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, physical examination and identification of risk factors As in all medical decision-making, clinical suspicion of a PJI is conceived during anamnesis and physical examination. Signs of infection include erythema, oedema, warmth, tenderness and/or fever
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of interest and may be a risk factor (e.g. smoking status) or treatment type (e.g. surgical versus non-surgical treatment) or other. The conceptual framework of a particular study is determined by its specific exposure–outcome relation and also
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profile is still undergoing investigation given its high associated risk with thromboembolic events including stroke and transient ischaemic attacks ( 52 , 54 ). PCC is a plasma-derived concentrate of vitamin K-dependent clotting factors ( 52 ). To date
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3906 patients, Richards et al reported a six times greater risk of infection when performing RSA, when compared to an unconstrained TSA. 34 They found younger age and male gender to be risk factors for an infection, and this is consistent with
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– significant perioperative blood loss, estimated to range from 1450 mL to 1790 mL without specific interventions ( 3 ). Understanding the determinants of preexisting thromboembolic risk is pivotal for individuals undergoing TJA. Patients with a history of
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and mortality. 5 Recently it was shown that delay to surgery of more than 24 hrs is a risk factor for wound infection. 6 Therefore, in England, National Health Service (NHS) Trusts are incentivized by a ‘best practice’ tariff (extra financial
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method. Unfortunately, most of the studies we included in this analysis failed to report on co-morbidities and other influencing factors ( 11 , 14 , 15 , 16 ). There are certain intrinsic risk factors that make one patient more prone to non-unions than
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scientific department with medical expertise in each major clinical field. High-risk implantable medical devices are essential for clinical care. Scrutiny of clinical evidence before their market access is also essential. Uncertainty about the standards
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significant maltracking factors and concomitant osteochondral fractures are ruled out. 23 In mixed cohorts which were not divided into subgroups with different risk patterns, the 3–5-year recurrence rate varied between 35% and 70%, but the long
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, when the graft size was 7.5 mm to 8 mm, 9 of 139 patients (6.5%) required a revision ACL surgery, respectively, compared with 8 of 59 patients (13.6%) with grafts of ⩽ 7 mm in diameter. They also evaluated age as a potential risk factor for revision
