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Timothy Lording Melbourne Orthopaedic Group and The Alfred Hospital, Australia

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Sébastien Lustig Albert Trillat Center, Groupement Hospitalier Nord, Université Lyon 1, France

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Philippe Neyret Albert Trillat Center, Groupement Hospitalier Nord, Université Lyon 1, France

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. They noted a significant correlation between good clinical results and good alignment. In four of their five failures, the tibial component was positioned in varus. Denham and Bishop, in a 1978 study of biomechanics in relation to knee reconstruction

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Zsombor Panti Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Mihai Nica Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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reconstruction using bone grafts or endoprostheses, the limiting factor for favourable and sustainable results was local tumour recurrence. Everything changed when chemotherapy (neoadjuvant or adjuvant) and radiation therapy were instituted in the treatment

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Francisco Figueroa Clinica Alemana-Universidad del Desarrollo, Santiago, Chile
Hospital Sotero del Rio, Santiago, Chile

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David Figueroa Clinica Alemana-Universidad del Desarrollo, Santiago, Chile

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Sven Putnis Southmead Hospital, Bristol, UK

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Rodrigo Guiloff Clinica Alemana-Universidad del Desarrollo, Santiago, Chile
Hospital Sotero del Rio, Santiago, Chile

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Patricio Caro Clinica Alemana-Universidad del Desarrollo, Santiago, Chile

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João Espregueira-Mendes Clínica do Dragão, Espregueira-Mendes Sports Centre – FIFA Medical Centre of Excellence, Portugal
Orthopaedics Department of Minho University, Portugal

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the anatomy and biomechanics, coupled with poor patient outcomes with non-operative management, resulted in the PLC often being labelled as the ‘dark side’ of the knee. 5 In the last two decades, extensive research 6 – 9 has resulted in a

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Hee-Nee Pang Department of Orthopaedic Surgery, Singapore General Hospital, Singapore and Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Hamid Rahmatullah Bin Abd Razak Department of Orthopaedic Surgery, Singapore General Hospital, Singapore

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Stephen Petis Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Douglas D. R. Naudie Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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Steven J. MacDonald Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ontario, Canada

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a rise in the incidence of revision TKA. In the current literature, the most common reasons for revision TKA are aseptic loosening, usually as a result of wear, and infection. 2 , 5 - 8 These, together with instability and stiffness, account for

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James R. Berstock Musculoskeletal Research Unit, University of Bristol, UK

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James R. Murray Avon Orthopaedic Centre, Southmead Hospital, Bristol, UK

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Michael R. Whitehouse Musculoskeletal Research Unit, University of Bristol, UK

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Ashley W. Blom Musculoskeletal Research Unit, University of Bristol, UK

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Andrew D. Beswick Musculoskeletal Research Unit, University of Bristol, UK

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-operative pain resulting in shorter hospital stays. 8 The subvastus approach was used in 1% of TKRs in England and Wales between 2004 and 2014. 1 Randomized controlled trials (RCTs) comparing these two approaches include small numbers of participants

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George C. Babis 2nd Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Konstantopouleio Hospital, Greece

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Vasileios S. Nikolaou 2nd Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Konstantopouleio Hospital, Greece

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irreversibly compromising the abductor mechanism. Apart from the posterolateral approach, other authors have published good results using direct lateral with or without osteotomy approaches 21 and more recently using the direct anterior approach. 22 , 23

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Chengxin Xie Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Wenjun Pan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Shouli Wang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xueli Yan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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assess outcomes, with a P -value less than 0.05 indicating a statistically significant difference. Sensitivity analyses We performed a sensitivity analysis on a case-by-case exclusion basis. Results After identifying total of 279

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T Gosens Department of Orthopedic and Trauma Surgery, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands
Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands

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B L den Oudsten Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands
Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands

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well-being. The important role of managing or adapting to the situation of lowered FS is also illustrated by the fact that not being able to manage or adapt to situations, in general, results in lower QOL, also in absence of disease ( 3 ). At the same

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Xuelei Zhang Department of Ultrasound, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Chengxin Xie Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Department of Endocrinology, Ministry of Education, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China
Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Luxia Wu Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Guoping Cai Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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topical TXA (tTXA) than intravenous TXA, and the advantages of tTXA have been demonstrated in other types of surgery such as hip replacement, knee replacement, and thoracic surgery ( 10 , 11 , 12 ). Studies have produced inconsistent results on whether

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Benedikt Johannes Braun Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Jörg Holstein Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Tobias Fritz Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Nils Thomas Veith Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Steven Herath Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Philipp Mörsdorf Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Tim Pohlemann Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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cent, 21 with possibly a higher number of undetected cases. A high level of suspicion is required for patients where the resulting injuries are inconsistent with trauma history and signs of neglect are seen. Injury patterns A knowledge of

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