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Martin McNally The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Irene Sigmund The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK
Department of Orthopaedics and Trauma Surgery, Medical University of Vienna, Austria

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Andrew Hotchen The Bone infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Ricardo Sousa Porto Bone and Joint Infection Group (GRIP), Department of Orthopaedics, Centro Hospitalar Universitario Santo António and CUF-Hospitais e Clinicas, Portugal

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harvested, each with separate instruments ( 9 , 42 ). Specimens of bone–implant interface, periarticular membranes and synovium, are recommended. Infection is not uniformly distributed in the joint and multiple representative sites should be sampled ( 43

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1530/EOR-23-0044
Volume/Issue:
Volume 8: Issue 5
Open access
Chengxin Xie Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Wenjun Pan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Shouli Wang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xueli Yan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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histologic findings from joint tissue ( 4 ). Infection can lead to prosthesis loosening, bone defects and even life-threatening conditions in severe cases ( 5 ). With advances in surgical techniques and improvements in surgical conditions, PJI currently

Article Type:
Systematic Review
Category:
Knee
DOI:
https://doi.org/10.1530/EOR-23-0147
Volume/Issue:
Volume 9: Issue 6
Open access
Elizabeth K Tissingh The Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK
King’s Global Health Partnerships, School of Life Course and Population Sciences, King’s College London, London, UK

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Leonard Marais Department of Orthopaedic Surgery, School of Clinical Medicine, University of KwaZulu-Natal, KwaZulu-Natal, South Africa

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Antonio Loro Comprehensive Rehabilitation Services for People with Disability in Uganda (CoRSU) Hospital, Kisubi, Uganda

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Deepa Bose University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Nilo T Paner Department of Orthopaedics, University of the Philippines, Philippine General Hospital Manila, The Phillipines

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Jamie Ferguson The Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK
Department of Orthopaedics, University of the Philippines, Philippine General Hospital Manila, The Phillipines

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Mario Morgensten Centre for Musculoskeletal Infections, Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Basel, Switzerland

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Martin McNally The Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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previously surrounded terms such as postoperative or post-traumatic osteomyelitis, surgical site infection and infection following fracture fixation. Figure 1 outlines the diagnosis of FRI with confirmatory and suggestive criteria. Alongside this are

Article Type:
Review Article
Category:
Trauma
DOI:
https://doi.org/10.1530/EOR-22-0031
Volume/Issue:
Volume 7: Issue 6
Open access
Tristan Ferry Service de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)

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Jolien Onsea Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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Tiphaine Roussel-Gaillard Institut des Agents Infectieux, Centre de Biologie et de Pathologie du Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Cécile Batailler Service de Chirurgie Orthopédique et de Médecine du Sport, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Thomas Fintan Moriarty AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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, limited mobility, and a higher mortality rate compared to patients who do not develop this complication ( 3 , 6 ). Management concepts consist of a combined surgical and antibiotic treatment approach. Because these infections are biofilm

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1530/EOR-24-0042
Volume/Issue:
Volume 9: Issue 5
Open access
Andreas F. Mavrogenis First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Panayiotis D. Megaloikonomos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Thekla Antoniadou First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Vasilios G. Igoumenou First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Georgios N. Panagopoulos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Leonidas Dimopoulos First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Konstantinos G. Moulakakis Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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George S. Sfyroeras Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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Andreas Lazaris Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece

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glucose control. Treatment Revascularization, surgical and conservative wound debridement, and eradication of the infection are the principal aims of DFU treatment. The essential steps to preserve a moist, non-infected wound are to: 1

Article Type:
Research Article
Category:
Foot & Ankle
DOI:
https://doi.org/10.1302/2058-5241.3.180010
Volume/Issue:
Volume 3: Issue 9
Open access
Hee-Nee Pang Department of Orthopaedic Surgery, Singapore General Hospital, Singapore and Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Hamid Rahmatullah Bin Abd Razak Department of Orthopaedic Surgery, Singapore General Hospital, Singapore

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Stephen Petis Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Douglas D. R. Naudie Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Steven J. MacDonald Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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replacement . BMC Musculoskelet Disord 2013 ; 14 : 222 . 24 Leone JM , Hanssen AD . Management of infection at the site of a total knee arthroplasty . J Bone Joint Surg [Am] 2005 ; 87-A : 2335 - 2348 . 25 Tsukayama

Article Type:
Review Article
Category:
Knee
DOI:
https://doi.org/10.1302/2058-5241.2.160049
Volume/Issue:
Volume 2: Issue 3
Open access
Abdel Rahim Elniel Leeds Teaching Hospitals Trust, UK

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Peter V. Giannoudis Academic Department of Trauma and Orthopaedics, Leeds Teaching Hospitals, University of Leeds, UK; NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, UK

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of future infection. 22 , 23 Surgical debridement is considered one of the most important procedures for open lower limb fractures. 22 , 23 , 25 Traditionally, debridement has been performed within 6 hours of presentation. The rationale

Article Type:
Research Article
Category:
Trauma
DOI:
https://doi.org/10.1302/2058-5241.3.170072
Volume/Issue:
Volume 3: Issue 5
Open access
Elena Gálvez-Sirvent Department of Orthopaedic Surgery, “Infanta Elena” University Hospital, Valdemoro, Madrid, Spain
Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain

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Aitor Ibarzábal-Gil Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain

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E Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, “La Paz” University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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. Clinical resolution of infection occurred after an average of 3.3 additional procedures ( 55 ). In 2000 patients treated with ORIF by henkelman et al. in 2020, the rate of surgical site infection was 4.7% (93/2000) ( 56 ). In 2022, the rate of deep

Article Type:
Review Article
Category:
Knee
DOI:
https://doi.org/10.1530/EOR-22-0004
Volume/Issue:
Volume 7: Issue 8
Open access
AliSina Shahi The Rothman Institute at Thomas Jefferson University, Philadelphia, USA

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Javad Parvizi The Rothman Institute at Thomas Jefferson University, Philadelphia, USA

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Introduction Periprosthetic joint infection (PJI) is responsible for 25% of failed total knee arthroplasties 1 and 15% of revision total hip arthroplasties. 2 PJI has a huge economic burden on the health care system, and there will

Article Type:
Research Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1302/2058-5241.1.160019
Volume/Issue:
Volume 1: Issue 7
Open access
Yangqi Xu Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia

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Tony B Huang Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia

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Michael A Schuetz Jamieson Trauma Institute, Metro North Hospital and Health Service, Queensland Health, Brisbane, Queensland, Australia
Department of Orthopaedic Surgery, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia
Queensland University of Technology (QUT), Brisbane, Queensland, Australia

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Peter F M Choong Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia
Department of Orthopaedics, St. Vincent’s Hospital, Fitzroy, Victoria, Australia

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the ICARAUS group
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the ICARAUS group

Barrack RL & Nunley RM . Decreased hospital costs and surgical site infection incidence with a universal decolonization protocol in primary total joint arthroplasty . Journal of Arthroplasty 2017 32 728 – 734.e1 . ( https://doi.org/10.1016/j

Article Type:
Review Article
Category:
General Orthopaedics
DOI:
https://doi.org/10.1530/EOR-23-0078
Volume/Issue:
Volume 8: Issue 9
Open access