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Akintunde George Centre for Integrated Bioprocessing Research, Department of Chemical Engineering, University of Bath, Bath, UK

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Marianne Ellis Centre for Integrated Bioprocessing Research, Department of Chemical Engineering, University of Bath, Bath, UK

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Harinderjit Singh Gill Department of Mechanical Engineering, University of Bath, Bath, UK

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the pathophysiology of avascular necrosis caused by sickle cell disease. It seeks to establish certain research methodology frameworks in exploring how osseointegration could be improved in sickle cell disease patients with prosthetic implants

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Julie J. Willeumier Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Yvette M. van der Linden Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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Michiel A.J. van de Sande Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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P.D. Sander Dijkstra Department of Orthopaedics, Leiden University Medical Centre, The Netherlands

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of adjuvant cement. The downsides of using a plate include the large incision needed, a longer surgical procedure and the lack of prophylactic fixation of the entire bone. Prosthetic reconstructions (endoprostheses, segmental prostheses, hemi- and

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Catalin Cirstoiu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Cretu Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Bogdan Serban Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Zsombor Panti Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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Mihai Nica Carol Davila University of Medicine and Pharmacy, Orthopedics and Traumatology Department, Bucharest, Romania
University Emergency Hospital Bucharest, Romania

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complications such as structural failure, peri-prosthetic fracture, aseptic loosening or infection. The APC usually consists of a revision type implant combined with a bone allograft which is the element that presumably improves stability and soft

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Georgios Tsikandylakis Department of Orthopaedics, Sahlgrenska University Hospital, Gothenburg, Sweden
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden
Swedish Hip Arthroplasty Register, Gothenburg, Sweden

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Maziar Mohaddes Department of Orthopaedics, Sahlgrenska University Hospital, Gothenburg, Sweden
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden
Swedish Hip Arthroplasty Register, Gothenburg, Sweden

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Peter Cnudde Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden
Swedish Hip Arthroplasty Register, Gothenburg, Sweden
Department of Orthopaedics, Prince Philip Hospital, HDUHB, Wales

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Antti Eskelinen Coxa Hospital for Joint Replacement, Tampere, Finland
Finnish Arthroplasty Register, Helsinki, Finland

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Johan Kärrholm Department of Orthopaedics, Sahlgrenska University Hospital, Gothenburg, Sweden
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden
Swedish Hip Arthroplasty Register, Gothenburg, Sweden

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Ola Rolfson Department of Orthopaedics, Sahlgrenska University Hospital, Gothenburg, Sweden
Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden
Swedish Hip Arthroplasty Register, Gothenburg, Sweden

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wear that might lead to implant loosening, as well as taper corrosion (trunnionosis) and a higher risk of groin pain. In this paper, we have summarized the evidence behind each of these arguments. Head size and range of movement of the prosthetic

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Demien Broekhuis Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Rutger Tordoir Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Zoe Vallinga Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Jan Schoones Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Bart Pijls Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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Rob Nelissen Department of Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands

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-related complications  Prosthetic joint infection 31 1069 4.9% 3.3–6.5%  Dislocation 30 1006 6.6% 4.7–8.6%  Nerve lesion 21 743 2.0% 0.9–3.1%  Screw failure 23 714 2.1% 1.0–3.1%  Aseptic loosening

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Carsten Perka Center for Musculoskeletal Surgery, Charité Medical University Center, Berlin, Germany

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Maziar Mohaddes Hässleholms Hospital, Region Skåne, Hässleholm, Sweden
Orthopedics, Faculty of Medicine, Department of Clinical Sciences, Lund University, Malmö, Sweden

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Luigi Zagra Hip Department, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy

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Axel Ekkernkamp BG Klinikum Unfallkrankenhaus Berlin gGmbH, Berlin, Germany
BG Kliniken – Klinikverbund der gesetzlichen Unfallversicherung gGmbH, Berlin, Germany

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Niklas Keller Harding Center for Risk Literacy, University of Potsdam, Faculty of Health Sciences, Potsdam, Germany

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Dirk Stengel BG Kliniken – Klinikverbund der gesetzlichen Unfallversicherung gGmbH, Berlin, Germany

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–zirconia components, we made no restrictions to (i) prosthetic metal hardware produced by any manufacturer, (ii) cemented or uncemented fixation, (iii) surgical access routes, (iv) additional procedures such as accelerated or fast-track rehabilitation, navigation, etc

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Gautier Beckers Department of Surgery, Hospital Maisonneuve-Rosemont, Montreal University, Montreal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA

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Marc-Olivier Kiss Department of Surgery, Hospital Maisonneuve-Rosemont, Montreal University, Montreal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA
Clinique Orthopédique Duval, Laval, Quebec, Canada

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Vincent Massé Department of Surgery, Hospital Maisonneuve-Rosemont, Montreal University, Montreal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA
Clinique Orthopédique Duval, Laval, Quebec, Canada

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Michele Malavolta Personalized Arthroplasty Society, Atlanta, Georgia, USA
Department of Knee Surgery, Casa di Cura Solatrix, Rovereto, TN, Italy

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Pascal-André Vendittoli Department of Surgery, Hospital Maisonneuve-Rosemont, Montreal University, Montreal, Quebec, Canada
Personalized Arthroplasty Society, Atlanta, Georgia, USA
Clinique Orthopédique Duval, Laval, Quebec, Canada

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constitutional anatomies might predispose the patient to arthritis ( 18 ) and prosthetic complications if recreated during surgery ( 19 ). For these reasons, limb and joint alignment boundaries are still debated ( 19 , 20 , 21 ). More outlying anatomies may be

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Xinhuan Lei Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Jie Xiang Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hailan Yang Department of Ultrasound, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hongya Bao Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Zhong Zhu Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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Hua Luo Department of Orthopedic, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China

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, prosthetic infection is with an incidence rate of 0.69–2.2% ( 13 , 14 ). Once infection occurs, it requires surgery and long-term use of antibiotics to be treated, and treatment failure is common. Given the difficulty of treating infections, preventing

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Karl Stoffel Department of Orthopaedics and Traumatology, University Hospital Basel, Basel, Switzerland

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Tamara Horn Clinic of Orthopaedic Surgery, Kantonsspital Baselland, Liestal, Switzerland

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Luigi Zagra Hip Department, IRCCS Galeazzi Orthopaedic Institute, Milano, Italy

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Michael Mueller Orthopaedic Department, Charité – Universitätsmedizin Berlin, Berlin, Germany

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Carsten Perka Orthopaedic Department, Charité – Universitätsmedizin Berlin, Berlin, Germany

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Henrik Eckardt Department of Orthopaedics and Traumatology, University Hospital Basel, Basel, Switzerland

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. Functional outcome of femoral peri prosthetic fracture and revision hip arthroplasty: a matched-pair study from the New Zealand Registry . Acta Orthop 2008 ; 79 : 483 – 488 . 14. Bhattacharyya T Chang D Meigs JB Estok

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Lars Adolfsson Department of Orthopaedics, University Hospital of Linköping, Sweden

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alternative to prosthetic replacement. Manipulation under anaesthesia There are few reports describing results after this procedure and we have seen referred cases with iatrogenic fractures caused by aggressive manipulation under anaesthesia without

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