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Khaled M. Sarraf St Mary’s Hospital, Imperial College Healthcare Trust, London, UK

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Ravi Popat St Mary’s Hospital, Imperial College Healthcare Trust, London, UK

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Kathryn L. Kneale St Mary’s Hospital, Imperial College Healthcare Trust, London, UK

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Rajarshi Bhattacharya St Mary’s Hospital, Imperial College Healthcare Trust, London, UK

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Manoj Ramachandran The Royal London Hospital, Barts Health NHS Trust, London, UK

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Pramod Achan The Royal London Hospital, Barts Health NHS Trust, London, UK

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Sammy A. Hanna The Royal London Hospital, Barts Health NHS Trust, London, UK

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three studies ( n = 94) specified the bearing surfaces used. There were 28 metal-on-polyethylene, 23 ceramic-on-ceramic, nine ceramic-on-polyethylene and 35 metal-on-metal. The demographics of the patients in the studies are summarized in Table 1

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Ting-Yu Tu Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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Chun-Yu Chen Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan
Department of Occupational Therapy, Shu-Zen Junior College of Medicine and Management, Kaohsiung City, Taiwan
Department of Biomedical Engineering, I-Shou University, Kaohsiung City, Taiwan

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Pei-Chin Lin Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
Department of Pharmacy, School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan

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Chih-Yang Hsu Department of Internal Medicine, Division of Nephrology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

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Kai-Cheng Lin Department of Orthopedics, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan

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acetabular component, a network meta-analysis ( 57 ) with 77 included studies demonstrated that newer implant combinations, defined by bearing surface materials (metal-on-polyethylene, ceramic-on-polyethylene, ceramic-on-ceramic, or metal-on-metal), head size

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Shaho Hasan Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Peter van Schie Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, The Netherlands

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Bart L Kaptein Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Jan W Schoones Walaeus Library, Leiden University Medical Centre, Leiden, The Netherlands

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Perla J Marang-van de Mheen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Safety & Security Science, Delft University of Technology, Delft, The Netherlands

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Rob G H H Nelissen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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in serum or urine were excluded. Moreover, studies without aseptic loosening as an outcome as well as studies among patients with an infection, tumor reconstructions, or metal-on-metal implants were excluded. In addition, animal studies and in vitro

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Geert Meermans Bravis Hospital, Roosendaal, The Netherlands

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George Grammatopoulos The Ottawa Hospital, Ottawa, Ontario, Canada

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Moritz Innmann Heidelberg University Hospital, Heidelberg, Germany

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David Beverland Belfast Health and Social Care Trust, Belfast, UK

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orientation and position of the implanted cup. Improper acetabular orientation and position can lead to: (i) limited range of motion ( 1 ); (ii) increased dislocation rate ( 2 ); (iii) accelerated wear of polyethylene ( 3 ), metal-on-metal ( 4 ) and ceramic

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Eustathios Kenanidis Hôpital de la Tour, Geneva, Switzerland
Academic Orthopaedic Department, Papageorgiou General Hospital, Aristotle University Medical School, Thessaloniki, Greece
Centre of Orthopaedics and Regenerative Medicine (CORE) – Centre of Interdisciplinary Research and Innovation (CIRI) – Aristotle University Thessaloniki, Greece

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George Kyriakopoulos Hôpital de la Tour, Geneva, Switzerland
Gennimatas General Hospital, Cholargos, Athens, Greece

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Rajiv Kaila Hôpital de la Tour, Geneva, Switzerland

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Panayiotis Christofilopoulos Hôpital de la Tour, Geneva, Switzerland

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. J Arthroplasty 2014 ; 29 : 383 – 386 . 21. Berber R Khoo M Cook E et al. Muscle atrophy and metal-on-metal hip implants: a serial MRI study of 74 hips . Acta Orthop 2015 ; 86 : 351 – 357 . 22

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Claus Varnum The Danish Hip Arthroplasty Register
Department of Orthopaedic Surgery, Vejle Hospital, Vejle, Denmark

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Alma Bečić Pedersen Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark

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Per Hviid Gundtoft Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark

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Søren Overgaard The Danish Hip Arthroplasty Register
Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark
Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark

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with ceramic-on-ceramic and metal-on-polyethylene bearings . Acta Orthop 2015 ; 86 : 477 - 484 . 10. Smith AJ Dieppe P Vernon K Porter M Blom AW . Failure rates of stemmed metal-on-metal hip

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Philippe Hernigou Hôpital Henri Mondor, University of Paris-Est, France

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François Roubineau Hôpital Henri Mondor, University of Paris-Est, France

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Charlie Bouthors Hôpital Henri Mondor, University of Paris-Est, France

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Charles-Henri Flouzat-Lachaniette Hôpital Henri Mondor, University of Paris-Est, France

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CoC. But as previously (with a ceramic cup) this may necessitate removal of the stem to implant a new ceramic head on a new taper. A metal-on-metal bearing surface should be avoided because the ceramic is harder than metal and rapid three-body abrasive

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Rory Cuthbert The Royal London Hospital, London, UK

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James Wong Barking, Havering and Redbridge University Hospitals, Romford, UK

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Philip Mitchell South West London Elective Orthopaedic Centre, Epsom, UK

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Parag Kumar Jaiswal Royal Free London NHS Foundation Trust, London, UK

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– illustrated by a C-shaped bubble on plain radiographs. Critically, the resultant metal-on-metal articulation between the inner femoral head and the acetabular socket causes rapid wear, release of metal ions and local soft-tissue metallosis. Meanwhile the

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Giuseppe Solarino Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Giovanni Vicenti Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Massimiliano Carrozzo Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Guglielmo Ottaviani Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Biagio Moretti Department of Neuroscience and Organs of Sense, Orthopaedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy

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Luigi Zagra IRCCS Istituto Ortopedico Galeazzi, Hip Department, Milan, Italy

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particularly when modular neck stems were paired with metal-on-metal articulating bearing, which was reported to increase revision rates even further. 45 The authors conclude that it remains to be established whether this is the result of implant taper

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Andreas Fontalis Royal National Orthopaedic Hospital NHS Trust, Brockley Hill, Stanmore, UK
Academic Unit of Bone Metabolism, University of Sheffield Medical School, Sheffield, UK

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Eustathios Kenanidis Academic Orthopaedic Unit, Aristotle University Medical School, Papageorgiou General Hospital, Thessaloniki, Greece
Centre of Orthopaedic and Regenerative Medicine (CORE), Center for Interdisciplinary Research and Innovation (CIRI), Aristotle University of Thessaloniki, Thessaloniki, Greece

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Katharine Bennett-Brown Chelsea and Westminster Hospital NHS Foundation Trust, Chelsea, London, UK

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Eleftherios Tsiridis Academic Orthopaedic Unit, Aristotle University Medical School, Papageorgiou General Hospital, Thessaloniki, Greece
Centre of Orthopaedic and Regenerative Medicine (CORE), Center for Interdisciplinary Research and Innovation (CIRI), Aristotle University of Thessaloniki, Thessaloniki, Greece

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-B Yoon T-R . Total hip arthroplasty using large-diameter metal-on-metal articulation in patients with neuromuscular weakness . J Arthroplasty 2014 ; 29 : 797 – 801 . 34. Brown TS Tibbo ME Arsoy D et al

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