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Gautier Beckers Department of Surgery, Hôpital Maisonneuve-Rosemont, Montréal University, Montréal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA

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Vincent Massé Department of Surgery, Hôpital Maisonneuve-Rosemont, Montréal University, Montréal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA
Clinique Orthopédique Duval, Laval, Quebec, Canada

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Pascal-André Vendittoli Department of Surgery, Hôpital Maisonneuve-Rosemont, Montréal University, Montréal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA
Clinique Orthopédique Duval, Laval, Quebec, Canada

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Mina W Morcos Department of Surgery, Hôpital Maisonneuve-Rosemont, Montréal University, Montréal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA

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kinematic alignment (rKA) principles since it decreases the need for soft tissues release and further bleeding ( 41 , 42 ). Although the efficiency of navigation to decrease blood loss has not been proven in the general population, the authors consider that

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Marilena Giannoudi Department of Cardiology, Bradford Teaching Hospitals NHS Trust, Bradford, UK
Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK

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Peter V Giannoudis Academic Department of Trauma and Orthopaedics, Floor D, Clarendon Wing, LGI, University of Leeds, Leeds, UK
NIHR Leeds Biomedical Research Centre, Chapel Allerton Hospital, Leeds, UK

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medications and a final group comprised patients not on antiplatelet therapy. They reported that patients on DAPT were prone to increase intraoperative blood loss, compared to those on single or no therapy. Just as before, they described no significant

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Chaojun Shen Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Tongyou Qu Department of Pharmacy, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang China

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Lin Chen Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yue Sun Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang China

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surgeries. Systemic TXA administered at the outset of surgery reduces intraoperative blood loss and blood loss from drained spaces such as the knee or mediastinum but may be contraindicated in patients with intravascular stents or thrombophilia ( 3

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Guido Grappiolo IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Fondazione Livio Sciutto Onlus, Campus Savona - Università degli Studi di Genova, Via

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Edoardo Guazzoni IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Department of Orthopaedics and Traumatology, IRCCS Fondazione Policlinico San Matteo, University of Pavia, Pavia, Italy

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Francesco Manlio Gambaro Fondazione Livio Sciutto Onlus, Campus Savona - Università degli Studi di Genova, Via
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy

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Mattia Loppini IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Fondazione Livio Sciutto Onlus, Campus Savona - Università degli Studi di Genova, Via
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy

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-014-1946-3 ) 4 Loppini M Della Rocca A Ferrentino D Pizzi C & Grappiolo G . Blood loss in primary total hip arthroplasty with a short versus conventional cementless stem: a retrospective cohort study . Archives of Orthopaedic and Trauma Surgery 2020

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Benedikt Johannes Braun Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Jörg Holstein Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Tobias Fritz Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Nils Thomas Veith Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Steven Herath Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Philipp Mörsdorf Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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Tim Pohlemann Department of Trauma, Hand and Reconstructive Surgery, Saarland University Hospital, Homburg, Germany

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, when compared to healthy 20-year-olds. 10 This is associated with a reduced reserve of endogenous catecholamines, limiting the body’s ability to respond to shock and the challenge of blood loss. Further complicating volume response is the fact that

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Pieter Bas de Witte Department Orthopedic Surgery, LUMC, Leiden, the Netherlands

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Christiaan J A van Bergen Department Orthopedic Surgery, Amphia, Breda, the Netherlands

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Babette L de Geest Knowledge Institute of Medical Specialists, Utrecht, the Netherlands

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Floor Willeboordse Knowledge Institute of Medical Specialists, Utrecht, the Netherlands

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Joost H van Linge Juliana Children’s Hospital, The Hague & Reinier HAGA Orthopaedic Centre, Zoetermeer and Delft, the Netherlands

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Yvon M den Hartog Department Orthopedic Surgery, MST, Enschede, the Netherlands

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Magritha (Margret) M H P Foreman-van Drongelen Department Hip Sonography, Diagnostiek voor U, Eindhoven, The Netherlands

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Renske M Pereboom Dutch Hip Patient Association “Vereniging Afwijkende Heupontwikkeling”, Nijkerk, the Netherlands

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Simon G F Robben Department Radiology, Maastricht University Medical Center, Maastricht, the Netherlands

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Bart J Burger Department Orthopedic Surgery, North West Hospital Group, Alkmaar, the Netherlands

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M Adhiambo Witlox Department Orthopedic Surgery, CAPHRI Care and Public Health Research Institute, Maastricht University Medical Center, Maastricht, the Netherlands

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Melinda M E H Witbreuk Department Orthopedic Surgery OLVG, AUMC Amsterdam, the Netherlands

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necrosis (AVN) and neuropathy), and secondary procedures. Additionally, with regards to surgery (PICO research question 3), blood loss and operative time were considered important outcomes. Search strategy and study selection In the development

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Xun Wang Department of Orthopedics, Center for Plastic & Reconstructive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China
Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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Aiqi Zhang Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

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Wenchao Yao Department of Orthopaedics, the First People's Hospital of Chun'an County, Hangzhou, Zhejiang, China

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Haiyan Qiu Department of Endocrinology, Afliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

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Fabo Feng Department of Orthopedics, Center for Plastic & Reconstructive Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China

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clinical outcomes of patients undergoing MIS-TLIF or ALIF for isthmic spondylolisthesis and revision, and found that ALIF only significantly increased operative time and intraoperative blood loss, whereas there was no significant difference in long

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Philippe Hernigou Hôpital Henri Mondor, University Paris East, Paris, France

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Victor Housset Hôpital Henri Mondor, University Paris East, Paris, France

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Jacques Pariat Hôpital Henri Mondor, University Paris East, Paris, France

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Arnaud Dubory Hôpital Henri Mondor, University Paris East, Paris, France

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Charles Henri Flouzat Lachaniette Hôpital Henri Mondor, University Paris East, Paris, France

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blood loss requiring several transfusions and resulting in transfusion reactions. Given the frequency of antigen mismatch between mostly Caucasian donors and African-origin recipients and in an attempt to prevent alloimmunization, blood products which

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Michael J. Raschke Department of Trauma, Hand and Reconstructive Surgery, Westphaelian Wilhelms University Muenster, Waldeyer Strasse 1, 48149 Muenster, Germany

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Christoph Kittl Department of Trauma, Hand and Reconstructive Surgery, Westphaelian Wilhelms University Muenster, Waldeyer Strasse 1, 48149 Muenster, Germany

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Christoph Domnick Department of Trauma, Hand and Reconstructive Surgery, Westphaelian Wilhelms University Muenster, Waldeyer Strasse 1, 48149 Muenster, Germany

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cause aseptic leukocyte proliferation and macrophage activation. 33 ‘To tourniquet or not to tourniquet?’ Using a tourniquet during surgery may improve visibility, reduce intra-operative blood loss and swelling during surgery, and may support

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain

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, the high risk of infection (7% on average) is a concern ( Fig. 8 ). 27 – 30 Reported results of primary TKR in haemophilia are satisfactory. 27 – 31 It is paramount today to use a multimodal blood-loss prevention approach (MBLPA) including

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