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Daan Vermeulen Department of Orthopaedic Surgery, St. Antonius Hospital, Nieuwegein, Utrecht, The Netherlands

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Mara Rosa van der Valk Department of Orthopaedic Surgery, St. Antonius Hospital, Nieuwegein, Utrecht, The Netherlands

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Laurens Kaas Department of Orthopaedic Surgery, St. Antonius Hospital, Nieuwegein, Utrecht, The Netherlands

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formation of adhesions in and around the joint. 10 , 12 , 16 Furthermore, it is well known that lengthened immobilization has a detrimental effect on cartilage quality and thickness. In a study with paraplegics, it was discovered that the cartilage

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Cheuk Yin Li School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Kenneth Jordan Ng Cheong Chung School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Omar M. E. Ali School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Nicholas D. H. Chung School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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Cheuk Heng Li School of Medical Education, Newcastle University, Framlington Place, Newcastle upon Tyne, UK

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and adhesions which contributes to pain and restrictive joint motion. 14 Of TKR patients, 3–10% develop arthrofibrosis after TKR and report pain with activities from < 30% for light manual work to 78% for jumping and pivoting. 15 – 18

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Tim Kraal Department of Orthopaedic Surgery, Amphia Hospital, The Netherlands

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Lijkele Beimers Department of Orthopaedic Surgery, Slotervaart Center of Orthopedic Research & Education (SCORE), The Netherlands

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Bertram The Department of Orthopaedic Surgery, OLVG Hospital, The Netherlands

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Inger Sierevelt Department of Orthopaedic Surgery, Slotervaart Center of Orthopedic Research & Education (SCORE), The Netherlands

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Michel van den Bekerom Department of Orthopaedic Surgery, OLVG Hospital, The Netherlands

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Denise Eygendaal Department of Orthopaedic Surgery, Amphia Hospital, The Netherlands

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axillary fold became adherent to the humeral head. However, the existence of a true adhesion could not be confirmed in other studies. 6 Zuckerman et al formulated a descriptive consensus definition for FS: ‘a condition characterized by functional

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Nikolaos K. Paschos University of California, Davis, USA

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Stephen M. Howell University of California, Davis, USA

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-ACL reconstruction • Higher rate knee extension deficit due to adhesions • Higher incidence of tunnel widening • Electromechanical delay in knee flexors/weakness OA, osteoarthritis; ACL, anterior cruciate ligament Advantages of the patellar

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Maria-Pau Ginebra Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgical Engineering, Universitat Politècnica de Catalunya (UPC), Spain

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Montserrat Espanol Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgical Engineering, Universitat Politècnica de Catalunya (UPC), Spain

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Yassine Maazouz Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgical Engineering, Universitat Politècnica de Catalunya (UPC), Spain
Mimetis Biomaterials, Spain

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Victor Bergez Mimetis Biomaterials, Spain

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David Pastorino Mimetis Biomaterials, Spain

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nanoporosity, has been shown to play a very relevant a role in material resorption and bone formation. Small-size pores, of micrometric or nanometric size, have a critical effect on the biological response by influencing protein adsorption, cell adhesion and

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Shankar Aissvarya Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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King-Hwa Ling Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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Manohar Arumugam Department of Orthopaedics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
School of Medicine, Faculty of Medicine and Health Sciences, Taylor's University, Selangor, Malaysia

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Karuppiah Thilakavathy Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Genetics & Regenerative Medicine Research Group, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Malaysian Research Institute on Ageing (MyAgeing), Universiti Putra Malaysia, Serdang, Selangor, Malaysia

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from 12% to 23% ( 45 ). Integrin signalling pathway The integrin pathway controls the regulation of cell adhesion, spreading of cells and migration, proliferation, differentiation and ECM remodelling ( 46 ). The expression of integrin is

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Philippe Chiron Orthopédie Traumatologie, Secteur A, Batiment riquet, étage 5, CHU Toulouse, Toulouse Cedex 9, France

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Nicolas Reina Orthopédie Traumatologie, Secteur A, Batiment riquet, étage 5, CHU Toulouse, Toulouse Cedex 9, France

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adductor muscles and a possible sensation of adhesion. Secondarily, the shape of the femoral head can still be regularised by a medial approach with good functional results ( 1 , 46 ) ( Fig. 13 ). Figure 13 Malunion; late medial approach resection

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Ali-Asgar Najefi Foot & Ankle Unit, Royal National Orthopaedic Hospital, UK

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Luckshmana Jeyaseelan Foot & Ankle Unit, Royal National Orthopaedic Hospital, UK

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Matthew Welck Foot & Ankle Unit, Royal National Orthopaedic Hospital, UK

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. At three to five days post-injury, gentle range of motion can begin, with passive plantar flexion to prevent sesamoid adhesions while protecting the injured and healing plantar soft tissues. 16 The patient should be carefully followed in these

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Marianne Arner Department of Clinical Science and Education, Karolinska Institutet and Department of Hand surgery Södersjukhuset, Stockholm, Sweden

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-related problems, followed by scar adhesion/joint contracture after previous surgery. In 32% of reoperations due to complications, the primary surgery had been performed at another hospital, i.e. they were external complications. It should be emphasised, however

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Emmanuel Thienpont University Hospital Saint Luc, Brussels, Belgium

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bluntly and continued to the joint line to establish the medial gutter. This is repeated on the lateral side, with the pseudocapsule bluntly dissected, fibrous tissue removed from around the patella and any fibrous adhesions deep to the patella released

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