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Tristan Ferry Service de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)

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Jolien Onsea Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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Tiphaine Roussel-Gaillard Institut des Agents Infectieux, Centre de Biologie et de Pathologie du Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Cécile Batailler Service de Chirurgie Orthopédique et de Médecine du Sport, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Thomas Fintan Moriarty AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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). Although the biofilm is a well-known problem in MSIs, the increasing incidence of antimicrobial resistance (AMR) is potentially even more worrisome. The most frequently isolated pathogen in MSI is Staphylococcus aureus (30–42%) ( 8 ). Despite a decrease

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Gerhard M. Hobusch Medical University of Vienna, Department of Orthopaedics and Trauma Surgery, Vienna, Austria

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Kevin Döring Medical University of Vienna, Department of Orthopaedics and Trauma Surgery, Vienna, Austria

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Rickard Brånemark Gothenburg University, Gothenburg, Sweden
Biomechatronics Group, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

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Reinhard Windhager Medical University of Vienna, Department of Orthopaedics and Trauma Surgery, Vienna, Austria

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, 2 63% of amputees suffer from one or more skin problems that lead to daily routine activity limitations in one third of these patients. 3 Around 70% of amputees develop phantom limb pain (PLP) or residual limb pain (RLP), 4 14.5% of

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Hanna Wellauer Department of Orthopaedic Surgery and Traumatology, HFR Fribourg Hospital, University of Fribourg, Fribourg, Switzerland
Division of Orthopaedics and Trauma Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland

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Roman Heuberger RMS Foundation, Bettlach, Switzerland

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Emanuel Gautier Department of Orthopaedic Surgery and Traumatology, HFR Fribourg Hospital, University of Fribourg, Fribourg, Switzerland

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Moritz Tannast Department of Orthopaedic Surgery and Traumatology, HFR Fribourg Hospital, University of Fribourg, Fribourg, Switzerland

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Hubert Steinke Institute for the History of Medicine, University of Bern, Bern, Switzerland

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Peter Wahl Division of Orthopaedics and Trauma Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland
Faculty of Medicine, University of Berne, Berne, Switzerland

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tip ( 101 , 102 , 104 ). The long-term results of the Lord and AML stems and the problems encountered at revision led to the creation of the TriLock stem, introduced in 1981 ( 105 ). The porous coating was limited to the proximal area, in order to

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Giuseppe Solarino Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Giovanni Vicenti Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Massimiliano Carrozzo Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Guglielmo Ottaviani Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Biagio Moretti Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Luigi Zagra IRCCS Istituto Ortopedico Galeazzi, Hip Department, Milan, Italy

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  • Modular neck (MN) implants can restore the anatomy, especially in deformed hips such as sequelae of development dysplasia.

  • Early designs for MN implants had problems with neck fractures and adverse local tissue, so their use was restricted to limited indications.

  • Results of the latest generation of MN prostheses seem to demonstrate that these problems have been at least mitigated.

  • Given the results of the studies presented in this review, surgeons might consider MN total hip arthroplasty (THA) for a narrower patient selection when a complex reconstruction is required.

  • Long MN THA should be avoided in case of body mass index > 30, and should be used with extreme caution in association with high offset femoral necks with long or extra-long heads. Cr-Co necks should be abandoned, in favour of a titanium alloy connection.

  • Restoring the correct anatomic femoral offset remains a challenge in THA surgeries.

  • MN implants have been introduced to try to solve this problem. The MN design allows surgeons to choose the appropriate degree and length of the neck for desired stability and range of motion.

Cite this article: EFORT Open Rev 2021;6:751-758. DOI: 10.1302/2058-5241.6.200064

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Enrique Gómez-Barrena Department of Orthopaedic Surgery and Traumatology, Hospital La Paz-IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain

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Christian Ehrnthaller Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Germany

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  • Long bone non-unions represent a serious clinical and socioeconomical problem due to the prolonged episodes, frequent sequelae, and variable treatment effectiveness.

  • Bone grafts, classically involving the autologous iliac crest graft as the ‘gold standard’ bone graft, enhance bone regeneration and fracture healing incorporating osteoconductive and/or osteoinductive/osteogenic capacity to the non-union under treatment.

  • Structural alternatives to autologous bone grafts include allografts and bone substitutes, expanding the available stock but loosing biological properties associated with cells in the graft.

  • Biological alternatives to autologous bone grafts include bone marrow concentration from iliac crest aspiration, bone marrow aspiration from reaming of the diaphyseal medullary canal in the long bones, and isolated, expanded mesenchymal stem cells under investigation.

  • When the combination with natural and synthetic bone substitutes allows for larger volumes of structural grafts, the enhancement of the biological regenerative properties through the incorporation of cells and their secretoma permits to foresee new bone grafting solutions and techniques.

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Francisco Figueroa Knee Unit, Hospital Dr Sotero del Rio, Chile; Knee Unit, Clinica Alemana-Universidad del Desarrollo, Chile

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David Figueroa Knee Unit, Clinica Alemana-Universidad del Desarrollo, Chile

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João Espregueira-Mendes Clínica do Dragão, Espregueira-Mendes Sports Centre - FIFA Medical Centre of Excellence, Portugal; Dom Henrique Research Centre, Portugal; 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics, University of Minho, Portugal; ICVS/3B’s–PT Government Associate Laboratory, Portugal; Orthopaedics Department of Minho University, Portugal

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  • Graft size in hamstring autograft anterior cruciate ligament (ACL) surgery is an important factor directly related to failure. Most of the evidence in the field suggests that the size of the graft in hamstring autograft ACL reconstruction matters when the surgeon is trying to avoid failures.

  • The exact graft diameter needed to avoid failures is not absolutely clear and could depend on other factors, but newer studies suggest than even increases of 0.5 mm up to a graft size of 10 mm are beneficial for the patient. There is still no evidence to recommend the use of grafts > 10 mm.

  • Several methods – e.g. folding the graft in more strands – that are simple and reproducible have been published lately to address the problem of having an insufficient graft size when performing an ACL reconstruction. Due to the evidence presented, we think it is necessary for the surgeon to have them in his or her arsenal before performing an ACL reconstruction.

  • There are obviously other factors that should be considered, especially age. Therefore, a larger graft size should not be taken as the only goal in ACL reconstruction.

Cite this article: EFORT Open Rev 2018;3:93-97. DOI: 10.1302/2058-5241.3.170038

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Mario Herrera-Pérez Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain
School of Medicine, Universidad de La Laguna, Tenerife, Spain

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Pablo Martín-Vélez Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain

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David González-Martín Foot and Ankle Unit, Orthopaedic Department, Hospital Universitario de Canarias, Tenerife, Spain
School of Medicine, Universidad de La Laguna, Tenerife, Spain

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Miguel Domínguez-Meléndez Foot and Ankle Unit, Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain

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Ahmed E Galhoum Specialty Doctor Trauma and Orthopaedics, George Eliot Hospital NHS Trust, Nuneaton, UK

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Victor Valderrabano Schmerzklinik, Basel, Switzerland
University of Basel, Basel, Switzerland

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Sergio Tejero Foot and Ankle Unit, Hospital Universitario Virgen del Rocío, Sevilla, Spain
School of Medicine, Universidad de Sevilla, Sevilla, Spain

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  • Osteoporotic ankle fractures result from mechanical forces that would not ordinarily result in fracture, known as ‘low-energy’ trauma, such as those equivalent to a fall from a standing height or less.

  • Osteoporotic ankle fractures in frail patients are becoming more and more frequent in daily practice and represent a therapeutic challenge for orthopaedic surgeons.

  • The main problems with frail patients are the poor condition of the soft tissues around the ankle, dependence for activities of daily living and high comorbidity.

  • The decision to operate on these patients is complex because conservative treatment is poorly tolerated in unstable fractures and conventional open reduction and internal fixation is associated with a high rate of complications.

  • The authors conducted a narrative review of the literature on primary tibiotalocalcaneal nailing of ankle fractures in frail patients and categorized the different factors to consider when treatment is indicated for this conditon. Difficulty of ambulation, age over 65 years old, deteriorated baseline state and instability of the fracture were the most frequently considered factors.

  • Finally, the authors propose an easy and quick clinical scoring system to help in the decision-making process, although further comparative studies are required to explore its validity.

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T Gosens Department of Orthopedic and Trauma Surgery, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands
Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands
Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands

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B L den Oudsten Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands
Center of Research on Psychological and Somatic disorders (CoRPS), Tilburg University, Tilburg, The Netherlands

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knee or hip problems, not being able to walk further than the corner of the street due to back problems, or not being able to hold a grandchild due to problems of the wrist or shoulder is not life-threatening, such as other (chronic) diseases (e

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Pierre Hoffmeyer University Hospitals of Geneva, Switzerland

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particle-producing implant that destroys the surrounding skeleton and soft tissues. Early identification of potential problems will save much unnecessary operative activity or the use of massive implants to fill large, avoidable, defects. Registry data can

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Philippe Massin Diderot University Paris, Faculty of Medicine, Paris, Île-de-France, France

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demanding and emotional relationship with his students whom, he freely admitted, he did not hesitate to bully, because he wanted to get the best out of them. This did not prevent him from worrying about a family or a personal problem after having reprimanded

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