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Tristan Ferry Service de Maladies Infectieuses et Tropicales, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France
Université Claude Bernard Lyon 1, Villeurbanne, France
Centre de Références des IOA Complexes de Lyon, CRIOAc Lyon, Lyon, France
StaPath team, Centre International de Recherche en Infectiologie, CIRI, Inserm U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France
Education and Clinical Officer of the ESCMID Study Group for Non-traditional Antibacterial Therapy (ESGNTA)

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Jolien Onsea Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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Tiphaine Roussel-Gaillard Institut des Agents Infectieux, Centre de Biologie et de Pathologie du Nord, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Cécile Batailler Service de Chirurgie Orthopédique et de Médecine du Sport, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France

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Thomas Fintan Moriarty AO Research Institute Davos, Clavadelerstrasse 8, Davos Platz, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
Department of Development and Regeneration, KU Leuven, Oude Markt 13, Leuven, Belgium

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, limited mobility, and a higher mortality rate compared to patients who do not develop this complication ( 3 , 6 ). Management concepts consist of a combined surgical and antibiotic treatment approach. Because these infections are biofilm

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Francesco Benazzo Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Stefano M.P. Rossi Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Alberto Combi Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Sanjay Meena SICOT Fellow at Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Matteo Ghiara Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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of articular degeneration. Planning Planning is of utmost importance when approaching this challenging surgery. Clinical and radiological evaluations must address a number of issues: diagnosis (to exclude latent infection), approach, axis, bone

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Maria Anna Smolle Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Joanna Szkandera Division of Clinical Oncology, Internal Medicine, Medical University of Graz, Graz, Austria

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Dimosthenis Andreou Division of Orthopaedic Oncology and Sarcoma Surgery, Helios Klinikum Bad Saarow, Sarcoma Center Berlin-Brandenburg, Berlin, Germany

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Emanuela Palmerini Chemotherapy Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna University, Bologna, Italy

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Marko Bergovec Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Andreas Leithner Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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variable treatment responses, however, therapeutic approaches for different subtypes may significantly differ. Therefore, the aim of the present systematic review was to summarize recent knowledge on treatment of patients with locally advanced

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Andrea Angelini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Nicolò Mosele Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Elisa Pagliarini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Diagnostic and treatment algorithm for Gorham–Stout disease. Radiotherapy and medical treatments play a very important role in the management of the disease, and many pharmacological approaches have been tried during the past years. Moderate doses

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Olga D. Savvidou First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Panagiotis Koutsouradis Department of Orthopaedic Surgery, 417 Veterans Hospital (NIMTS), Athens, Greece

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George D. Chloros First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Ioannis Papanastasiou First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Thomas Sarlikiotis First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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Aggelos Kaspiris Laboratory of Molecular Pharmacology/ Sector for Bone Research, School of Health Sciences, University of Patras, Patras, Greece

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Panayiotis J. Papagelopoulos First Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, ‘ATTIKON’ Hospital, Athens, Greece

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patients with a bone lesion is presented ( Fig. 1 ). 7 Fig. 1 Algorithm for patients presenting with a bony lesion around the elbow. A multidisciplinary team approach should include an orthopaedic oncologist, an interventional radiologist

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Deepak Samson The Centre for Nerve Injury and Paralysis, The Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, UK

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Chye Yew Ng The Upper Limb Unit, Wrightington Hospital, UK

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Dominic Power The Centre for Nerve Injury and Paralysis, The Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, UK

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although the reduced time to re-innervation provides good supportive evidence for this approach in the surgical management of nerve injuries at other sites, including the brachial plexus. 34 Results Although the early results of lower limb

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Mark Anthony Roussot University College London Hospitals NHS Foundation Trust, London, UK
Department of Orthopaedic Surgery, University of Cape Town, SA

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Fares Sami Haddad University College London Hospitals NHS Foundation Trust, London, UK

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of the early 1970s, considerable advances have been made in terms of component design, peri-operative care, alignment strategies, surgical approaches, and, more recently, the use of advanced technologies such as computer navigation and robotic

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Pieter Caekebeke Ziekenhuis Oost-Limburg, Department of Orthopaedics Surgery and Traumatology, Genk, Belgium

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Joris Duerinckx Ziekenhuis Oost-Limburg, Department of Orthopaedics Surgery and Traumatology, Genk, Belgium

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Roger van Riet AZ Monica, Department of Orthopedic Surgery, Antwerp, Belgium
University Hospital Antwerp, Department of Orthopedic Surgery, Edegem, Belgium

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higher when the surgical repair is performed at later stages. 37 Early surgical repair is therefore preferred. Approach Surgical repair of the DBT can be performed through a single or double-incision approach. Both approaches have been extensively

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Michael de Buys Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa

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Krisantha Moodley Emergency Department, ER Consulting, Johannesburg, South Africa

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Josip Nenad Cakic Department Orthopaedic Surgery, Life Fourways Hospital, Johannesburg, South Africa

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Jurek R T Pietrzak Orthopaedic Surgery, University of Witswatersrand, Johannesburg, South Africa

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rate approaching 40% ( 25 , 26 ). Colonization by S. aureus is a modifiable risk factor for SSI and carriers of S. aureus have a 9–10 times greater risk of developing SSI than non-carriers ( 27 , 28 ). MRSA colonization leads to four times greater

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Javier Masquijo Department of Pediatric Orthopaedics, Sanatorio Allende, Córdoba, Argentina

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Alpesh Kothari Department of Paediatric Orthopaedics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

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should be the primary approach for stable JOCD of the knee. Although there is a lack of evidence for specific non-operative treatments, most authors recommend at least three to six months before the decision for surgical treatment. Non-operative treatment

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