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insulin deficiency caused by damaged pancreatic B-cells, and type 2 diabetes mellitus due to insulin resistance resulting in defective insulin secretion ( 81 ). As it stands, DOP is due to deficiencies in glucose/insulin metabolism, the buildup of advanced
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at N-terminal sequence (NTS and site B) and one located at the interface between domains I and II (site A) identified so far ( 91 ). NTS was previously proposed to be the primary Co 2+ -binding site ( 95 , 96 , 97 , 98 ). However, current evidence
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incidence over time ( 2 ). Arthroscopic ACL reconstruction is the treatment of choice to restore knee stability ( 3 , 4 ) and to prevent secondary meniscal tears at long-term follow-up ( 5 , 6 ). However, the published meta-analysis showed that patients
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. Fig. 1 Funnel plot of primary total conventional hip replacement (excluding large-head metal-on-metal, all diagnoses, revision for prosthesis dislocation within 2 years). The Australian Orthopaedic Association has recommended access of a
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50 Custom uncemented vs 2 95 b off-the-shelf cemented 2 94 b Mid-term follow-up (3–10 years) Chow, 2015 46 Custom vs 69 61 a 6 (5 –7) 55 (20 –90
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.1302/2058-5241.6.210003 ) 33 Ziran B Cheung S Smith W & Westerheide K . Comparative efficacy of 2 different demineralized bone matrix allografts in treating long-bone nonunions in heavy tobacco smokers . American Journal of Orthopedics 2005 34 329 – 332 .
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image-free handheld robot for knee arthroplasty in bi-cruciate retaining total knee replacement . Health Sciences 2018 ; 2 : 98 – 101 . 24. Khare R Jaramaz B Hamlin B Urish KL . Implant orientation accuracy
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. 1 , 2 Their biomechanical forces on the hip implant are higher compared to the more elderly with THA, increasing the long-term failure rate of hip implants. 3 – 6 Failure of hip implants can be caused by periprosthetic bone loss, leading to aseptic
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infections (OR: 0.57, 95% CI: 0.35–0.93; P = 0.02, I 2 = 0%, low GRADE, Fig. 3A and Table 4 ) and periprosthetic joint infection (OR: 0.42, 95% CI: 0.33–0.54; P < 0.00001, I 2 = 1%, moderate GRADE, Fig. 3B and Table 4 ). The result of the
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is stable and no change of its position are observed. b) Note the symmetric radiolucency surrounding the distal stem with a sclerotic rim on the long-term control radiographs. Fig. 6 Radiological signs of subsidence of the P2 component two
