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Peter Richard Almeida University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa

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Lipalo Mokete University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa

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Nkhodiseni Sikhauli University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa

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Ahmad Mota University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa

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Bayanda Ndindwa University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa

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Jurek R T Pietrzak University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa

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, 11 , 12 ). Johnson et al. ( 13 ) reviewed 84 315 patients and found that malnutrition was the strongest risk factor for poor post-operative outcomes in TJA. Multiple publications highlight that malnutrition results in numerous post

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Jacobien H.F. Oosterhoff Department of Orthopaedic Surgery, Amsterdam UMC, University of Amsterdam, the Netherlands
Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Job N. Doornberg Department of Orthopaedic Surgery, Amsterdam UMC, University of Amsterdam, the Netherlands
Department of Orthopaedic & Trauma Surgery, Flinders Medical Centre, Flinders University, Adelaide, SA, Australia

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Machine Learning Consortium Members of the Machine Learning Consortium: Paul Algra, Michel van den Bekerom, Mohit Bhandari, Michiel Bongers, Charles Court-Brown, Anne-Eva Bulstra, Geert Buijze, Sofia Bzovsky, Neil Chen, Job Doornberg, Andrew Duckworth, J. Carel Goslings, Benjamin Gravesteijn, Olivier Groot, Gordon Guyatt, Laurent Hendrickx, Dirk-Jan Hofstee, Frank IJpma, Ruurd Jaarsma, Stein Janssen, Paul Jutte, Aditya Karhade, Lucien Keijser, Gino Kerkhoffs, David Langerhuizen, Jonathan Lans, Wouter Mallee, Matthew Moran, Margaret McQueen, Marjolein Mulders, Miryam Obdeijn, Tarandeep Oberai, Jacobien H.F. Oosterhoff, Rudolf Poolman, David Ring, Paul Tornetta III, Joseph Schwab, Emil H. Schemitsch, Niels Schep, Inger Schipper, Bram Schoolmeesters, Marc Swiontkowski, David Sanders, Sheila Sprague, Ewout Steyerberg, Stephen D. Walter, Monique Walenkamp

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orthopaedics has the potential to neutralize the influence of biased surgeons and thus overcome treatment inconsistencies, 16 , 50 thereby improving patients’ functional outcomes and reducing associated healthcare costs ( Fig. 3 ). Thus, small significant

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John-Henry Rhind Robert Jones Agnes Hunt Hospital, Oswestry, Shropshire, UK

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Eamon Ramhamadany Robert Jones Agnes Hunt Hospital, Oswestry, Shropshire, UK

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Ruaraidh Collins Basingstoke and North Hampshire Hospital, Basingstoke, Hampshire, UK

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Siddharth Govilkar Robert Jones Agnes Hunt Hospital, Oswestry, Shropshire, UK

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Debashis Dass Robert Jones Agnes Hunt Hospital, Oswestry, Shropshire, UK

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Stuart Hay Robert Jones Agnes Hunt Hospital, Oswestry, Shropshire, UK

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? Injury 2015 ; 46 : 1664 – 1668 . 40. Gamble D Jenkins PJ Edge MJ et al. Satisfaction and functional outcome with ‘self-care’ for the management of fifth metacarpal fractures . Hand (N Y) 2015 ; 10 : 607 – 612

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Thomas Collins Trauma & Orthopaedics, Wythenshawe Hospital, Wythenshawe, UK

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Dinesh Alexander Trauma & Orthopaedics, Salford Royal Hospital, Salford, UK

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Bilal Barkatali Trauma & Orthopaedics, Salford Royal Hospital, Salford, UK

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. Significantly improved in 7 of the 9 RCTs included. Trend towards improved outcomes in younger patients/early OA changes with PRP. Chang et al Improved functional outcomes with PRP up to a year post treatment. Less severe OA showed more benefit from PRP

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain

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should be informed to ensure that their expectations and functional goals are realistic and can be accomplished. The planning phase should ensure that surgery proceeds without complication, but the surgical team should be ready to handle unanticipated

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T. Fintan Moriarty AO Research Institute Davos, Switzerland

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Richard Kuehl University Hospital of Basel, Switzerland

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Tom Coenye Ghent University, Belgium

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Willem-Jan Metsemakers University Hospitals Leuven, Belgium

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Mario Morgenstern Trauma Centre, Murnau, Germany

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Edward M. Schwarz University of Rochester Medical Center, New York, USA

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Martijn Riool AMC, University of Amsterdam, The Netherlands

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Sebastian A.J. Zaat AMC, University of Amsterdam, The Netherlands

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Nina Khana University Hospital of Basel, Switzerland

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Stephen L. Kates Virginia Commonwealth University, Virginia, USA

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R. Geoff Richards AO Research Institute Davos, Switzerland

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ODRI is effective in all cases, and can lead to infections that negatively impact clinical outcome and significantly increase healthcare expenditure. 2 Pre-operative and correctly-timed prophylactic antibiotic intervention is mandatory for a

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Martin McNally The Oxford Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Geertje Govaert Department of Trauma Surgery, University of Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands

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Maria Dudareva The Oxford Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, UK

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Mario Morgenstern Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Switzerland

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Willem-Jan Metsemakers Department of Trauma Surgery, University Hospitals Leuven, Leuven, Belgium

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Introduction Successful treatment of a fracture is aimed at promoting bone healing and good functional recovery with the avoidance of complications which may impair function or prolong treatment. When an infection occurs, this can be a

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Shaho Hasan Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Peter van Schie Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, The Netherlands

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Bart L Kaptein Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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Jan W Schoones Walaeus Library, Leiden University Medical Centre, Leiden, The Netherlands

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Perla J Marang-van de Mheen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands
Department of Safety & Security Science, Delft University of Technology, Delft, The Netherlands

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Rob G H H Nelissen Department of Orthopaedics, Leiden University Medical Centre, Leiden, The Netherlands

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. The course of radiographic loosening, pain and functional outcome around the first revision of a total hip arthroplasty . BMC Musculoskeletal Disorders 2013 14 167 . ( https://doi.org/10.1186/1471-2474-14-167 ) 25 Yao JJ Maradit Kremers H Abdel

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Hamid Rahmatullah Bin Abd Razak Department of Bioengineering, Imperial College London, London, UK
Sengkang General Hospital, Singapore
Joint first authors

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Daniel Chew Faculty of Medicine, Imperial College London, London, UK
Joint first authors

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Zepur Kazezian Department of Bioengineering, Imperial College London, London, UK

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Anthony M.J. Bull Department of Bioengineering, Imperial College London, London, UK

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therapy that may improve pain parameters and functionality for mild to moderate knee OA, despite the limited evidence. 10 Today, nSTRIDE ® (Biomet Biologics, Warsaw, IN, USA) is the only available APS for clinical use in patients with early to

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Søren Overgaard Department of Orthopaedic Surgery and Traumatology, Copenhagen University Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Thomas M Grupp Aesculap AG Research & Development & Medical Scientific Affairs, Tuttlingen, Germany
Department of Orthopaedic and Trauma Surgery, Ludwig Maximilians University Munich, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Munich, Germany

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Rob GHH Nelissen Department of Orthopaedics, Leiden University Medical Center, Leiden, the Netherlands
Technical University Delft, Delft, the Netherlands

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Luca Cristofolini Department of Industrial Engineering, School of Engineering and Architecture, Alma Mater Studiorum - Università di Bologna, Bologna, Italy

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Anne Lübbeke Division of Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK

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Marcus Jäger Department of Orthopaedics, Trauma & Reconstructive Surgery St. Marien Hospital Mülheim an der Ruhr & Chair of Orthopaedics and Trauma Surgery University of Duisburg–Essen, Essen, Germany

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Matthias Fink TÜV Süd Product Service GmbH, Clinical Centre of Excellence, Munich Germany

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Sabine Rusch Aesculap AG Research & Development & Medical Scientific Affairs, Tuttlingen, Germany

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Hassan Achakri Zimmer Biomet, Clinical, Regulatory & Quality Affairs, Winterthur, Switzerland

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Francesco Benazzo IUSS Pavia, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy

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Dario Bergadano Medacta International SA, Medical Affairs, Castel San Pietro, Switzerland

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Georg N Duda Julius Wolff Institute and Center for Muskuloskeletal Surgery, Berlin Institute of Health at Charité Universitätsmedizin Berlin, Germany

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Christian Kaddick EndoLab Mechanical Engineering GmbH, Riedering, Germany

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Volkmar Jansson Department of Orthopaedic and Trauma Surgery, Ludwig Maximilians University Munich, Musculoskeletal University Center Munich (MUM), Campus Grosshadern, Munich, Germany

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Klaus-Peter Günther University Clinic Carl Gustav Carus, Center for Orthopaedic & Trauma Surgery, Technical University Dresden, Dresden, Germany

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ideal reference implant would be supported by survival analysis over a suitable period of time, patient-reported outcome measuresa (PROMs) data from registry and/or peer-reviewed published studies, functional outcome data, clinical and other complaint

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