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Theofilos Karachalios Department of Orthopaedics and Musculoskeletal Trauma, University General Hospital of Larissa, Greece
School of Health Sciences, Faculty of Medicine, University of Thessalia, Larissa, Greece

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George A. Komnos Department of Orthopaedics and Musculoskeletal Trauma, University General Hospital of Larissa, Greece

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Society Score (KSS) scales are mostly used. 11 – 14 , 16 , 17 It has to be stressed that Jafari et al have shown that 25 (22%) of their 112 septic total hip arthroplasty (THA) revisions failed due to reinfection and 21 (19%) failed due to other

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Joseph Genevière Faculty of Medicine, University of Geneva, Geneva, Switzerland
Co-first authors and equal contributors

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Shawna McCallin Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Co-first authors and equal contributors

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Angela Huttner Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland

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Truong-Thanh Pham Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Infectious Diseases, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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Domizio Suva Faculty of Medicine, University of Geneva, Geneva, Switzerland
Division of Orthopaedics and Trauma Surgery, Bone Infection Unit, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland

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used thereafter until the widespread use of antibiotics in the 1940s, after which they were mostly abandoned in Western medicine. 16 Today, PT is gaining a renewed interest to treat infections against which antibiotics have failed, an increasingly

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Giorgio Perino Department of Orthopedics and Orthopedic Surgery, University Medicine Greifswald, Greifswald, Germany

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Ivan De Martino Division of Orthopaedics and Traumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy

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Lingxin Zhang Department of Pathology and Laboratory Medicine, Sinai Health System, Toronto, Canada

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Zhidao Xia Centre for Nanohealth, Swansea University Medical School, Singleton Park, Swansea, UK

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Jiri Gallo Department of Orthopaedics, Faculty of Medicine and Dentistry, University Hospital, Palacky University Olomouc, Czech Republic

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Shonali Natu Department of Pathology, University Hospital of North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK

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David Langton Orthopaedic Department, Freeman Hospital, Newcastle upon Tyne, UK

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Monika Huber Pathologisch-bakteriologisches Institut, Otto Wagner Spital, Wien, Austria

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Anastasia Rakow Department of Orthopedics and Orthopedic Surgery, University Medicine Greifswald, Greifswald, Germany

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Janosch Schoon Department of Orthopedics and Orthopedic Surgery, University Medicine Greifswald, Greifswald, Germany

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Enrique Gomez-Barrena Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario La Paz-IdiPAZ, Universidad Autónoma de Madrid, Madrid, Spain

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Veit Krenn MVZ-Zentrum für Histologie, Zytologie und Molekulare Diagnostik-GmbH, Trier, Germany

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complication of joint arthroplasty and not a form of ALTR/ARMD, its classification might change if a higher prevalence is found in MoM and non-MoM hip implants at risk for ALTR/ARMD. In a retrospective study of 104 cases of failed MoM HRA and THA hip

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Anne Lübbeke Division of Orthopaedic Surgery and Traumatology, Geneva University Hospitals and University of Geneva, Switzerland
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK

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James A. Smith Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK

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Daniel Prieto-Alhambra Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK

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Andrew J. Carr Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK

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.g. comprehensive and collaborative pre-market assessment, 24 full-cycle failure analyses, and systematic integration of imaging in early clinical implant surveillance. Studying the causes of why and how implants succeed or fail – in a cross-disciplinary way

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Haroon Majeed Manchester University Foundation NHS Trust, Manchester, UK

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280,671,477 Inappropriate treatment 763 114,743,251 Operator error 413 50,871,568 Failed follow-up arrangements 95 6,460,554 Performed operation not indicated 88 15,368,005 Delay in referring to

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Juan Carlos Monllau Department of Orthopaedic Surgery, Hospital del Mar, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
ICATKnee, Institut Catalá de Traumatologia i Medicina de l’Esport (ICATME), Hospital Universitari Dexeus, UAB, Barcelona, Spain

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Simone Perelli Department of Orthopaedic Surgery, Hospital del Mar, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain
ICATKnee, Institut Catalá de Traumatologia i Medicina de l’Esport (ICATME), Hospital Universitari Dexeus, UAB, Barcelona, Spain

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Giuseppe Gianluca Costa Orthopaedic Surgery Department, Ospedale Umberto I, Enna, Italy

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. Historically, a failed ACL reconstruction was defined by the presence of abnormal anteroposterior or rotatory knee instability ( 6 ). However, a recent meta-analysis reported 34% of patients undergoing ACL reconstruction had a positive Lachman test and 24% of

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Enrique Gómez-Barrena Department of Orthopaedic Surgery and Traumatology, Hospital La Paz-IdiPaz, Universidad Autónoma de Madrid, Madrid, Spain

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Christian Ehrnthaller Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich (MUM), University Hospital, LMU Munich, Germany

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healing without additional intervention ( 8 ). In case a fracture fails to heal after a first (or several) non-union therapeutic procedure(s), the complications and complexity on the patient and the fracture, the sequelae and the already high socioeconomic

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Jeya Palan Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK

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Ciaran Nolan Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK

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Kostas Sarantos Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK

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Richard Westerman Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK

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Richard King Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK

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Pedro Foguet Leeds Teaching Hospitals NHS Trust, Chapel Allerton Hospital, Leeds, UK

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is important to differentiate whether a culture-negative PJI is a true negative (i.e. aseptic loosening) or a false negative result (diagnostic tests have failed to identify an organism but there is a PJI). There are two broad groups of patients who

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E. Carlos Rodríguez-Merchán Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain

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mSv/year is always respected. If after three procedures, RS fails, an AS is indicated. 16 Arthroscopic synovectomy generally achieves similar results to RS; however, as AS is a surgical procedure under general anaesthesia (recommended in

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Andrew Carr Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK

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fail and that large sections of the industry will become non-viable, resulting in bankruptcies and redundancies of large numbers of staff employed in this sector. It is clear that there is a strong industry lobby to reduce or diminish regulation of

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