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Cheuk Yin Li School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Kenneth Jordan Ng Cheong Chung School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Omar M. E. Ali School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Nicholas D. H. Chung School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Cheuk Heng Li School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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increasingly ageing population. 3 The most common indication for TKR is osteoarthritis (OA). 1 In 2018, 96.2% of primary knee replacements were conducted solely due to osteoarthritis. 2 TKR helps to improve quality of life and function in end

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Andrea Pratobevera Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy

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Romain Seil Department of Orthopaedic Surgery, Centre Hospitalier Luxembourg-Clinique d’Eich, Luxembourg, Luxembourg
Luxembourg Institute of Research in Orthopaedics, Sports Medicine and Science (LIROMS), Luxembourg, Luxembourg
Department of Orthopaedic Surgery, Centre Hospitalier Luxembourg-Clinique d’Eich, Luxembourg, Luxembourg

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Jacques Menetrey Centre de Medecine du Sport et de l’Exercice - Swiss Olympic Medical Center, Hirslanden Clinique La Colline, Geneva, Switzerland
Orthopaedic Surgery Service, University Hospital of Geneva, Geneva, Switzerland

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functional demands ( 2 , 3 , 4 ). Osteotomies around the knee redistribute the load to the compartment which is unaffected by osteoarthritis, aiming to alleviate symptoms and delay or avoid the need for later arthroplasty. Historically, osteotomies were

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Salvi Prat-Fabregat Hospital Clinic of Barcelona, Spain

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Pilar Camacho-Carrasco Hospital Clinic of Barcelona, Spain

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that, in some specific patients, TKA could be the primary procedure. Age > 65 years, local osteopaenia, corticoid use and pre-existing osteoarthritis are identified as the main reasons indicating a primary arthroplasty. What outcomes can be

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Nuno Marques Luís Knee and Ankle Surgery, Arthroscopy and Sports Trauma Unit; Orthopedic Center, Hospital Cuf Descobertas, Lisbon, Portugal

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Ricardo Varatojo Knee and Ankle Surgery, Arthroscopy and Sports Trauma Unit; Orthopedic Center, Hospital Cuf Descobertas, Lisbon, Portugal

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the anatomic tibiofemoral angle does not reproduce a correct estimation of the mechanical tibiofemoral angle. The anatomic tibiofemoral angle is valgus with an offset of 4–6° for healthy individuals. In patients with knee osteoarthritis, the anatomic

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Joost van Tilburg Department of Orthopedics, Herlev Gentofte Hospital, Hellerup, Copenhagen, Denmark

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Mikkel Rathsach Andersen Department of Orthopedics, Herlev Gentofte Hospital, Hellerup, Copenhagen, Denmark

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osteoarthritis (OA) and is known to disproportionally increase and accelerate knee arthrosis ( 4 , 5 , 6 , 7 ). Aging as well is correlated with OA ( 8 , 9 , 10 ), and since the world’s population is getting older, this further increases the demand for

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Aline Van Oevelen Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium
Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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Arne Burssens Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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Nicola Krähenbühl Department of Orthopaedics, University Hospital Basel, Basel, Switzerland

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Alexej Barg Department of Orthopaedics and Trauma, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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Bernhard Devos Bevernage Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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Emmanuel Audenaert Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium
Department of Electromechanics, InViLab research group, University of Antwerp, Antwerp, Belgium
Department of Trauma and Orthopedics, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Beat Hintermann Department of Orthopaedics, Kantonsspital Baselland, Liestal, Switzerland

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Jan Victor Department of Orthopaedics, University Hospital of Ghent, Ghent, Belgium

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, osteoarthritis; RCS, retrospective cohort study. Table 2 Study details of clinical and radiographical outcomes, correlations and conclusions. Study Biomechanical outcome Clinical outcome Conclusion Subjective measures

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Francesco Benazzo Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Stefano M.P. Rossi Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Alberto Combi Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Sanjay Meena SICOT Fellow at Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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Matteo Ghiara Department of Clinical-Surgical Sciences, Diagnostics and Pediatrics, University of Pavia, Italy

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cartilage damage; insufficient reduction induces limb malalignment. These three consequences of trauma lead to the development of osteoarthritis. 7 Following a tibial plateau fracture, the incidence of arthritis is higher 8 , 9 than with distal

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Michele Vasso Concordia Hospital for Special Surgery, Rome, Italy

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Alexander Antoniadis Bürgerspital Solothurn, Switzerland

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Naeder Helmy Bürgerspital Solothurn, Switzerland

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literature to elucidate the correct clinical indications and the precise radiological criteria, and the main causes of UKA failure. Indications for UKA Current indications for UKA implantation are: unicondylar osteoarthritis (OA) or osteonecrosis

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Jason Trieu University of Melbourne Department of Surgery, Fitzroy, Australia

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Chris Schilling University of Melbourne Department of Surgery, Fitzroy, Australia

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Michelle M. Dowsey University of Melbourne Department of Surgery, Fitzroy, Australia
Department of Orthopaedic Surgery, St Vincent’s Hospital, Fitzroy, Australia

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Peter F. Choong University of Melbourne Department of Surgery, Fitzroy, Australia
Department of Orthopaedic Surgery, St Vincent’s Hospital, Fitzroy, Australia

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Introduction The growing burden of knee osteoarthritis presents a significant challenge facing many communities. 1 Total knee replacement (TKR) remains the only definitive treatment option available for advanced arthritis, and this has

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Sohail Nisar Leeds Institute of Rheumatic and Musculoskeletal Medicine, UK
Academic Department of Trauma and Orthopaedics, LGI, University of Leeds, Leeds, UK
Leeds Teaching Hospitals Trust, UK

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Jeya Palan Leeds Teaching Hospitals Trust, UK

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Charles Rivière MSK Lab - Imperial College London, White City Campus, London, UK
The Lister Hospital, Chelsea Bridge, London, UK
Centre de l’Arthrose - Clinique du Sport, Bordeaux-Mérignac, France

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Mark Emerton Leeds Teaching Hospitals Trust, UK

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Hemant Pandit Leeds Institute of Rheumatic and Musculoskeletal Medicine, UK
Leeds Teaching Hospitals Trust, UK

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Introduction Over 100,000 total knee replacements (TKR) are performed annually for painful end-stage osteoarthritis (OA) in the UK. 1 The main reason for undertaking a TKR is to provide pain relief as well as improving function and

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