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Martin McNally The Oxford Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Geertje Govaert Department of Trauma Surgery, University of Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands

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Maria Dudareva The Oxford Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Mario Morgenstern Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium

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chronic persistent infected non-union which may be very difficult to eradicate. 4 , 5 Considering the importance of diagnosing and treating an infected fracture, it is surprising that it is only very recently that an accepted definition of fracture

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Morten Schultz Larsen Department of Orthopaedics and Traumatology, Odense University Hospital, Denmark

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Hagen Schmal Department of Orthopaedics and Traumatology, Odense University Hospital, Denmark

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Koh et al 5 including 733 patients with 834 fractures showed an overall healing rate of 85% and a revision rate of 12.6%. Lim et al 49 tested 46 variables for association with healing time longer than six months or non-union. High BMI and

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Nikolaos Gougoulias Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Hesham Oshba Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Apostolos Dimitroulias Jacobi Medical Center – Trauma Unit – Bronx, New York, USA

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Anthony Sakellariou Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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Alexander Wee Frimley Health NHS Foundation Trust, Frimley Park Hospital, Frimley, UK

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approximately 15% in matched control groups of non-diabetic patients. 1 , 3 – 5 A recent large-scale study showed that diabetes mellitus (DM) had the highest odds for amputation after ankle fracture fixation, compared to any other risk factors, 6

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Mohsen Raza Department of Trauma & Orthopaedics, St George’s University Hospitals NHS Foundation Trust, London, UK

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Daniel Murphy Department of Trauma & Orthopaedics, St George’s University Hospitals NHS Foundation Trust, London, UK

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Yael Gelfer Department of Trauma & Orthopaedics, St George’s University Hospitals NHS Foundation Trust, London, UK
St George’s, University of London, London, UK

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Taiwan Case report / 4 4.0 1 Post-osteomyelitis deformity Pelvis, Femur ✓ Not stated ✓ – Clinical: gait/squat assessment – Radiographic union – Complications – Radiographic assessment: lateral centre edge (CE) angle, acetabular

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Victor Lu School of Clinical Medicine, University of Cambridge, Cambridge, UK

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Maria Tennyson Department of Trauma and Orthopaedics, Addenbrooke’s Hospital, Cambridge, UK

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Andrew Zhou School of Clinical Medicine, University of Cambridge, Cambridge, UK

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Ravi Patel Department of Trauma and Orthopaedics, Shrewsbury and Telford Hospital NHS Trust, UK

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Mary D Fortune Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK

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Azeem Thahir Department of Trauma and Orthopaedics, Addenbrooke’s Hospital, Cambridge, UK

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Matija Krkovic Department of Trauma and Orthopaedics, Addenbrooke’s Hospital, Cambridge, UK

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patients over 55 ( 6 ), open reduction internal fixation (ORIF) have not produced satisfactory outcomes in some studies. Litchfield reported a 22.6% non-union rate (7/31) ( 7 ), whilst Beauchamp et al. reported a total complication rate of 50.1% and an

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Frédéric Vauclair Department of Orthopaedics and Traumatology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

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Patrick Goetti Department of Orthopaedics and Traumatology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

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Ngoc Tram V. Nguyen Mayo Clinic, Rochester, Minnesota, USA

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Joaquin Sanchez-Sotelo Mayo Clinic, Rochester, Minnesota, USA

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MD . Advances in the management of humeral nonunion . J Am Acad Orthop Surg 2003 ; 11 : 48 – 59 . 10. Ackerman G Jupiter JB . Non-union of fractures of the distal end of the humerus . J Bone Joint Surg Am 1988

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Duy Nguyen Anh Tran The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Bao Tu Thai Nguyen The International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Tan Thanh Nguyen Department of Orthopedics, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam

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Yu-Pin Chen Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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Yi-Jie Kuo Department of Orthopedics, Taipei Municipal Wan-Fang Hospital, Taipei, Taiwan
Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

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negative impact on the bone-healing process ( 61 , 62 ). Recent meta-analyses have substantiated this concern, establishing smoking as a risk factor for delayed bone union and non-union ( 57 , 63 ). While these findings are well-supported, it is

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Elisa Pala Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Alberto Procura Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Giulia Trovarelli Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Antonio Berizzi Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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metastatic lesions or (ii) post-radiation fracture in patients previously treated for soft tissue sarcoma (1 case). We decided to also include the last patient in the study because post-radiation fracture has a high risk of non-union and needs a careful

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Marco Guidi Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland

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Florian S. Frueh Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland

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Inga Besmens Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland

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Maurizio Calcagni Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, Zurich, Switzerland

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strength in all patients was 93% of the contralateral hand. This study did not report any infections, non-union or rotational deformities. No cases of complex regional pain syndrome were reported. One patient underwent screw removal because of proximal

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Ashoklal Ramavath Department of Orthopaedic Surgery, Chapel Allerton Hospital, Leeds, UK

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Jonathan N. Lamb Department of Orthopaedic Surgery, Chapel Allerton Hospital, Leeds, UK
University of Leeds, Leeds, UK

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Jeya Palan Department of Orthopaedic Surgery, Chapel Allerton Hospital, Leeds, UK

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Hemant G. Pandit Department of Orthopaedic Surgery, Chapel Allerton Hospital, Leeds, UK
University of Leeds, Leeds, UK

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Sameer Jain Department of Orthopaedic Surgery, Chapel Allerton Hospital, Leeds, UK

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PTS stems. Goudie et al reported a union rate of 91% in a series of 79 patients treated with IF over a five-year period and found that non-anatomic reduction and infection were associated with nonunion. 67 Maggs et al reported a series of cement

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