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Te-Feng Arthur Chou Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Hsuan-Hsiao Ma Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Shang-Wen Tsai Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Cheng-Fong Chen Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Po-Kuei Wu Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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Wei-Ming Chen Department of Orthopaedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Orthopaedics, School of Medicine, National Yang-Ming Chiao-Tung University, Taipei, Taiwan

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most recent meta-analysis was performed by Popat et al, but this study only included patients who underwent THA. 6 In this study, we performed a comprehensive review assessing the outcome of total knee arthroplasty (TKA) and total hip arthroplasty

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Elena Gálvez-Sirvent Department of Orthopaedic Surgery, “Infanta Elena” University Hospital, Valdemoro, Madrid, Spain
Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain

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Aitor Ibarzábal-Gil Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain

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E Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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). In early cases lasting less than 12 weeks ( 30 , 31 ), MUA may be considered. MUA is a simple and effective technique that has been shown to reduce stiffness and has been widely documented in cases of total knee arthroplasty (TKA) ( 30 , 32 , 33

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Peter van Schie Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Centre, Leiden, The Netherlands

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Shaho Hasan Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Leti van Bodegom-Vos Department of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Centre, Leiden, The Netherlands

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Jan W Schoones Walaeus Library, Leiden University Medical Centre, Leiden, The Netherlands

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Rob G H H Nelissen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Perla J Marang-van de Mheen Department of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Centre, Leiden, The Netherlands

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, leaving 33 papers and 8 arthroplasty reports to be included ( Fig. 1 ). Figure 1 PRISMA 2020 flowchart. THA, total hip arthroplasty; TKA, total knee arthroplasty. Risk of bias Thirty-two cohort studies and 1 controlled before

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Shaho Hasan Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Peter van Schie Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, The Netherlands

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Bart L Kaptein Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Jan W Schoones Walaeus Library, Leiden University Medical Centre, Leiden, The Netherlands

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Perla J Marang-van de Mheen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Safety & Security Science, Delft University of Technology, Delft, The Netherlands

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Rob G H H Nelissen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Introduction Aseptic loosening is the leading cause for revision of total hip and total knee arthroplasties (THAs/TKAs) reported in national arthroplasty registries ( 1 , 2 ). Aseptic loosening may have a multitude of causes including factors

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Richard Peter Almeida Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Lipalo Mokete Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Nkhodiseni Sikhauli Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Allan Roy Sekeitto Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Jurek Pietrzak Arthroplasty Unit, Division of Orthopaedic Surgery, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa

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Introduction Primary total joint arthroplasty (TJA), including total hip arthroplasty (THA) and total knee arthroplasty (TKA), are highly successful, reproducible surgical procedures. The demand for TJA is increasing globally, with projections

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Salvi Prat-Fabregat Hospital Clinic of Barcelona, Spain

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Pilar Camacho-Carrasco Hospital Clinic of Barcelona, Spain

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total knee arthroplasty (TKA) when compared with a matched cohort population. 42 This risk is related to age and to the complexity of the fracture. Knee instability or malunion increases the need for a TKA. 43 Some authors 44 , 45 suggest

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E Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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Alberto D Delgado-Martínez Department of Orthopaedic Surgery, Hospital Universitario de Jaén, Jaén, Spain
Department of Surgery, University of Jaén, Jaén, Spain

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Javier De Andrés-Ares Department of Anesthetics, Pain Unit, La Paz University Hospital, Madrid, Spain

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-rich plasma). Ultimate long-term pain alleviation treatment involves total knee arthroplasty (TKA). The management algorithm for knee OA also includes treating pain until an individual is suitable for TKA. Moreover, approximately 20% of individuals experience

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Hamid Rahmatullah Bin Abd Razak Department of Bioengineering, Imperial College London, London, UK
Sengkang General Hospital, Singapore
Joint first authors

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Daniel Chew Faculty of Medicine, Imperial College London, London, UK
Joint first authors

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Zepur Kazezian Department of Bioengineering, Imperial College London, London, UK

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Anthony M.J. Bull Department of Bioengineering, Imperial College London, London, UK

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progression of mechanical disruption. Other surgical options include arthroscopic debridement, cartilage resurfacing surgery and unicompartmental or total knee arthroplasty. 29 – 31 Is total knee arthroplasty the universal solution? In recent times

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Patrick Butler Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark

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Josef Gorgis Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark

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Bjarke Viberg Department of Orthopaedic Surgery and Traumatology, Kolding Hospital – part of Hospital Lillebaelt, Kolding, Denmark
Department of Regional Health Research, University of Southern Denmark, Odense, Denmark

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Søren Overgaard Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark

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might also be associated with an increased revision rate. Of note, Hallan et al 13 showed this in an unpublished study involving total knee arthroplasty (TKA). In their report, the shift in the use of well-documented implants was caused by a tender

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Philip F. Dobson Trauma and Orthopaedic Surgery, Royal Victoria Infirmary, Newcastle, UK

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Michael R. Reed Trauma and Orthopaedic Surgery, Royal Victoria Infirmary, Newcastle, UK

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) and total knee arthroplasty (TKA) at three hospitals within our institution, comparing standard sutures and triclosan-coated sutures. We established an infection rate of 0.8% in the control group and 0.7% in the intervention group, although our

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