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David Eckerdal Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden
Department of Clinical Sciences - Orthopedics, Lund University, Lund, Sweden

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Hendrik Pakosta Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden

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Muhanned Ali Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden
Department of Clinical Sciences - Orthopedics, Lund University, Lund, Sweden

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Isam Atroshi Department of Orthopedics, Hässleholm-Kristianstad Hospitals, Hässleholm, Sweden
Department of Clinical Sciences - Orthopedics, Lund University, Lund, Sweden

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results of an RCT is directly dependent on the design and conduct of the trial. The RCTs comparing collagenase injection with PNF have reported results implying similar treatment efficacy, durability, and complications ( 2 , 9 , 10 , 11 , 12 ). We

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Carlos A. Encinas-Ullán Department of Orthopaedic Surgery, ‘La Paz’ University Hospital-IdiPaz, Spain

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, ‘La Paz’ University Hospital-IdiPaz, Spain

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Introduction Understanding the anatomy of the medial side of the knee is essential for a correct diagnosis and treatment of isolated medial collateral ligament (MCL) tears. Conservative treatment of these lesions usually provides good results

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Giorgio Maria Calori ASST-Pini-CTO, University of Milan, Orthopaedic Reparative Surgery Department, Milan, Italy

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Emilio Mazza ASST-Pini-CTO, University of Milan, Orthopaedic Reparative Surgery Department, Milan, Italy

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Alessandra Colombo ASST-Pini-CTO, University of Milan, Orthopaedic Reparative Surgery Department, Milan, Italy

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Simone Mazzola ASST-Pini-CTO, University of Milan, Orthopaedic Reparative Surgery Department, Milan, Italy

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Massimiliano Colombo ASST-Pini-CTO, University of Milan, Orthopaedic Reparative Surgery Department, Milan, Italy

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biotechnologies implanted via CD. Materials and methods The PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) were followed to perform this systematic review of the literature and to present the results. 18 A

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Elisa Pala Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Giulia Trovarelli Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Andrea Angelini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Maria Chiara Cerchiaro Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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% complete healing for all sclerotherapy and embolization treatments; they also found a 3.4% recurrence rate. However, they found high heterogeneity and much variation in the results between the studies analyzed. Surgery Open surgery with curettage

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Daniel Kotrych Department of Orthopedics, Traumatology and Orthopedic Oncology, Pomeranian Medical University, Szczecin, Poland

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Andrea Angelini Department of Orthopedics and Orthopedic Oncology, University of Padova, Italy

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Andrzej Bohatyrewicz Department of Orthopedics, Traumatology and Orthopedic Oncology, Pomeranian Medical University, Szczecin, Poland

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Italy

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surgical techniques allows demanding reconstructions ( 19 , 20 , 21 , 22 ). With the use of CAS and custom 3D-printed reconstructions, satisfactory results in terms of functional and oncological outcomes have been also reported in recent series of

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Young Yi Department of Orthopaedic Surgery, Inje University, Seoul Paik Hospital, 85, 2-ga, Jeo-dong, Jung-gu, Seoul, 100-032, Republic of Korea

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Woochun Lee Seoul Foot and Ankle Center, Dubalo Orthopaedic Clinic, 764-30, Bang bae dong, Seochogu, Seoul, 06554, Republic of Korea.

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arthritis with minimal talar tilt. However, these approaches give unpredictable results in cases of more advanced ankle arthritis. 2 Total ankle arthroplasty or arthrodesis are performed for end-stage ankle arthritis. Ankle arthrodesis provides pain

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Joris Duerinckx Ziekenhuis Oost-Limburg, Genk, Belgium

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Frederik Verstreken Monica Hospital, Antwerp, Belgium

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would provide a better outcome. Some of the newer generation implants have stood the test of time, and successful clinical results have been published, making them a valid treatment alternative ( 3 ). This has provoked a growing interest in these

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Giuseppe Solarino Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Giovanni Vicenti Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Massimiliano Carrozzo Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Guglielmo Ottaviani Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Biagio Moretti Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Luigi Zagra IRCCS Istituto Ortopedico Galeazzi, Hip Department, Milan, Italy

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) Are the index test results interpreted by an examiner without the knowledge of the reference tests results? A study is considered as a high-quality study if it has < 1 flaw, as a moderate-quality study if it has ≥ 1 and < 2 flaws, as a low

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Serkan Bayram Department of Orthopedics and Traumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

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Ahmet Salduz Department of Orthopedics and Traumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

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Ahmet Müçteba Yıldırım Department of Orthopedics and Traumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

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Korhan Özkan Department of Orthopedics and Traumatology, Istanbul Medeniyet University, Istanbul Faculty of Medicine, Istanbul, Turkey

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Levent Eralp Department of Orthopedics and Traumatology, Retired Professor of Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

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Harzem Özger Department of Orthopedics and Traumatology, Retired Professor of Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

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reports, unpublished studies, animal experimental studies, articles posted on preprint servers, studies evaluating PMMA treatment results in regions other than the knee, those evaluating bone grafting for the treatment of benign aggressive bone tumor

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Mario Herrera-Pérez Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain
School of Medicine, Universidad de La Laguna, Tenerife, Spain

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Pablo Martín-Vélez Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain

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David González-Martín Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain
School of Medicine, Universidad de La Laguna, Tenerife, Spain

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Miguel Domínguez-Meléndez Foot and Ankle Unit, Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain

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Ahmed E Galhoum Specialty Doctor Trauma and Orthopaedics, George Eliot Hospital NHS Trust, Nuneaton, UK

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Victor Valderrabano Schmerzklinik, Basel, Switzerland
University of Basel, Basel, Switzerland

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Sergio Tejero Foot and Ankle Unit, Hospital Universitario Virgen del Rocío, Sevilla, Spain
School of Medicine, Universidad de Sevilla, Sevilla, Spain

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Introduction Low-energy fractures result from mechanical forces that would not ordinarily result in fracture, also known as ‘low-energy’ trauma, such as those equivalent to a fall from a standing height or less. These are fractures strongly

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