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E Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain
Osteoarticular Surgery Research, Hospital La Paz Institute for Health Research – IdiPAZ (La Paz University Hospital – Autonomous University of Madrid), Madrid, Spain

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Alberto D Delgado-Martínez Department of Orthopaedic Surgery, Hospital Universitario de Jaén, Jaén, Spain
Department of Surgery, University of Jaén, Jaén, Spain

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Javier De Andrés-Ares Department of Anesthetics, Pain Unit, La Paz University Hospital, Madrid, Spain

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patients had excellent to good functional improvement. RFMT was a dependable modality for managing recalcitrant lateral epicondylitis of the elbow with excellent long-run outcomes ( 53 ). Lower limb RF treatments RF in knee OA According to

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SaTia T. Sinclair Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Ahmed K. Emara Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Melissa N. Orr Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Kara M. McConaghy Case Western Reserve University School of Medicine, Cleveland, Ohio, United States

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Alison K. Klika Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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Nicolas S. Piuzzi Cleveland Clinic Foundation, Department of Orthopedic Surgery, Cleveland, Ohio, United States

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such as diabetes, 8 respiratory disease, 8 chronic kidney disease, 9 and depression 10 have all been associated with adverse clinical outcomes, including infection, 8 extended hospital stay, 9 and mortality, 10 after

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Petra Izakovicova HELIOS Klinik Zerbst/Anhalt, Germany

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Olivier Borens Service of Orthopaedics and Traumatology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland

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Andrej Trampuz Charité – Universitätsmedizin Berlin, Corporate Member of Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Center for Musculoskeletal Surgery (CMSC), Berlin, Germany

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-stage procedures, 78 two-stage revision can be considered overtreatment for a large number of PJI patients and relates to higher morbidity, longer hospital stays and time of immobilization, worse functional outcome and higher health care costs. 79 , 80

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Low-dose dexamethasone during arthroplasty

What do we know about the risks?

Jessica T. Wegener Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Tim Kraal Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Markus F. Stevens Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Markus W. Hollmann Department of Anesthesiology, Academic Medical Center (AMC), University of Amsterdam, The Netherlands

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Gino M.M.J. Kerkhoffs Department of Orthopedic Surgery, Academic Medical Center and the Orthopedic Research Center Amsterdam, The Netherlands

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Daniël Haverkamp Department of Orthopedic Surgery, Slotervaart Ziekenhuis, Amsterdam, The Netherlands

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Bergeron * 2009 RCT I Functional outcome Harris hip score Kardash * 2008 RCT I Dynamic pain Numeric rating scale Mathiesen 2008 RCT I Analgesic effect of pregabalin and dexamethason Morphine consumption in mg

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Di Zhao The Second Clinical School of Guangzhou University of Chinese Medicine, Guangzhou, China
Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China

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Ling-feng Zeng The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China
Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China

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Gui-hong Liang The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China
Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China

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Jian-ke Pan The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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Ming-hui Luo The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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Yan-hong Han The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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Jun Liu Bone and Joint Research Team of Degeneration and Injury, Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China
Guangdong Second Traditional Chinese Medicine Hospital (Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine), Guangzhou, China
The fifth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China

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Wei-yi Yang The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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with incomplete data. Data extraction Two researchers independently extracted the data, which included the first author, year of publication, type and dose of intervention, trial size, patient sex, age, outcome measures and duration of follow

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Joseph Genevière Faculty of Medicine, University of Geneva, Geneva, Switzerland
Co-first authors and equal contributors

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Shawna McCallin Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors

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Angela Huttner Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

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Truong-Thanh Pham Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Domizio Suva Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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evaluate safety. The Population, Intervention, Comparator and Outcome (PICO) inclusion criteria are summarized in Fig. 1 . Fig. 1 PICO entry criteria. Note . PICO, Population, Intervention, Comparator and Outcome; PT, phage therapy

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Xiang-Dong Wu Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Fourth Clinical College of Peking University, Beijing, China

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Yixin Zhou Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Fourth Clinical College of Peking University, Beijing, China

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Hongyi Shao Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Fourth Clinical College of Peking University, Beijing, China

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Dejin Yang Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Fourth Clinical College of Peking University, Beijing, China

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Sheng-Jie Guo Department of Orthopaedic Surgery, Beijing Jishuitan Hospital, Fourth Clinical College of Peking University, Beijing, China

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Wei Huang Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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planning and robotic-arm-assisted bone cutting may comparatively lead to better implant positioning, higher functional scores, and better clinical outcomes. Thus, along with the technological advancement and familiarity with the procedure, surgeons believe

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James R. Berstock University of British Colombia Department of Orthopaedics, Gordon & Leslie Diamond Health Care Centre, Vancouver, British Columbia, Canada

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Michael R. Whitehouse Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Southmead Hospital, Bristol, UK
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and University of Bristol, Bristol, UK

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example, inadequate blinding of patients has more of a deleterious effect on subjective outcomes such as satisfaction or functional score than it does for objective outcomes such as mortality. The risk of bias is usually summarized in a table ( Table 1

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Maria Anna Smolle Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Lukas Leitner Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Nikolaus Böhler Department for Orthopedics and Traumatology, Kepler University Hospital GmbH, Linz, Austria

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Franz-Josef Seibert Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Mathias Glehr Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Andreas Leithner Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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functional outcomes of vascularized bone graft in the treatment of scaphoid non-union . PLoS One 2018 ; 13 : e0197768 . 90. Hirche C Heffinger C Xiong L et al. The 1,2-intercompartmental supraretinacular artery vascularized bone

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Anne Lübbeke Division of Orthopaedic Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK

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Andrew J Carr Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK

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Pierre Hoffmeyer Division of Orthopaedic Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland

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and solutions for healthcare problems. The positive impact of registries on healthcare outcomes and healthcare processes has been demonstrated. 2 Clinical registries are an essential part of the learning healthcare system. 3 They collect pre

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