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AliSina Shahi The Rothman Institute at Thomas Jefferson University, Philadelphia, USA

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Javad Parvizi The Rothman Institute at Thomas Jefferson University, Philadelphia, USA

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Introduction Periprosthetic joint infection (PJI) is responsible for 25% of failed total knee arthroplasties 1 and 15% of revision total hip arthroplasties. 2 PJI has a huge economic burden on the health care system, and there will

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Donald J. Davidson Research Department of Orthopaedics and Musculoskeletal Sciences, University College London, London, UK
Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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David Spratt Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK

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Alexander D. Liddle Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, UK
MSK Lab, Imperial College London, London, UK

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Introduction Prosthetic joint infection (PJI) is one of the most feared complications of arthroplasty surgery due to its resistance to therapy with existing antibiotics. 1 It is a major cause of failure in arthroplasty, being the leading

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Corentin Pangaud Hôpital Sainte Marguerite, Aix Marseille Université, Marseille, France

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Matthieu Ollivier Hôpital Sainte Marguerite, Aix Marseille Université, Marseille, France

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Jean-Noël Argenson Hôpital Sainte Marguerite, Aix Marseille Université, Marseille, France

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Introduction Prosthetic joint infection (PJI) remains one of the most serious complications of knee prosthesis implantation. Its incidence is reported as between 0.5% and 2.0% according to the risk factors. 1 – 4 It is the commonest

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Pablo A. Slullitel Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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José I. Oñativia Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Martin A. Buttaro Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Marisa L. Sánchez Infectology Department, Italian Hospital of Buenos Aires, Argentina

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Fernando Comba Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Gerardo Zanotti Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Francisco Piccaluga Hip Surgery Unit, Italian Hospital of Buenos Aires, Argentina

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Introduction Being the third most common cause of revision surgery following primary total hip arthroplasty (THA), peri-prosthetic joint infection (PJI) constitutes one of the most undesired complications, with a prevalence of 0.3% to 2

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Jaime Esteban Servicio de Microbiología Clínica, Hospital Universitario Fundación Jiménez Díaz-IIS-Fundacion Jimenez Diaz, Universidad Autónoma de Madrid, Madrid, Spain

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Enrique Gómez-Barrena Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario La Paz-IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain

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Introduction Orthopaedic prosthetic joint infection (PJI) is a specific type of infection related to joint replacement and associated with biofilm formation on the surface of the inert implant. With an overall incidence between 1% and 5

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Tamer El-Sobky Division of Paediatric Orthopaedics, Department of Orthopaedic Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt

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Shady Mahmoud Division of Paediatric Orthopaedics, Department of Orthopaedic Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt

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from intravenous to oral antibiotic administration is currently a well-grounded practice. The growing clinical and microbiologic body of evidence on ‘high-risk’ children/neonates of acute osteoarticular infections warrants continual clinical extra

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Yangqi Xu Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia

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Tony B Huang Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia

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Michael A Schuetz Jamieson Trauma Institute, Metro North Hospital and Health Service, Queensland Health, Brisbane, Queensland, Australia
Department of Orthopaedic Surgery, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia
Queensland University of Technology (QUT), Brisbane, Queensland, Australia

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Peter F M Choong Department of Surgery, Melbourne Medical School, University of Melbourne, Victoria, Melbourne, Australia
Department of Orthopaedics, St. Vincent’s Hospital, Fitzroy, Victoria, Australia

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the ICARAUS group
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the ICARAUS group

Introduction Prosthetic joint infection (PJI) is one of the most devastating post-surgical complications for a patient undergoing a total joint arthroplasty (TJA). As one of the leading causes of joint replacement failure, PJI causes implant

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Tommaso Bonanzinga Humanitas University, Department of Biomedical Sciences, Milan, Italy
Humanitas Clinical and Research Center, Milan, Italy

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Matteo Carlo Ferrari Humanitas Clinical and Research Center, Milan, Italy

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Piergiuseppe Tanzi IRCCS Istituto Ortopedico Rizzoli; Università di Bologna, Dipartimento Scienze Biomediche e Neuromotorie, Bologna, Italy

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Filippo Vandenbulcke Humanitas University, Department of Biomedical Sciences, Milan, Italy
Humanitas Clinical and Research Center, Milan, Italy

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Akos Zahar Helios ENDO-Klinik, Hamburg, Germany

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Maurilio Marcacci Humanitas University, Department of Biomedical Sciences, Milan, Italy
Humanitas Clinical and Research Center, Milan, Italy

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Introduction Prosthetic joint infections (PJI) occur in 0.7% to 2.4% of patients and are responsible for 15% of failed total hip arthroplasties and 25% of revision total knee arthroplasties. 1 , 2 Almost any microorganism can cause PJI

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Andy Craig Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK

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S W King Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK

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B H van Duren Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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V T Veysi Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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S Jain Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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J Palan Department of Trauma & Orthopaedics, Leeds Teaching Hospitals, Leeds, UK
Leeds Institute of Rheumatic Musculoskeletal Medicine (LIRMM), Chapel Allerton Hospital, Leeds, UK

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Joint Registry (NJR) data indicating 10-year revision rates of approximately 2% for a number of commonly used prostheses ( 6 ). Nonetheless, prosthetic joint infection (PJI) remains a devastating complication. Of all single- and first-stage revisions (of

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Hua Luo Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yongwei Su The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China

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Feng Xue Department of Orthopaedics, Fengxian District Central Hospital, Shanghai, People’s Republic of China

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Zhenghua Hong Department of Orthopaedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Introduction Surgery site infections (SSIs) is one of the common complications affecting surgical management and patient recovery. Related studies report that the incidence of SSIs is 1–14% ( 1 , 2 , 3 , 4 , 5 ). The incidence of SSIs is

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