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Donald J. Davidson Research Department of Orthopaedics and Musculoskeletal Sciences, University College London, London, UK
Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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David Spratt Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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Alexander D. Liddle Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK
MSK Lab, Imperial College London, London, UK

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centred on finding a balance between efficacy and toxicity of silver; however, silver coatings have demonstrated efficacy and safety in clinical studies in the use of megaprostheses (which represent a useful model given their high overall rate of infection

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Ahmed Mabrouk Mid Yorkshire Teaching Hospitals, Yorkshire, United Kingdom
Institut du mouvement et de l’appareil locomoteur, Marseille, France

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Jae-Sung An Institut du mouvement et de l’appareil locomoteur, Marseille, France

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Kristian Kley Orthoprofis Hannover, Hannover, Germany

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Komal Tapasvi The Orthopaedic Speciality Clinic, Pune, India

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Sachin Tapasvi The Orthopaedic Speciality Clinic, Pune, India

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Matthieu Ollivier Institut du mouvement et de l’appareil locomoteur, Marseille, France

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.4% >1/3 resected, P < 0.001). A year later, the same group of authors, Faber et al. 2021 ( 10 ), assessed the clinical efficacy of the combined procedures in 440 patients over 3 years of follow-up. The group of patients who had additional HTO

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Chengxin Xie Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Liwei Zhang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Dehua Zhang Department of Emergency, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Lingjian Tao Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yong Zhao Department of Orthopedics, Shanghai Fengxian District Central Hospital, Shanghai 201400, China.

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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. Efficacy and safety of vancomycin for local application in the prevention of prosthetic joint infection . Practical Pharmacy and Clinical Remedies 2017 20 1152 – 1155 . ( https://doi.org/10.14053/j.cnki.ppcr.201710012 ) 34 Li X & Ding H . Clinical

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Mario Herrera-Pérez Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain
Department of Surgery, Universidad de La Laguna, Tenerife, Spain

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Victor Valderrabano Foot and Ankle Unit, Orthopaedic Department, Schmerzklinik, Basel, Switzerland
University of Basel, Basel, Switzerland

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Alexandre L Godoy-Santos Orthopaedic Department, Hospital Israelita, Sao Paulo, Brazil

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César de César Netto Director of the UIOWA Orthopedic Functional Imaging Research Laboratory (OFIRL), Iowa, USA
Department of Orthopedic and Rehabilitation, University of Iowa, Iowa, USA

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David González-Martín Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain
Department of Surgery, Universidad de La Laguna, Tenerife, Spain

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Sergio Tejero Foot and Ankle Unit, Hospital Universitario Virgen del Rocío, Sevilla, Spain
Department of Surgery, Universidad de Sevilla, Sevilla, Spain

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-term studies to determine its long-term efficacy ( 73 ). Bipolar allograft Designed with the idea of replacing the ankle joint with a fresh total allograft (fixed to the distal tibia and talus with screws), it is a novel and complex procedure. Clinical

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Rajpal Nandra Health Education West Midlands, Birmingham, UK

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Alan F. Brockie Academic Department of Military Nursing, Birmingham, UK

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Faisal Hussain Royal Orthopaedic Hospital, Birmingham, UK

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Introduction Healthcare research is undertaken to advance treatment of human disease. In the absence of such research, the efficacy of disease treatments would undoubtedly plateau. Innovation to enhance treatment requires scientific method

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Manuel Monteagudo Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Pilar Martínez de Albornoz Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Borja Gutierrez Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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José Tabuenca Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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Ignacio Álvarez Orthopaedic Foot and Ankle Unit, Hospital Universitario Quironsalud Madrid, Spain; Faculty of Medicine, UEM Madrid, Spain

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prospective, randomized, double-blinded study compared two calf-stretching regimens for PF and it was confirmed that Achilles stretching alone was an effective treatment. 53 Several Level-I and Level-II clinical studies demonstrate the efficacy of home

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Mahmut Nedim Doral Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Department of Sports Medicine, Ankara, Turkey

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Onur Bilge Konya N.E. University, Meram Faculty of Medicine, Department of Orthopaedics and Traumatology, Department of Sports Medicine, Konya, Turkey

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Gazi Huri Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey

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Egemen Turhan Hacettepe University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey

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René Verdonk Ghent University, Faculty of Medicine, Department of Orthopaedics and Traumatology, De Pintelaan, Ghent, Belgium

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implants. These procedures can be performed arthroscopically, as described previously. 78 Regarding clinical efficacy, good mid-term and long-term clinical outcomes of polyurethane-based scaffolds and CMI were recently reported. 82 - 85 Currently

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Enrique Gómez-Barrena Department of Orthopaedic Surgery and Traumatology, Hospital La Paz-IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain

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Christian Ehrnthaller Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Germany

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of clinical trials, despite solid proofs of safety and early efficacy. Figure 3 Intraoperative images of an atrophic tibia non-union. After debridement (A) with visible intramedullary nail and after insertion of a combination of autologous MSCs

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Alli Gokeler University of Groningen, University Medical Center Groningen, Center for Human Movement Science, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands

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Bart Dingenen Rehabilitation Research Institute, Biomedical Research Institute, Faculty of Medicine and Life Sciences, UHasselt, Diepenbeek, Belgium

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Caroline Mouton Département de l’Appareil Locomoteur, Centre Hospitalier de Luxembourg – Clinique d’Eich, 76, rue d’Eich, L-1460 Luxembourg, Luxembourg

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Romain Seil Département de l’Appareil Locomoteur, Centre Hospitalier de Luxembourg – Clinique d’Eich, 76, rue d’Eich, L-1460 Luxembourg, Luxembourg and Sports Medicine Research Laboratory, Luxembourg Institute of Health, 76, rue d’Eich, L-1460 Luxembourg, Luxembourg

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importance of establishing registries on a national basis has been advocated by Scandinavian authors to analyse the outcome after ALCR. 9 , 10 In many European countries, such registries are not available. Following these recommendations, clinical

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Xiangji Dang Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, P.R. China
Department of Pharmaceutical, Lanzhou University Second Hospital, Lanzhou, Gansu province, P.R. China

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Mei Liu The First Clinical Medical School, Gansu University of Chinese Medicine, Gansu, P.R. China

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Qiang Yang Department of Neurosurgery, Lanzhou University Second Hospital, Lanzhou, Gansu province, P.R. China

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Jin Jiang Department of Orthopedics, Lanzhou University Second Hospital, Lanzhou, Gansu province, P.R. China

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Yan Liu Gansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, Lanzhou, P.R. China

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Hui Sun Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, Gansu province, P.R. China

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Jinhui Tian Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, P.R. China

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accident, and transient ischemic attack ( 5 ). This systematic review and meta-analysis were designed to evaluate the efficacy and safety of TXA in high-risk patients undergoing TJA, aiming to guide the future TJA surgery clinical treatment program

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