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Maria Anna Smolle Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Joanna Szkandera Division of Clinical Oncology, Internal Medicine, Medical University of Graz, Graz, Austria

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Dimosthenis Andreou Division of Orthopaedic Oncology and Sarcoma Surgery, Helios Klinikum Bad Saarow, Sarcoma Center Berlin-Brandenburg, Berlin, Germany

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Emanuela Palmerini Chemotherapy Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna University, Bologna, Italy

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Marko Bergovec Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Andreas Leithner Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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radiotherapy seems to be more effective regarding LC in liposarcoma and undifferentiated pleomorphic sarcoma (UPS) as compared with malignant peripheral nerve sheath tumour or synovial sarcoma. 65 , 66 Another locoregional treatment modality constitutes

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Pierre Hoffmeyer Editor in Chief, EFORT Open Reviews

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become freely available, R numbers were low, hospitals were slowly emptying, the sun was shining, its heat melting the malignant microscopic lipid droplets. But deep down we all knew it was only a reprieve. So right we were. Autumn brought back the full

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Zsombor Panti Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Mihai Nica Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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-sparing surgery dominates the modern management of primary malignant bone tumours. For the reconstruction of massive bone defects resulted after the resection of bone sarcoma standard nowadays is the use of modular endoprosthetic systems, performed usually in

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Joaquim Soares do Brito Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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André Spranger Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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Paulo Almeida Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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José Portela Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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Irene Barrientos-Ruiz Orthopedics Department, University Hospital of La Paz, Madrid

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Introduction Giant cell tumour (GCT) of bone is a relatively rare, locally aggressive benign neoplasm associated with a wide pathological spectrum, ranging from latent benign to highly recurrent and, occasionally, malignant metastatic

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Stijn E. W. Geraets Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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P. Koen Bos Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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Johan van der Stok Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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Blood loss Transfusion requirements 3 11 Kickuth et al, 2008 30 Case-cohort Multiple: renal cell carcinoma (18), malignant melanoma (1), leiomyosarcoma (1), hepatocellular carcinoma (1), prostate carcinoma (1) Femur (14) Humerus (4

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Guillermo Droppelmann Research Center on Medicine, Exercise, Sport and Health, MEDS Clinic, Santiago, RM, Chile
Health Sciences PhD Program, Universidad Católica de Murcia UCAM, Murcia, Spain
Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA

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Constanza Rodríguez Facultad de Medicina, Universidad Finis Terrae, Santiago, RM, Chile

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Carlos Jorquera Facultad de Ciencias, Escuela de Nutrición y Dietética, Universidad Mayor, Santiago, RM, Chile

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Felipe Feijoo School of Industrial Engineering, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile

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Algorithm Cohen et al. ( 17 ) France Rx Wrist fracture 637 1917 206 41 17 373 Bone View (Gleamer) Georgeanu et al. ( 18 ) Romania MRI Malignant bone tumors 23 2106 80 20 4 63 Res-Net 50 Hess

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Filippo Familiari Department of Orthopaedics and Traumatology, Villa del Sole Clinic, Italy

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Jorge Rojas Division of Shoulder Surgery, Department of Orthopaedic Surgery, The Johns Hopkins University, USA

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Mahmut Nedim Doral Department of Orthopaedics and Traumatology, Hacettepe University, Turkey

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Gazi Huri Department of Orthopaedics and Traumatology, Hacettepe University, Turkey

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Edward G. McFarland Division of Shoulder Surgery, Department of Orthopaedic Surgery, The Johns Hopkins University, USA

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malignant bone tumours, including allograft, arthrodesis and shoulder arthroplasties. 82 However, a prerequisite for the ability to implant a RTSA in these cases requires preservation of the axillary nerve and deltoid muscle to be successful. 6 , 83

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Catalin Cirstoiu Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Bogdan Cretu Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Sergiu Iordache Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Mihnea Popa Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Bogdan Serban Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Adrian Cursaru Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Orthopedics and Traumatology Department, University Emergency Hospital Bucharest, Bucharest, Romania

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Introduction The most common malignant bone tumors are bone metastases, which are caused by visceral tumors and primary hematopoietic neoformations. With the evolution of oncological treatments, which have led to increased survival of cancer

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Bogdan Serban Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Adrian Cursaru Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Cornelia Nitipir Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania

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Cristina Orlov-Slavu Department of Oncology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Elias University Emergency Hospital, Bucharest, Romania

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Catalin Cirstoiu Department of Orthopedics and Traumatology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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relapsed limb sarcoma, having been adapted from the treatment options for malignant melanoma. It technically differs from ILP in that it creates much slower blood circulation in the limb, and the limb is intensely hypoxic during the procedure. In addition

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Han Ling Tan Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Tunku Sara Ahmad Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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C Sankara Kumar Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Yohan Khirusman Adnan Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Lai Meng Looi Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Jayaletchumi Gunasagaran Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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, 10 , 11 ). Malignant transformation has never been reported in this tumor. There are other differential tumors with myxoid histological appearance or tumors with distal extremity predilection ( Tables 1 and 2 ). Table 1 Summarized list of

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