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Hagen Fritzsche University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Anne Weidlich University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Klaus-Dieter Schaser University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Elisabeth Mehnert University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Doreen Winkler University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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Stefan Rammelt University Center for Orthopaedics, Trauma and Plastic Surgery, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse, Dresden, Germany

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useful ( 6 ). In particular, primary benign bone tumours require a CT scan for assessment of bony destruction patterns, osteolytic lesions and tissue matrix. If performed with contrast media, angiographic multiplanar 2D- and 3D reconstructions allow for a

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Stijn E. W. Geraets Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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P. Koen Bos Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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Johan van der Stok Department of Orthopaedics, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands

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Preoperative embolization of bone tumours was introduced by Feldman et al in 1975. 36 Following this report, the hypothesis that preoperative embolization of metastases reduces intraoperative blood loss was postulated by some authors during the 80s and 90s

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G. Ulrich Exner Orthopaedie Zentrum Zuerich (ozz), Seestrasse 259, CH 8038 Zurich, Switzerland

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Michael O. Kurrer Gemeinschaftspraxis fuer Pathologie, Caecilienstrasse 3, CH 8032 Zurich, Switzerland

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Nadja Mamisch-Saupe Klinik Hirslanden, Department of Musculoskeletal Radiology, Witellikerstrasse 40, 8032 Zurich, Switzerland

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Stephen R. Cannon BMI The Clementine Churchill Hospital, Sudbury Hill, Harrow, Middlesex HA1 3RX, Great Britain

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tuberculosis 11 , 12 which can all mimic a primary neoplasm. Perhaps the most common lesion-mimicking bone tumour or infection is a stress fracture. 13 Similarly, many sarcomata, particularly Ewing’s sarcoma, are well documented to mimic infection

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Julie J. Willeumier Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Yvette M. van der Linden Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Michiel A.J. van de Sande Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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P.D. Sander Dijkstra Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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a primary bone tumour until proven otherwise. Denying this possibility might deprive patients of correct and curative treatments. If the patient has no history of malignancy, a (PET-)CT scan of the chest and abdomen should be performed. In case no

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Zsombor Panti Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Mihai Nica Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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-sparing surgery dominates the modern management of primary malignant bone tumours. For the reconstruction of massive bone defects resulted after the resection of bone sarcoma standard nowadays is the use of modular endoprosthetic systems, performed usually in

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Han Ling Tan Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Tunku Sara Ahmad Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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C Sankara Kumar Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Yohan Khirusman Adnan Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Lai Meng Looi Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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Jayaletchumi Gunasagaran Department of Orthopaedic Surgery (NOCERAL), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

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://doi.org/10.1053/hupa.2001.25903 ) 3 WHO Classification of Tumours Editorial Board . Soft tissue and bone tumours . WHO classification of tumours series , 5th ed. , vol. 3 . Lyon , France : International Agency for Research on Cancer 2020 . Available at

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Daniel Bachman University of Missouri-Kansas City, Kansas City, USA

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Akin Cil University of Missouri-Kansas City, Kansas City, USA

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nonunion (19%), and post-traumatic osteoarthritis (7%). 15 Other less frequent indications are reconstruction following primary or metastatic bone tumour resection 16 and ankylosis. 17 TEA procedures that are performed for inflammatory

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Elisa Pala Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Giulia Trovarelli Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Andrea Angelini Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Maria Chiara Cerchiaro Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Orthopedic Oncology, University of Padova, Padova, Italy

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related to the subject of this article. References 1 WHO Classification of Tumours Editorial B oard . Soft tissue and bone tumours-aneurysmal bone cyst . World Health Organization Classification of Tumours , vol. 6 , 5th ed . Lyon

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Chengxiang Li Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
University of Basel, Basel, Switzerland

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Fatime Krasniqi Department of Oncology, University Hospital Basel, Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland

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Ricardo Donners The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Department of Radiology, University Hospital Basel, Basel, Switzerland

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Christoph Kettelhack The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland
Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland

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Andreas H Krieg Department of Orthopedic, University Children´s Hospital (UKBB), Basel, Switzerland
The Bone and Soft Tissue Tumor Center of the University of Basel (KWUB), Basel, Switzerland

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Weichteilsarkom Studiengruppe (CWS) . Journal of Cancer Research and Clinical Oncology 2020 146 953 – 960 . ( https://doi.org/10.1007/s00432-019-03121-9 ) 20 Board W CoTE. WHO Classification of Tumours: Soft Tissue and Bone Tumours . Lyon , France

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Andrea Angelini Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy

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Ivan Bohacek Department of Orthopaedic Surgery, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, Salata, Zagreb, Croatia

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Mihovil Plecko Department of Orthopaedic Surgery, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, Salata, Zagreb, Croatia

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Carlo Biz Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy

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Giulia Trovarelli Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy

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Mariachiara Cerchiaro Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy

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Giuseppe Di Rubbo Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy

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Pietro Ruggieri Department of Orthopedics and Traumatology and Oncological Orthopedics, University of Padova, Italy

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wide resection of the entire distal fibula in malignant bone tumours . International Orthopaedics 2011 35 87 – 92 . ( https://doi.org/10.1007/s00264-009-0931-x ) 32 Schuurman W & Willems WJ . Lateral ankle reconstruction using a patellar

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