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James R. Berstock Musculoskeletal Research Unit, University of Bristol, UK

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James R. Murray Avon Orthopaedic Centre, Southmead Hospital, Bristol, UK

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Michael R. Whitehouse Musculoskeletal Research Unit, University of Bristol, UK

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Ashley W. Blom Musculoskeletal Research Unit, University of Bristol, UK

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Andrew D. Beswick Musculoskeletal Research Unit, University of Bristol, UK

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Introduction Although several surgical approaches to the knee exist, the medial parapatellar approach has been used in 93% of primary total knee replacements (TKRs) performed in England and Wales between 2004 and 2014. 1 This approach

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Lorenzo Massimo Oldrini Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Alessandro Sangiorgio Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Pietro Feltri Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Francesco Marbach Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland

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Giuseppe Filardo Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland
Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland

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Christian Candrian Service of Orthopaedics and Traumatology, Department of Surgery, EOC, Lugano, Switzerland
Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland

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remains controversial, with two main approaches being widely used: ORIF with open deltopectoral (DP) approach and minimally invasive plate osteosynthesis (MIPO) with deltosplit (DS) approach. The first one is the most common ( 15 , 16 ), being worldwide

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Pietro Feltri Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland

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Camilla Mondini Trissino da Lodi Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland

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Alberto Grassi II Clinica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Stefano Zaffagnini II Clinica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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Christian Candrian Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland
Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland

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Giuseppe Filardo Orthopaedics and Traumatology Clinic, EOC, Lugano, Switzerland
Applied and Translational Research Center, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland

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pain, lower complication rates along with good long-term survivorship and kinematics. 10 , 11 A great effort has been made to introduce and improve the minimally invasive approach for UKA surgery, allowing recovery to be shortened and the

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Rafik Yassa North West Deanery, Manchester, UK

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Mahdi Yacine Khalfaoui North West Deanery, Manchester, UK

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Ihab Hujazi North West Deanery, Manchester, UK

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Hannah Sevenoaks North West Deanery, Manchester, UK

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Paul Dunkow Blackpool Victoria Teaching Hospitals, Blackpool, UK

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a high risk of bleeding due to the multiple soft-tissue layers breached during the surgical approaches and the associated bleeding from displaced fractures. 19 , 20 VKA reversal is therefore crucial before most orthopaedic interventions. An INR

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Irina-Anca Eremia Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania

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Mihnea Popa Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania

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Adela Iancu Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

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Silvia Nica Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Emergency Medicine, Emergency University Hospital, Bucharest, Romania

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Department of Orthopaedics and Traumatology, Emergency University Hospital Bucharest, Romania

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comprehension of RCC’s metastatic mechanisms to bone emphasizes the necessity for a multidisciplinary approach to management, incorporating targeted therapies that tackle the distinct molecular interactions propelling bone degradation ( 36 ). As research

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Jennette Higgs Food to Fit Ltd., PO Box 6057, Greens Norton, Northamptonshire, NN12 8GG, United Kingdom

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Emma Derbyshire Nutritional Insight Ltd., Surrey, KT17 2AA, United Kingdom

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Kathryn Styles Food to Fit Ltd., PO Box 6057, Greens Norton, Northamptonshire, NN12 8GG, United Kingdom

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. Previously, there has been a general tendency to focus on individual nutrients, or supplements, rather than a ‘whole diet’ approach. It is now well accepted that a healthy diet can help to prevent non-communicable diseases, such as osteoporosis, with

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May Fong Mak Center for Surgery of the Foot & Ankle, Hirslanden Clinique La Colline, Switzerland; Department of Orthopaedics, Waikato Hospital, New Zealand

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Richard Stern Center for Surgery of the Foot & Ankle, Hirslanden Clinique La Colline, Switzerland

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Mathieu Assal Center for Surgery of the Foot & Ankle, Hirslanden Clinique La Colline, Switzerland

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Introduction The operative goal in the treatment of ankle fractures is well established: to restore anatomy and stability for early movement and full functional recovery, and prevent post-traumatic arthritis. However, the surgical approach

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Kavin Sundaram Cleveland Clinic Foundation, Department of Orthopedics Cleveland, Ohio, USA

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Ahmed Siddiqi Cleveland Clinic Foundation, Department of Orthopedics Cleveland, Ohio, USA

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Atul F. Kamath Cleveland Clinic Foundation, Department of Orthopedics Cleveland, Ohio, USA

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Carlos A. Higuera-Rueda Cleveland Clinic Florida, Department of Orthopedics Weston, Florida, USA

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primary hip arthroplasty. 1 – 3 There has been renewed interest in variants of this technique including the trochanteric slide osteotomy (TSO), extended trochanter osteotomy (ETO), and the transfemoral approach for both septic and aseptic revision

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Maria Anna Smolle Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Sandra Bösmüller AUVA Trauma Centre Vienna Meidling, Vienna, Austria

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Paul Puchwein Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Martin Ornig Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Andreas Leithner Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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Franz-Josef Seibert Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria

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, with specific constellations as polytrauma, vascular injury, instability, or open fracture demanding a surgical approach ( 5 , 6 ). The frequency of surgical therapy has increased over the years ( 7 ), including plate osteosynthesis via a conventional

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G. Ulrich Exner Orthopaedie Zentrum Zuerich (ozz), Seestrasse 259, CH 8038 Zurich, Switzerland

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Michael O. Kurrer Gemeinschaftspraxis fuer Pathologie, Caecilienstrasse 3, CH 8032 Zurich, Switzerland

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Nadja Mamisch-Saupe Klinik Hirslanden, Department of Musculoskeletal Radiology, Witellikerstrasse 40, 8032 Zurich, Switzerland

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Stephen R. Cannon BMI The Clementine Churchill Hospital, Sudbury Hill, Harrow, Middlesex HA1 3RX, Great Britain

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literature review by Traina et al 1 outlines the general approach to performing biopsies of bone and soft tissue, respectively. As there is no single standard approach for biopsy for very different conditions, personal opinions and judgement influence

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