurd Jaarsma, Stein Janssen, Paul Jutte, Aditya Karhade, Lucien Keijser, Gino Kerkhoffs, David Langerhuizen, Jonathan Lans, Wouter Mallee, Matthew Moran, Margaret McQueen, Marjolein Mulders, Miryam Obdeijn, Tarandeep Oberai, Jacobien H.F. Oosterhoff, Rudolf Poolman, David Ring, Paul Tornetta III, Joseph Schwab, Emil H. Schemitsch, Niels Schep, Inger Schipper, Bram Schoolmeesters, Marc Swiontkowski, David Sanders, Sheila Sprague, Ewout Steyerberg, Stephen D. Walter, Monique Walenkamp

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2019 ; 101 : 2167 – 2174 . 33. Wyles CC Tibbo ME Fu S et al. Use of natural language processing algorithms to identify common data elements in operative notes for total hip arthroplasty . J Bone Joint Surg Am

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A Frodl Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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N Geisteuer Department of Orthopedics and Traumatology, Asklepios Hospital Harburg, Hamburg, Germany

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A Fuchs Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany

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T Nymark Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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H Schmal Department of Orthopedics and Traumatology, Freiburg University Hospital, Freiburg, Germany
Department of Orthopedic Surgery, University Hospital Odense, Odense C, Denmark

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.92** 4 7 3 Stenqvist et al. (2) 309 192:117 ND ND  iNPWT 139 73.3 87:52 Prevena † 17 22  SWC 170 71.8 105:65 27 30 *Matched controls in subgroup – total: 5237, closed

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Andrew Carr Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK

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Arthroplasty Register founded in 1975 and the Swedish Hip Arthroplasty Register founded in 1979. Other Scandinavian countries then introduced registries during the 1980s and 1990s with more widespread use of registries occurring after the year 2000. These

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Tristan Ferry Service de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)

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Jolien Onsea Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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Tiphaine Roussel-Gaillard Institut des Agents Infectieux, Centre de Biologie et de Pathologie du Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Cécile Batailler Service de Chirurgie Orthopédique et de Médecine du Sport, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Thomas Fintan Moriarty AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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periprosthetic joint infection following total joint arthroplasty . Journal of Bone and Joint Surgery 2018 100 777 – 785 . ( https://doi.org/10.2106/JBJS.16.01435 ) 6 Moriarty TF Metsemakers WJ Morgenstern M Hofstee MI Vallejo Diaz A Cassat JE

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Paul L Rodham Academic Department of Trauma & Orthopaedics, Leeds General Infirmary, Leeds, United Kingdom of Great Britain and Northern Ireland

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Vasileios P Giannoudis Academic Department of Trauma & Orthopaedics, Leeds General Infirmary, Leeds, United Kingdom of Great Britain and Northern Ireland

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Nikolaos K Kanakaris Academic Department of Trauma & Orthopaedics, Leeds General Infirmary, Leeds, United Kingdom of Great Britain and Northern Ireland
Department of Trauma & Orthopaedics, University of Leeds, Leeds, United Kingdom of Great Britain and Northern Ireland

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Peter V Giannoudis Academic Department of Trauma & Orthopaedics, Leeds General Infirmary, Leeds, United Kingdom of Great Britain and Northern Ireland

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.1007/s13554-014-0013-5 ) 104. Ochi K Ikari K Naomi A & Momohara S . Administration of teriparatide treatment for a challenging case of nonunion of periprosthetic fracture after total knee arthroplasty . Archives of Osteoporosis 2013 8 159

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Enrique Gómez-Barrena Department of Orthopaedic Surgery and Traumatology, Hospital La Paz-IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain

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Christian Ehrnthaller Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Germany

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stabilization is the major intervention in its treatment ( 11 ). Epidemiology of non-unions The frequency of non-unions after acute long bone fractures is highly variable, classically reported between 5% and 10% of total long bone fractures. Recent

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Lars Nonnenmacher Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Maximilian Fischer Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Lyubomir Haralambiev Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Sander Bekeschus ZIK plasmatis, Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany

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Frank Schulze Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Georgi I Wassilew Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Janosch Schoon Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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Johannes C Reichert Center for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, Greifswald, Germany

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PJIs are known as a major complication after joint replacement. Periprosthetic infection rates range between 1.4% and 2.5% after primary joint arthroplasties ( 29 ) and up to 4% following revision arthroplasties ( 30 ). Current therapeutic strategies

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Joseph Genevière Faculty of Medicine, University of Geneva, Geneva, Switzerland
Co-first authors and equal contributors

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Shawna McCallin Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors

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Angela Huttner Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

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Truong-Thanh Pham Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Domizio Suva Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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patients with foot osteomyelitis. 8 Mortality remains high: surgical revisions of infected joint arthroplasties are associated with a fivefold increase in mortality compared to aseptic revisions. 9 In cases of treatment failure, there are few therapeutic

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Alan G. Fraser Department of Cardiology, University Hospital of Wales, Cardiff, UK

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Rob G.H.H. Nelissen Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands

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Per Kjærsgaard-Andersen Department of Orthopaedics, Vejle Hospital, South Danish University, Vejle, Denmark

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Piotr Szymański Centre of Postgraduate Medical Education, MSWiA Central Clinical Hospital, Warsaw, Poland

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Tom Melvin Healthcare Products Regulatory Authority, Earlsfort Terrace, Dublin 2, Ireland

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Paul Piscoi Health Technology Unit B6, Directorate General for Health (DG SANTE), European Commission, Brussels, Belgium

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On behalf of the CORE–MD Investigators (see Appendix) Alan Fraser, Piotr Szymański, Chris Gale, Aldo Maggioni, Elisabetta Zanon, Christina Dimopoulou, Cinzia Ceccarelli, Polyxeni Vairami, Anett Ruszanov, Per Kjærsgaard-Andersen, Rob Nelissen, Adrian Ott, Elizabeth Macintyre, Loredana Simulescu, Marieke Meijer, Berthold Koletzko, Sarah Wieczorek, Adamos Hadjipanayis, Stefano Del Torso, Perla Marang-van de Mheen, Lotje Hoogervorst, Ewout W. Steyerberg, Bas Penning De Vries, Peter McCulloch, Martin Landray, Daniel Prieto Alhambra, James Smith, Anne Lubbeke-Wolf, Stefan James, Sergio Buccheri, Robert Byrne, Laurna McGovern, Stephan Windecker, Andre Frenk, Georgios Siontis, Christoph Stettler, Arjola Bano, Lia Bally, Frank E. Rademakers, Jan D‘hooge, Anton Vedder, Elisabetta Biasin, Erik Kamenjasevic, Petra Schnell-Inderst, Felicitas Kühne, Ola Rolfson, Joel Jakobsson, Amanda Tornsö, Enrico G. Caiani, Lorenzo Gianquintieri, Cinzia Cappiello, Maristella Matera, Tom Melvin, Niall MacAleenan, Ria Mahon, Michèle Meagher, Gearóid McGauran, Thomas Wejs Møller, Ann-Sofie Sonne Holm-Schou, Jan Szulc, Robert E. Geertsma, Jantine W.P.M. van Baal, Joëlle M. Hoebert, Susana L.F. Cabaço, Paola Laricchiuta, Marina Torre, Filippo Boniforti, Eugenio Carrani, Stefania Ceccarelli, Claudia Wild, Sabine Ettinger, Juan Antonio Blasco Amaro, Juan Carlos Rejón Parrilla, Agnieszka Dobrzynska, David Epstein, Valentina Strammiello, Hannes Jarke, Kaisa Immonen, Françoise Schlemmer, Sabina Hoekstra, Marianna Mastroroberto, Christoph Ziskoven, Michael Hahn, Erman Melikyan, Richard Holborow, Suzanne Halliday, Alexey Shiryaev, Gero Viola, Harry van Vugt

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occluder – Leadless pacemaker – Subcutaneous implantable cardioverter defibrillator – Hip joint replacement (total hip cups, heads, liners and stems) – Knee joint replacement (total knee systems, unicompartmental knee systems) – Implantable continuous

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Juan Carlos Monllau Department of Orthopaedic Surgery, Hospital del Mar, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
ICATKnee, Institut Catalá de Traumatologia i Medicina de l’Esport (ICATME), Hospital Universitari Dexeus, UAB, Barcelona, Spain

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Simone Perelli Department of Orthopaedic Surgery, Hospital del Mar, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
ICATKnee, Institut Catalá de Traumatologia i Medicina de l’Esport (ICATME), Hospital Universitari Dexeus, UAB, Barcelona, Spain

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Giuseppe Gianluca Costa Orthopaedic Surgery Department, Ospedale Umberto I, Enna, Italy

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Cerulli-Mariani P Kalyvas J Pavlov H & Sculco TP . Patellofemoral evaluation after total knee arthroplasty. Validation of a new weight-bearing axial radiographic view . Journal of Bone and Joint Surgery. American Volume 2007 89 1810 – 1817

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