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Djandan Tadum Arthur Vithran Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

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Anko Elijah Essien Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China

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Masoud Rahmati Research Centre on Health Services and Quality of Life, Aix Marseille University, Marseille, France
Department of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad, Iran
Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, Vali-E-Asr University of Rafsanjan, Rafsanjan, Iran

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Michael Opoku Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China

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Dong Keon Yon Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, Republic of Korea
Department of Pediatrics, Kyung Hee University College of Medicine, Seoul, Republic of Korea

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Guillermo F López Sánchez Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain

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Ai Koyanagi Research and Development Unit, Parc Sanitari Sant Joan de Deu, Barcelona, Spain

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Lee Smith Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK

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Jae Il Shin Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea

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Wenfeng Xiao Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

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Shuguang Liu Department of Joint Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, China

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Yusheng Li Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, China
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China

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, to critically compare teriparatide’s efficacy in reducing fracture incidence with that of placebo and other established osteoporosis medications, defining its clinical value for individuals at heightened risk of fractures; and finally, to thoroughly

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Christof Berberich Department of Medical Training and Education, Heraeus Medical GmbH, Wehrheim, Germany

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Pablo Sanz-Ruiz Department of Traumatology and Orthopaedic Surgery, General University Hospital Gregorio Marañón, Madrid, Spain

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resistance, the use of antibiotic-loaded bone cement remains controversial. The aim of this review is to summarize and discuss the available evidence derived from experimental, preclinical and clinical studies on whether antibiotic-loaded bone cement does

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Leonard Christianto Singjie Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia
Faculty of Medicine, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

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Reynaldo Halomoan Faculty of Medicine, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

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Ifran Saleh Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

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Endrotomo Sumargono Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia

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Erica Kholinne Department of Orthopedic Surgery, St. Carolus Hospital, Jakarta, Indonesia
Faculty of Medicine, Universitas Trisakti, Jakarta, Indonesia

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, we sought to analyze the efficacy of aspirin compared to that of other anticoagulants (LMWH and factor Xa inhibitors) for VTE prophylaxis in patients undergoing major orthopedic surgeries, including trauma patients ( 1 , 12 ). Methods This

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Joseph Genevière Faculty of Medicine, University of Geneva, Geneva, Switzerland
Co-first authors and equal contributors

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Shawna McCallin Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors

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Angela Huttner Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

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Truong-Thanh Pham Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Domizio Suva Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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, given the publication bias inherent to this type of literature. Clinical trials are the next step required to confirm the efficacy of PT in bone and joint infections and to define to what extent they are indicated in situations of therapeutic failure

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Jacobien H.F. Oosterhoff Department of Orthopaedic Surgery, Amsterdam UMC, University of Amsterdam, the Netherlands
Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

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Job N. Doornberg Department of Orthopaedic Surgery, Amsterdam UMC, University of Amsterdam, the Netherlands
Department of Orthopaedic & Trauma Surgery, Flinders Medical Centre, Flinders University, Adelaide, SA, Australia

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Machine Learning Consortium Members of the Machine Learning Consortium: Paul Algra, Michel van den Bekerom, Mohit Bhandari, Michiel Bongers, Charles Court-Brown, Anne-Eva Bulstra, Geert Buijze, Sofia Bzovsky, Neil Chen, Job Doornberg, Andrew Duckworth, J. Carel Goslings, Benjamin Gravesteijn, Olivier Groot, Gordon Guyatt, Laurent Hendrickx, Dirk-Jan Hofstee, Frank IJpma, Ruurd Jaarsma, Stein Janssen, Paul Jutte, Aditya Karhade, Lucien Keijser, Gino Kerkhoffs, David Langerhuizen, Jonathan Lans, Wouter Mallee, Matthew Moran, Margaret McQueen, Marjolein Mulders, Miryam Obdeijn, Tarandeep Oberai, Jacobien H.F. Oosterhoff, Rudolf Poolman, David Ring, Paul Tornetta III, Joseph Schwab, Emil H. Schemitsch, Niels Schep, Inger Schipper, Bram Schoolmeesters, Marc Swiontkowski, David Sanders, Sheila Sprague, Ewout Steyerberg, Stephen D. Walter, Monique Walenkamp

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identify pre-operative risk of post-operative delirium in hip fracture surgery 12 and the ML algorithm will likely improve the efficiency of a screening programme aimed at identifying patients at risk for delirium. However, the clinical efficacy of the

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Mohammad Poursalehian Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Orthopedic Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

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Sina Hajiaghajani Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Orthopedic Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

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Mohammad Ayati Firoozabadi Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Orthopedic Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

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Davood Dehghani Ashkezari Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Orthopedic Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

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Seyed Mohammad Javad Mortazavi Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Orthopedic Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

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comprehensive review summarizes the existing body of literature to provide an understanding of the KFs’ biomechanics, their role in knee stability, and their impact on clinical practices. This review offers a substantial contribution to the orthopedic community

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Antal Imre Department of Orthopaedics, Semmelweis University, Budapest, Hungary

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Sápi Zoltán Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest

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Szendrői Miklós Department of Orthopaedics, Semmelweis University, Budapest, Hungary

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study of denosumab efficacy and safety in patients with breast cancer-related bone metastases . Journal of Clinical Oncology 2007 25 4431 – 4437 . ( https://doi.org/10.1200/JCO.2007.11.8604 ) 44. Bussiere JL Pyrah I Boyce R Branstetter D

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Abdel Rahim Elniel Leeds Teaching Hospitals Trust, UK

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Peter V. Giannoudis Academic Department of Trauma and Orthopaedics, Leeds Teaching Hospitals, University of Leeds, UK; NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, UK

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classification of fractures and soft-tissue injury, but more time is needed to assess its efficacy in real-life application. Table 1. Parameters of the OTA open fracture classification 9 Parameter Score Injury to skin Small

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Yu Ren Department of Pharmacy, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hui Yu Department of Hematology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China
Department of Hematology, Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, China

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Zhangfu Wang Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Wenjun Pan Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Lin Chen Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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complications, type and quality of water used, and wound complications. However, because it is clinically difficult to determine the exact probability of infecting a sutured wound, it is difficult to fully determine whether bathing truly increases the

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Gerardo Fusco Humanitas University, Department of Biomedical Sciences, Milan, Italy
IRCCS Humanitas Research Hospital, Milan, Italy
These authors contributed equally to the article and should both be considered first authors

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Francesco M. Gambaro Humanitas University, Department of Biomedical Sciences, Milan, Italy
IRCCS Humanitas Research Hospital, Milan, Italy
These authors contributed equally to the article and should both be considered first authors

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Berardo Di Matteo Humanitas University, Department of Biomedical Sciences, Milan, Italy
First Moscow State Medical University – Sechenov University, Moscow, Russia

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Elizaveta Kon Humanitas University, Department of Biomedical Sciences, Milan, Italy
IRCCS Humanitas Research Hospital, Milan, Italy

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in the analysis of clinical outcomes. This limitation in the ability of clinical studies to investigate the real efficacy of PRP may be overcome by future studies employing a novel coding system as proposed by Kon et al. 29 An example of PRP

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