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Mattia Loppini Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy
IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Fondazione Livio Sciutto Onlus, Campus Savona – Università degli Studi di Genova, Savona, Italy

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Francesco Manlio Gambaro Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy

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Rob G H H Nelissen Landelijke Registratie Orthopedische Implantaten (Dutch Arthroplasty Register), ’s Hertogenbosch, The Netherlands
Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands

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Guido Grappiolo IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Fondazione Livio Sciutto Onlus, Campus Savona – Università degli Studi di Genova, Savona, Italy

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for special cases such as metal-on-metal (MoM) THA or small head size ( 5 , 12 , 13 ). Concerning the quality of evidence behind them, these guidelines were not evidence based but drafted from expert consensus. Therefore, the level of recommendation

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William G. Blakeney Department of Surgery, CIUSSS-de-L’Est-de-L’Ile-de-Montréal, Hôpital Maisonneuve Rosemont, Montréal, Québec, Canada
Department of Surgery, Albany Health Campus, Albany, Australia

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Jean-Alain Epinette Clinique Médico-chirurgicale, Bruay la Buissière, France

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Pascal-André Vendittoli Department of Surgery, Albany Health Campus, Albany, Australia
Department of Surgery, Université de Montréal, Montréal, Québec, Canada

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future of these ‘minimalist’ inserts. Using LDH with hard metal-on-metal bearings did not come without problems, and in particular the appearance of ‘trunnionosis’ and associated secondary local adverse reaction to metal debris. 16 Another LDH joint

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Claus Varnum The Danish Hip Arthroplasty Register
Department of Orthopaedic Surgery, Vejle Hospital, Vejle, Denmark

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Alma Bečić Pedersen Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark

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Ola Rolfson The Swedish Hip Arthroplasty Register
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Cecilia Rogmark The Swedish Hip Arthroplasty Register
Lund University, Skåne University Hospital, Department of Orthopedics, Malmö, Sweden

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Ove Furnes The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
Department of Clinical Medicine, University of Bergen, Bergen, Norway

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Geir Hallan The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
Department of Clinical Medicine, University of Bergen, Bergen, Norway

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Keijo Mäkelä The Finnish Arthroplasty Register
Department of Orthopaedics and Traumatology, Turku University Hospital, Turku, Finland

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Richard de Steiger Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), Adelaide, Australia
Department of Surgery, Epworth HealthCare, University of Melbourne, Melbourne, Australia

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Martyn Porter The National Joint Registry of England, Wales, Northern Ireland and Isle of Man
Centre for Hip Surgery, Wrightington Hospital, Wrightington, Wigan and Leigh NHS Trust, Lancashire, United Kingdom

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Søren Overgaard The Danish Hip Arthroplasty Register
Orthopaedic Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark

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register. For example, owing to Swedish surgeons’ cautious attitude towards undocumented new concepts, Sweden avoided the catastrophes associated with metal-on-metal (MoM) implants. Today, six different stem designs account for > 92% of all femoral

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Olivier Guyen Department of Orthopaedic Surgery, Lausanne University Hospital, Lausanne, Switzerland

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primary hip arthroplasties performed in patients presumed at high risk for dislocation. Available larger diameter material combinations include metal or ceramic on highly cross-linked polyethylene and metal-on-metal. The use of large head metal-on-metal

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Theofilos Karachalios School of Health Sciences, Faculty of Medicine, University of Thessalia, University General Hospital of Larissa, Mezourlo Region, 41110 Larissa, Greece

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George Komnos Orthopaedic Department, University General Hospital of Larissa, Greece

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Antonios Koutalos Orthopaedic Department, University General Hospital of Larissa, Greece

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in vivo . 11 Hard-on-hard bearings, such as ceramic-on-ceramic (CoC), with survival rates of approximately 97% at ten years, or metal-on-metal (MoM), with survival rates of approximately 90% at ten years (in the best reports), were initially

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Anne Lübbeke Division of Orthopaedic Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK

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James A. Smith Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK

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Daniel Prieto-Alhambra Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK

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Andrew J. Carr Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK

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alone. 1 The development and implementation of medical devices has been questioned for reasons related to widespread clinical use of new devices without evidence of their safety and performance (e.g. metal-on-metal hip prostheses), 2 limited

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Carsten Perka Center for Musculoskeletal Surgery, Charité Medical University Center, Berlin, Germany

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Maziar Mohaddes Hässleholms Hospital, Region Skåne, Hässleholm, Sweden
Orthopedics, Faculty of Medicine, Department of Clinical Sciences, Lund University, Malmö, Sweden

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Luigi Zagra Hip Department, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy

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Axel Ekkernkamp BG Klinikum Unfallkrankenhaus Berlin gGmbH, Berlin, Germany
BG Kliniken – Klinikverbund der gesetzlichen Unfallversicherung gGmbH, Berlin, Germany

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Niklas Keller Harding Center for Risk Literacy, University of Potsdam, Faculty of Health Sciences, Potsdam, Germany

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Dirk Stengel BG Kliniken – Klinikverbund der gesetzlichen Unfallversicherung gGmbH, Berlin, Germany

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investigations on alumina–zirconia prior to approval by the FDA, EMEA, and other regulatory bodies. We included studies published until May 1, 2023. We decided to exclude research incorporating metal-on-metal (MoM) pairings unless relevant information on CoC

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Keith Tucker Orthopaedic Data Evaluation Panel (ODEP), Norwich, UK

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Klaus-Peter Günther University Centre of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Germany

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Per Kjaersgaard-Andersen Department of Orthopaedics, Vejle Hospital, South Danish University, Vejle, Denmark

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Jörg Lützner University Centre of Orthopedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Germany

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Jan Philippe Kretzer Laboratory of Biomechanics and Implant Research, Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Heidelberg, Germany

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Rob G.H.H. Nelissen Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands

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Toni Lange Center for Evidence-based Healthcare, University Hospital Carl Gustav Carus and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Germany

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Luigi Zagra IRCCS Istituto Ortopedico Galeazzi, Hip Department, Milan, Italy

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-on-soft’ and ‘hard-on-hard’. The former included metal or ceramic heads on polythene and the latter ‘metal-on-metal’ or ‘ceramic-on-ceramic’. The best performing construct in the NJR at the time of publishing was a cemented Exeter Stem and the Charnley Elite

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Anne Lübbeke Division of Orthopaedic Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK

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Andrew J Carr Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK

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Pierre Hoffmeyer Division of Orthopaedic Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland

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available resources. Another use of registry data relates to the prevention of adverse events and threats to patients and to public health. Tissue responses from cobalt ions produced from excessive wear in metal-on-metal hip arthroplasty or implant

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Bülent Atilla Hacettepe University Faculty of Medicine, Ankara, Turkey

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disadvantages of the many bearing surface options in total hip arthroplasty are under investigation; the most appropriate choice should be individualised to each patient. Following the wide-ranging use of metal-on-metal surfaces which have demonstrated local

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