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Logan Petit Department of Orthopedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut, USA

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Theodore Zaki Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA

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Walter Hsiang Department of Orthopedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut, USA

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Michael P. Leslie Department of Orthopedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut, USA

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Daniel H. Wiznia Department of Orthopedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut, USA

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Motorcycle thumb Collision Pelvic ring Fuel tank injuries Collision Lower extremity: femur, tibia, fibula Limb entrapment Lowside Lower extremity: heel Tyre-spoke injury Lowside Lower extremity: foot Crash modifying

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Michalis Panteli Academic Department of Trauma & Orthopaedics, Leeds General Infirmary; School of Medicine, University of Leeds, UK

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Peter V. Giannoudis Academic Department of Trauma & Orthopaedics, Leeds General Infirmary; School of Medicine, University of Leeds, UK

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will require limb amputation. 2 Antibiotic treatment Initial empiric antibiotic treatment should be commenced as soon as the culture samples have been obtained. The antibiotic regimen should then be tailored to the results of the cultures and

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Chengxiang Li Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
University of Basel, Basel, Switzerland

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Fatime Krasniqi Department of Oncology, University Hospital Basel, Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland

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Ricardo Donners The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Department of Radiology, University Hospital Basel, Basel, Switzerland

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Christoph Kettelhack The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland

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Andreas H Krieg Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland

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limited role and multimodal treatment that entails surgery, radiotherapy, and systemic chemotherapy may be indicated ( 60 , 61 ). In addition, although limb-preserving surgery to preserve limb function is the main trend in surgical protocols, amputation

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Joseph Genevière Faculty of Medicine, University of Geneva, Geneva, Switzerland
Co-first authors and equal contributors

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Shawna McCallin Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors

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Angela Huttner Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

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Truong-Thanh Pham Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Domizio Suva Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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options and amputation is not uncommon. 10 Bacteriophage therapy, also known as phage therapy (PT), has brought fresh hope in curing these patients. Phages are viruses that specifically infect bacteria. 11 They have an entirely different mechanism of

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Michael Beverly Botnar Research Centre, Nuffield Orthopaedic Centre, University of Oxford, Oxford

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David W Murray Botnar Research Centre, Nuffield Orthopaedic Centre, University of Oxford, Oxford

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compartment pressure initially with a proximal venous pressure cuff in position (Pv) followed by elevating the limb to empty the veins, then measuring the compartment pressure with a proximal arterial cuff in position (Pa). Subtracting the difference (Pv − Pa

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Gilles Pasquier Service de Chirurgie Orthopedique, Centre-Hospitalo-Universitaire de Lille, France

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Matthieu Ehlinger Service de Chirurgie Orthopedique et de Traumatologie, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, France

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Didier Mainard Service de Chirurgie Orthopédique, Cente Hospitalo-Universitaire de Nancy, Centre Hospitalo-Universitaire de Nancy, France

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focus on their indications. Should hinged implants be used only for lower-limb salvage surgery or should they be a regular choice for TKA revision surgery? Are their outcomes improving, or do they remain unsatisfactory? Implant constraints and the

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, “La Paz” University Hospital-IdiPaz, Madrid, Spain

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20, 21 Endo-Model rotating hinge prosthesis 22–36 Hinged Limb Preservation System (LPS) model 37 Custom-made rotating hinge model 38–41 NexGen rotating hinge knee model 42, 43 EnduRo model 44, 45 The

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Stefan Rammelt University Center of Orthopaedics & Traumatology, University Hospital Carl Gustav Carus, Dresden, Germany

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overall soft tissue condition and the neurovascular status of the injured limb ( Fig. 1 ). Fig. 1 Fracture-dislocation with impeding skin necrosis produced by a prominent medial fragment of the distal tibia. Immediate reduction is warranted

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Bülent Atilla Hacettepe University Faculty of Medicine, Department of Orthopaedics and Traumatology, Ankara, Turkey

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Hande Güney-Deniz Hacettepe University Faculty of Physical Therapy and Rehabilitation, Ankara, Turkey

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has shrunk. 23 Surgical excisions, including limb amputations, may be necessary for large pseudotumours, particularly if they erode long bones. Large abdominal pseudotumours present a special challenge in surgical management of haemophilia

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E Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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Alberto D Delgado-Martínez Department of Orthopaedic Surgery, Hospital Universitario de Jaén, Jaén, Spain
Department of Surgery, University of Jaén, Jaén, Spain

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Javier De Andrés-Ares Department of Anesthetics, Pain Unit, La Paz University Hospital, Madrid, Spain

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, 16 , 17 , 18 , 19 , 20 , 21 , 22 ). The purpose of this article is to conduct a narrative review of recent literature on the role of RF in treating pain in various orthopaedic conditions in upper and lower limbs, shoulder, elbow, hip, knee and

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