IRCCS Humanitas Research Hospital, Milan, Italy
These authors contributed equally to the article and should both be considered first authors
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IRCCS Humanitas Research Hospital, Milan, Italy
These authors contributed equally to the article and should both be considered first authors
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First Moscow State Medical University – Sechenov University, Moscow, Russia
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IRCCS Humanitas Research Hospital, Milan, Italy
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Introduction Osteoarthritis (OA) is a degenerative disease with a tendency to worsen over time, characterized by articular cartilage degradation, subchondral damage, and bone remodelling, most commonly affecting weight-bearing joints such as
Walsall Manor Hospital, Moat Road, Walsall, WS2 9PS, UK
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Walsall Manor Hospital, Moat Road, Walsall, WS2 9PS, UK
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meniscus is an intra-articular structure composed primarily of type 1 collagen. Its main functions are shock absorption, proprioception, lubrication and joint stability. 30 It is vulnerable to repetitive injury which can predispose to osteoarthritis
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can have negative effects such as pro-inflammatory cytokines, matrix metalloproteinases (MMPs) and interleukin-1β (IL-1β). 48 For example, Browning et al 49 demonstrated an increase in MMP-1 and MMP-3 in osteoarthritis (OA) synoviocytes
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was gathered. The indications were divided into five categories: acute fracture, primary osteoarthritis, inflammatory arthritis, post-traumatic sequelae and other . The category acute fracture was defined as all categories specifying acute trauma
Department of Surgery, Universidad de La Laguna, Tenerife, Spain
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University of Basel, Basel, Switzerland
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Department of Orthopedic and Rehabilitation, University of Iowa, Iowa, USA
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Department of Surgery, Universidad de La Laguna, Tenerife, Spain
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Department of Surgery, Universidad de Sevilla, Sevilla, Spain
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Introduction Ankle osteoarthritis (OA) is a chronic disease affecting approximately 1% of the world population, with an estimated incidence of 30 cases per 100 000 inhabitants, and corresponds to between 2 and 4% of all patients with general
South West London Elective Orthopaedic Centre, UK
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instructional review aims to clarify and classify the SHRs that are commonly encountered in patients with hip osteoarthritis (OA). Spino-pelvic parameters In order to understand and define the SHR, it is important to understand the significance of the
Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, Pieve Emanuele, Milan, Italy
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Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, Pieve Emanuele, Milan, Italy
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Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, Pieve Emanuele, Milan, Italy
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Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, Pieve Emanuele, Milan, Italy
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Department of Traumatology, Orthopaedics and Disaster Surgery, Moscow, Russia
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Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, Pieve Emanuele, Milan, Italy
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Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, Pieve Emanuele, Milan, Italy
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Introduction Osteoarthritis (OA), most commonly developing in the knee joint, is the main cause of disability in older adults and is characterized by pain, loss of function, and decreased quality of life (QoL). Nowadays, an estimated 240
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been little further interest. While research into osteoarthritis has focused mainly on cartilage and synovium at the mechanical, macroscopic, microscopic, cellular, molecular and genetic levels, subchondral vascular aspects have escaped attention ( 12
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Introduction Osteoarthritis (OA) is a degenerative disease that affects joints, especially hip and knee. Population aging leads to a progressive increase in the incidence of this disease. Half of the world's population aged 65 and older suffer
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Introduction Osteoarthritis of the carpometacarpal joint of the thumb (CMC-1) is a common problem and surgical treatment is indicated when conservative measures fail to provide sufficient relief. Of the many surgical treatment options, no