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multiple vertebral lytic lesions ( 15 ). Molecular characteristics Etiopathogenetic mechanisms in GSD are still unclear and uncertain, nevertheless, several hypotheses have been made since the Gorham and Stout article of 1955 ( 2 ). There are three
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-osseous arteries are end-arteries and septic emboli may become entrapped, resulting in extensive destruction, leading to wedging or collapse of the body. 41 Infection extending to the adjacent disc and vertebra creates the typical lesions of spondylodiscitis
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pes cavus, such as pes cavovarus (PCV) or pes calcaneocavus, may be related to a neurological lesion and its secondary muscle imbalance and be symptomatic. The differentiation between the various forms of pes cavus is paramount to understand its
School of Medicine, University of Belgrade, Serbia
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School of Medicine, University of Belgrade, Serbia
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useful in detecting the location of an injury, co-existing pathologies and neurological diseases when a nerve lesion is suspected. 42 , 43 Treatment Treatment of radial nerve palsy can be either non-operative or operative. Non
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neurological disorder. Thus, neurological disorders must be looked for in the family history and clinical and electrophysiologica evaluation of the patient is necessary to eliminate any very subtle neurological lesion. Patho-anatomy There are several
Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
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Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
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contrast to vital capacity and lung volumes improving ( 67 ). The procedure presents with high rate of neurological complications of 7% with brachial plexus palsy being the most common ( 68 ). Rib and lamina fractures, infection and lesions are also
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain
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feet of athletes are not unusual problems. 6 Often, the aforementioned problems are neglected as the more noticeable musculoskeletal lesion draws the orthopaedic surgeon’s attention. Commonly, with conservative management, including a sporadic
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displaced fractures. It has been reported that vascular compromise exists in up to 10% to 20% of displaced fractures. 2 , 11 , 12 It is mandatory to check the distal pulse and hand perfusion pre-operatively and post-operatively. Neurological
Department of Surgery, Universidad de La Laguna, Tenerife, Spain
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University of Basel, Basel, Switzerland
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Department of Orthopedic and Rehabilitation, University of Iowa, Iowa, USA
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Department of Surgery, Universidad de La Laguna, Tenerife, Spain
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Department of Surgery, Universidad de Sevilla, Sevilla, Spain
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chronic lateral instability. Another point of controversy is the relation between osteochondral lesions of the talus and the development of ankle OA. Weigelt et al. ( 10 ) reported in a 14-year-old follow-up study that osteochondral lesions of
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underlining the ineffectiveness of denosumab on the tumourous stromal cells ( 1 ). Following the successful use of denosumab in the treatment of osteoporosis and metastatic bone lesions ( 2 , 3 ), it has been approved by FDA in 2013 and later on by the
