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T. Fintan Moriarty AO Research Institute Davos, Switzerland

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Richard Kuehl University Hospital of Basel, Switzerland

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Tom Coenye Ghent University, Belgium

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Willem-Jan Metsemakers University Hospitals Leuven, Belgium

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Mario Morgenstern Trauma Centre, Murnau, Germany

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Edward M. Schwarz University of Rochester Medical Center, New York, USA

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Martijn Riool AMC, University of Amsterdam, The Netherlands

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Sebastian A.J. Zaat AMC, University of Amsterdam, The Netherlands

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Nina Khana University Hospital of Basel, Switzerland

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Stephen L. Kates Virginia Commonwealth University, Virginia, USA

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R. Geoff Richards AO Research Institute Davos, Switzerland

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ODRIs are Staphylococci. 13 - 17 Staphylococcus (S.) aureus accounts for between 20% and 30% of cases of infection after fracture fixation and prosthetic joint infections (PJI), with coagulase-negative staphylococci (CoNS) accounting for 20

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Ismail Remzi Tözün Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Vahit Emre Ozden Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Goksel Dikmen Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Kayahan Karaytuğ Department of Orthopaedic Surgery and Traumatology, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Acibadem Maslak Hospital, Sarıyer/Istanbul, Turkey

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Parvizi J . Infection burden for hip and knee arthroplasty in the United States . J Arthroplasty 2008 ; 23 : 984 – 991 . 4. Kurtz SM Ong KL Lau E Bozic KJ Berry D Parvizi J . Prosthetic

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Pier F. Indelli Department of Orthopaedic Surgery, Stanford University, Stanford, California, USA

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Stefano Ghirardelli IRCCS, Istituto Ortopedico Galeazzi, Milan, Italy

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Bruno Violante IRCCS, Istituto Ortopedico Galeazzi, Milan, Italy

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Derek F. Amanatullah Department of Orthopaedic Surgery, Stanford University, Stanford, California, USA

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detected by culture. Street et al sequenced sonication fluid from infected orthopaedic implants, including prosthetic devices, and showed that mNGS had 88% species-level sensitivity versus sonication fluid culture. 55 Huang et al, in a consecutive

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Joseph Genevière Faculty of Medicine, University of Geneva, Geneva, Switzerland
Co-first authors and equal contributors

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Shawna McCallin Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors

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Angela Huttner Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

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Truong-Thanh Pham Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Domizio Suva Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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treatment modalities used for phage application. In all but two cases reviewed here, PT was administered via the topical route, either by application of phages during/at the end of surgery directly or as an antimicrobial coating on prosthetic material, or

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Philippe Neyret President of EFORT

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Pierre Hoffmeyer Editor-in-Chief, EFORT Open Reviews

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singular. The papers of Senköylu et al. 2 and Kärrholm et al. 3 address specific entities, scoliosis and hip prosthetics respectively. They illustrate the varied solutions and provide insight into possible harmonisation applied to these conditions

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Catalin Cirstoiu Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Bogdan Cretu Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Sergiu Iordache Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Mihnea Popa Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Bogdan Serban Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Adrian Cursaru Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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with this plate that also failed. (B) Intraoperative resected segment and prosthetic measurements. (C) Postoperative X-ray after resection and reconstruction with a long modular fluted stem. Failure of prosthetic fixation may result when tumor

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Josep Muñoz Vives Hospital Nostra Senyora de Meritxell, Andorra, Spain

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Jean-Christophe Bel Hospices Civils de Lyon, Lyon, France

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Arantxa Capel Agundez Hospital Universitario 12 de Octubre, Madrid, Spain

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Francisco Chana Rodríguez Hospital General Universitario Gregorio Marañón, Madrid, Spain

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José Palomo Traver Hospital General de Castelló, Castelló de la Plana, Spain

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Morten Schultz-Larsen Odense Universitetshospita, Odense, Denmark

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Theodoros Tosounidis Leeds General Infirmary, Leeds, UK

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situations. Peri-prosthetic fractures around the knee are on the rise. The distal femur is most commonly affected, followed by the proximal tibia and the patella. Peri-prosthetic fractures involving both the distal femur and proximal tibia have been

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Mattia Loppini Department of Biomedical Sciences, Humanitas University, Italy; Hip Diseases and Joint Replacement Surgery Unit, Humanitas Clinical and Research Center, Italy

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Guido Grappiolo Hip Diseases and Joint Replacement Surgery Unit, Humanitas Clinical and Research Center, Italy

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evaluated the incidence of thigh pain, reporting no cases of severe or disabling thigh pain in the patient-administered questionnaire. The mean intra-operative peri-prosthetic fracture rate was 0.7% (0% to 2.4%) in 556 hips. 33 – 36 In one study of 250

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Massimo Ceruso Hand Surgery Unit, Centro Traumatologico Ortopedico, Azienda Ospedliero-Universitaria Careggi, Florence, Italy

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Sandra Pfanner Hand Surgery Unit, Centro Traumatologico Ortopedico, Azienda Ospedliero-Universitaria Careggi, Florence, Italy

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Christian Carulli Orthopaedic Clinic, University of Florence, Florence, Italy

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Introduction Until the late 1980s, finger joint prosthetic reconstruction had been almost exclusively performed by using monobloc silicone spacers as developed by Swanson et al more than 20 years previously. 1 Such implants are not fixed

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Colby Foster Department of Orthopaedic Surgery, Michigan Medicine, Ann Arbor, Michigan, USA

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Christopher Posada Department of Orthopaedic Surgery, Michigan Medicine, Ann Arbor, Michigan, USA
Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA

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Bryan Pack River Valley Orthopaedics/Orthopaedic Associates of Michigan, Grand Rapids, Michigan, USA

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Brian R. Hallstrom Department of Orthopaedic Surgery, Michigan Medicine, Ann Arbor, Michigan, USA

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Richard E. Hughes Department of Orthopaedic Surgery, Michigan Medicine, Ann Arbor, Michigan, USA
Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA
Department of Industrial & Operations Engineering, University of Michigan, Michigan, USA

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Introduction Evidence-based medicine is central to providing the highest quality care to total knee arthroplasty (TKA) patients. Patients have many types of outcomes, including infection, venous thromboembolism, death, readmission, peri-prosthetic

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